Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Shujun Luo"'
Autor:
Michael J. Keogh, Wei Wei, Juvid Aryaman, Lauren Walker, Jelle van den Ameele, Jon Coxhead, Ian Wilson, Matthew Bashton, Jon Beck, John West, Richard Chen, Christian Haudenschild, Gabor Bartha, Shujun Luo, Chris M. Morris, Nick S. Jones, Johannes Attems, Patrick F. Chinnery
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Similar to cancers, somatic mutations might lead to neurodegenerative diseases. Here, the authors perform ultra-deep sequencing of 102 genes in 173 adult human brains, detect somatic mutations in 54 brains, and develop a mathematical model to estimat
Externí odkaz:
https://doaj.org/article/4340dcba8f0b45e0b3cd339e05e6fd88
Autor:
Gordon M Cann, Zulfiqar G Gulzar, Samantha Cooper, Robin Li, Shujun Luo, Mai Tat, Sarah Stuart, Gary Schroth, Sandhya Srinivas, Mostafa Ronaghi, James D Brooks, Amirali H Talasaz
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49144 (2012)
Circulating tumor cells (CTC) mediate metastatic spread of many solid tumors and enumeration of CTCs is currently used as a prognostic indicator of survival in metastatic prostate cancer patients. Some evidence suggests that it is possible to derive
Externí odkaz:
https://doaj.org/article/3a9e96b802f243c6b9ee79b29e025b93
Autor:
Xinxia Peng, Lisa Gralinski, Martin T. Ferris, Matthew B. Frieman, Matthew J. Thomas, Sean Proll, Marcus J. Korth, Jennifer R. Tisoncik, Mark Heise, Shujun Luo, Gary P. Schroth, Terrence M. Tumpey, Chengjun Li, Yoshihiro Kawaoka, Ralph S. Baric, Michael G. Katze
Publikováno v:
mBio, Vol 2, Iss 6 (2011)
ABSTRACT We previously reported widespread differential expression of long non-protein-coding RNAs (ncRNAs) in response to virus infection. Here, we expanded the study through small RNA transcriptome sequencing analysis of the host response to both s
Externí odkaz:
https://doaj.org/article/99ba8206fafc4139834b97a8048ef817
Autor:
Susan E Lott, Jacqueline E Villalta, Gary P Schroth, Shujun Luo, Leath A Tonkin, Michael B Eisen
Publikováno v:
PLoS Biology, Vol 9, Iss 2, p e1000590 (2011)
When Drosophila melanogaster embryos initiate zygotic transcription around mitotic cycle 10, the dose-sensitive expression of specialized genes on the X chromosome triggers a sex-determination cascade that, among other things, compensates for differe
Externí odkaz:
https://doaj.org/article/ad0d851dd23c428091d5041bc13a2c8e
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23501 (2011)
We describe a new algorithm, meraculous, for whole genome assembly of deep paired-end short reads, and apply it to the assembly of a dataset of paired 75-bp Illumina reads derived from the 15.4 megabase genome of the haploid yeast Pichia stipitis. Mo
Externí odkaz:
https://doaj.org/article/685d67c455ea469f9022be634989dccd
Autor:
Zhifu Sun, Yan W Asmann, Krishna R Kalari, Brian Bot, Jeanette E Eckel-Passow, Tiffany R Baker, Jennifer M Carr, Irina Khrebtukova, Shujun Luo, Lu Zhang, Gary P Schroth, Edith A Perez, E Aubrey Thompson
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17490 (2011)
We used deep sequencing technology to profile the transcriptome, gene copy number, and CpG island methylation status simultaneously in eight commonly used breast cell lines to develop a model for how these genomic features are integrated in estrogen
Externí odkaz:
https://doaj.org/article/136011bdbb994284ba2dd999ab454605
Autor:
Hideo Matsumura, Kentaro Yoshida, Shujun Luo, Eiji Kimura, Takahiro Fujibe, Zayed Albertyn, Roberto A Barrero, Detlev H Krüger, Günter Kahl, Gary P Schroth, Ryohei Terauchi
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12010 (2010)
We established a protocol of the SuperSAGE technology combined with next-generation sequencing, coined "High-Throughput (HT-) SuperSAGE". SuperSAGE is a method of digital gene expression profiling that allows isolation of 26-bp tag fragments from exp
Externí odkaz:
https://doaj.org/article/8b9d9dcfeb534fb789af35cbb6b549d1
Autor:
Joann Mudge, Neil A Miller, Irina Khrebtukova, Ingrid E Lindquist, Gregory D May, Jim J Huntley, Shujun Luo, Lu Zhang, Jennifer C van Velkinburgh, Andrew D Farmer, Sharon Lewis, William D Beavis, Faye D Schilkey, Selene M Virk, C Forrest Black, M Kathy Myers, Lar C Mader, Ray J Langley, John P Utsey, Ryan W Kim, Rosalinda C Roberts, Sat Kirpal Khalsa, Meredith Garcia, Victoria Ambriz-Griffith, Richard Harlan, Wendy Czika, Stanton Martin, Russell D Wolfinger, Nora I Perrone-Bizzozero, Gary P Schroth, Stephen F Kingsmore
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3625 (2008)
Schizophrenia (SCZ) is a common, disabling mental illness with high heritability but complex, poorly understood genetic etiology. As the first phase of a genomic convergence analysis of SCZ, we generated 16.7 billion nucleotides of short read, shotgu
Externí odkaz:
https://doaj.org/article/4360517c74a24c5291d58ba756a00d2d
Objective: To analyze the relationship between lifestyle habits and scoliosis severity in children with idiopathic early-onset scoliosis (IEOS). Method: A total of 208 children with IEOS were enrolled. Lifestyle habits and Cobb’s angles were collec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d2234ba550578d6875ec21348a6fd03
https://doi.org/10.21203/rs.3.rs-2534229/v1
https://doi.org/10.21203/rs.3.rs-2534229/v1
Autor:
Andrew Davis, Jingqin Luo, Tiantian Zheng, Lu Tan, Amy Wang, Rama Suresh, Foluso Ademuyiwa, Caron Rigden, Timothy Rearden, Katherine Clifton, Katherine Weilbaecher, Ashley Frith, Pavan K Tandra, Tracy Summa, Brittney Haas, Shana Thomas, Leonel Hernandez-Aya, Lindsay Peterson, Shujun Luo, Bonnie L King, Shidong Jia, Jianjun Yu, Pan Du, Jairam Krishnamurthy, Cynthia X Ma, C Dai
Publikováno v:
Cancer Research. 82:P2-07
Background: CDK4/6i combined with ET improves survival for pts with HR+, HER2- MBC. However, biomarkers to predict efficacy and resistance are needed. We hypothesized that a comprehensive next-generation sequencing (NGS)-based liquid biopsy assessmen