Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Shujuan Lai"'
Autor:
Shuyuan Yang, Xiaoyu Lu, Michelle Land, Zhuohe Liu, Alex Mcdonald, Yueyang Gou, Yunmiao Wang, Elsayed Zaabout, Xiaoyu Dong, Shujuan Lai, Dieter Jaeger, Jacob Reimer, François St-Pierre
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S264-S265 (2023)
Externí odkaz:
https://doaj.org/article/11e80b2fc5074767a58be6b5de10ce94
Autor:
Yaqiang Hong, Dake Zhang, Xiangtian Zhou, Aili Chen, Amir Abliz, Jian Bai, Liang Wang, Qingtao Hu, Kenan Gong, Xiaonan Guan, Mengfei Liu, Xinchang Zheng, Shujuan Lai, Hongzhu Qu, Fuxin Zhao, Shuang Hao, Zhen Wu, Hong Cai, Shaoyan Hu, Yue Ma, Junting Zhang, Yang Ke, Qian-Fei Wang, Wei Chen, Changqing Zeng
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 1, Pp 177-191 (2022)
Postzygotic mutations are acquired in normal tissues throughout an individual’s lifetime and hold clues for identifying mutagenic factors. Here, we investigated postzygotic mutation spectra of healthy individuals using optimized ultra-deep exome se
Externí odkaz:
https://doaj.org/article/40f7d499a249494bb108fc3b3d79f158
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Transient plasmid transfection produces a wide distribution of copy numbers and expression heterogeneity. Here the authors present synthetic circuits called Equalizers that buffer copy number variation at the single-cell level and minimize cell-to-ce
Externí odkaz:
https://doaj.org/article/3624485f7c5c49edb625fe43b2b5f8d9
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Detection ofde novo, low frequency mutations is important for characterising heterogeneous cell populations, such as those found in cancer cell populations. Here the authors present o2n-seq, an ultrasensitive method with highly efficient data usage f
Externí odkaz:
https://doaj.org/article/6fd788ebdd2d4aa9a1ab98de73353467
Autor:
Qiyan Wang, Jian Bai, Amir Abliz, Ying Liu, Kenan Gong, Jingjing Li, Wenjie Shi, Yaqi Pan, Fangfang Liu, Shujuan Lai, Haijun Yang, Changdong Lu, Lixin Zhang, Wei Chen, Ruiping Xu, Hong Cai, Yang Ke, Changqing Zeng
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 13, Iss 4, Pp 258-270 (2015)
Esophageal squamous cell carcinoma (ESCC) has a high mortality rate. To determine the molecular basis of ESCC development, this study sought to identify characteristic genome-wide alterations in ESCC, including exonic mutations and structural alterat
Externí odkaz:
https://doaj.org/article/ea2e8c3c7ed24ac2bed65a7bb458ead4
Autor:
Zhuohe Liu, Xiaoyu Lu, Vincent Villette, Yueyang Gou, Kevin L. Colbert, Shujuan Lai, Sihui Guan, Michelle A. Land, Jihwan Lee, Tensae Assefa, Daniel R. Zollinger, Maria M. Korympidou, Anna L. Vlasits, Michelle M. Pang, Sharon Su, Changjia Cai, Emmanouil Froudarakis, Na Zhou, Saumil S. Patel, Cameron L. Smith, Annick Ayon, Pierre Bizouard, Jonathan Bradley, Katrin Franke, Thomas R. Clandinin, Andrea Giovannucci, Andreas S. Tolias, Jacob Reimer, Stéphane Dieudonné, François St-Pierre
Publikováno v:
Cell
Cell, 2022, 185 (18), pp.3408-3425.e29. ⟨10.1016/j.cell.2022.07.013⟩
Cell, 2022, 185 (18), pp.3408-3425.e29. ⟨10.1016/j.cell.2022.07.013⟩
International audience; Genetically encoded voltage indicators are emerging tools for monitoring voltage dynamics with cell-type specificity. However, current indicators enable a narrow range of applications due to poor performance under two-photon m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628e7939a22097f1a78b007bb0e76580
https://hal.science/hal-03795400/document
https://hal.science/hal-03795400/document
Autor:
Deng Wu, Yunao Liu, Wei Chen, Jianming Shao, Pubu Zhuoma, Dexiong Zhao, Yang Yu, Tianzi Liu, Ruoxuan Yu, Yongna Gan, Baima Yuzheng, Yongshu Huang, Haikun Zhang, Xiaoman Bi, Chengcheng Tao, Shujuan Lai, Qiaoxia Luo, Dake Zhang, Hongmei Wang, Pingcuo Zhaxi, Jianqing Zhang, Jie Qiao, Changqing Zeng
Publikováno v:
Molecular Biology and Evolution. 39
As the best adapted high altitude population, Tibetans feature a relatively high offspring survival rate. Genome-wide studies have identified hundreds of candidate SNPs related to high altitude adaptation of Tibetans, although most of them have unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c05525b40c9ec87c2d1625b80bf705f
https://doi.org/10.1093/molbev/msac120
https://doi.org/10.1093/molbev/msac120
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Precise control of gene expression is critical for biological research and biotechnology. However, transient plasmid transfections in mammalian cells produce a wide distribution of copy numbers per cell, and consequently, high expression heterogeneit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb24283808b9126022652810eed840e
https://doi.org/10.1038/s41467-021-23889-0
https://doi.org/10.1038/s41467-021-23889-0
Autor:
Zhuohe Liu, Sihui Guan, Shujuan Lai, Jihwan Lee, Peter H. Suzuki, Xiaoyu Lu, John F. Ahrens, François St-Pierre
Publikováno v:
Science Advances
Versatile high-throughput method can isolate single cells based on spatiotemporal phenotypes.
Unraveling the genetic and epigenetic determinants of phenotypes is critical for understanding and re-engineering biology and would benefit from improv
Unraveling the genetic and epigenetic determinants of phenotypes is critical for understanding and re-engineering biology and would benefit from improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203996af5c6cf000b22095d9fbbd84d7
https://doi.org/10.1126/sciadv.abb7438
https://doi.org/10.1126/sciadv.abb7438
Autor:
Liang Wang, Zhen Wu, Jian Bai, Hong Cai, Shaoyan Hu, Mengfei Liu, Qingtao Hu, Fuxin Zhao, Xinchang Zheng, Shuang Hao, Yue Ma, Hongzhu Qu, Shujuan Lai, Xiangtian Zhou, Amir Abliz, Aili Chen, Xiaonan Guan, Changqing Zeng, Junting Zhang, Dake Zhang, Yang Ke, Wei Chen, Kenan Gong, Qianfei Wang, Yaqiang Hong
Postzygotic mutations are acquired in all of the normal tissues throughout an individual’s lifetime and hold clues for identifying mutagenesis causing factors. The process and underlying mechanism of postzygotic mutations in normal tissues is still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14e0a5f0e7ff1d7db3c48a75d3d9dca