Zobrazeno 1 - 10
of 362
pro vyhledávání: '"Shujiro OKUDA"'
Autor:
Hiroshi Ichikawa, Kenji Usui, Masaki Aizawa, Yoshifumi Shimada, Yusuke Muneoka, Yosuke Kano, Mika Sugai, Kazuki Moro, Yuki Hirose, Kohei Miura, Jun Sakata, Hiroshi Yabusaki, Satoru Nakagawa, Takashi Kawasaki, Hajime Umezu, Shujiro Okuda, Toshifumi Wakai
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Evaluation of human epidermal growth factor receptor 2 (HER2) overexpression caused by erb-b2 receptor tyrosine kinase 2 (ERBB2) amplification (AMP) by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) is es
Externí odkaz:
https://doaj.org/article/58024c73781244c2a550d82427280eba
Autor:
Yu Takeuchi, Shinya Sato, Chikako Nagasato, Taizo Motomura, Shujiro Okuda, Masahiro Kasahara, Fumio Takahashi, Shinya Yoshikawa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Spermatogenesis is one of the most dramatic changes in cell differentiation. Remarkable chromatin condensation of the nucleus is observed in animal, plant, and algal sperm. Sperm nuclear basic proteins (SNBPs), such as protamine and sperm-sp
Externí odkaz:
https://doaj.org/article/315b551a7ad544ef928a91dff5a8d988
Autor:
Amina K. Shaban, Gebremichal Gebretsadik, Mariko Hakamata, Hayato Takihara, Erina Inouchi, Akihito Nishiyama, Yuriko Ozeki, Yoshitaka Tateishi, Yukiko Nishiuchi, Takehiro Yamaguchi, Naoya Ohara, Shujiro Okuda, Sohkichi Matsumoto
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Survival of the live attenuated Bacillus Calmette-Guérin (BCG) vaccine amidst harsh host environments is key for BCG effectiveness as it allows continuous immune response induction and protection against tuberculosis. Mycobacterial DNA bind
Externí odkaz:
https://doaj.org/article/61dd04c5205849a3bb027beab3339312
Autor:
Hiroyuki Abe, Kenya Kamimura, Shujiro Okuda, Yu Watanabe, Jun Inoue, Yutaka Aoyagi, Toshifumi Wakai, Ryo Kominami, Shuji Terai
Publikováno v:
Cancer Medicine, Vol 12, Iss 14, Pp 15650-15663 (2023)
Abstract Introduction B‐cell lymphoma/leukemia 11B (BCL11B) is a subunit of SWI/SNF chromatin remodeling complexes and functions in cell cycle regulation and apoptosis upon DNA replication stress and damages via transcription. Many malignancies wer
Externí odkaz:
https://doaj.org/article/b28136d80b664370b096168307a180cc
Autor:
Nobuaki Miura, Shujiro Okuda
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1140-1150 (2023)
Metaproteomics is a relatively young field that has only been studied for approximately 15 years. Nevertheless, it has the potential to play a key role in disease research by elucidating the mechanisms of communication between the human host and the
Externí odkaz:
https://doaj.org/article/61aa80d0514c48d8aa55c2956a541cc0
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The examination of urinary sediment crystals, the sedimentary components of urine, is useful in screening tests, and is always performed in medical examinations. The examination of urinary sediment crystals is typically done by classifying t
Externí odkaz:
https://doaj.org/article/dde06cf323ea4ca98662a87b8e74d907
Autor:
Yosuke Tajima, Shujiro Okuda, Tsunekazu Hanai, Junichiro Hiro, Koji Masumori, Yoshikazu Koide, Tadahiro Kamiya, Yeongcheol Cheong, Gaku Inaguma, Yoshifumi Shimada, Toshifumi Wakai, Hayato Takihara, Shingo Akimoto, Hiroshi Matsuoka, Ichiro Uyama, Koichi Suda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The outer mucus layer of the colorectal epithelium is easily removable and colonized by commensal microbiota, while the inner mucus layer is firmly attached to the epithelium and devoid of bacteria. Although the specific bacteria penetrating
Externí odkaz:
https://doaj.org/article/216da80387c249c08ba45d816db172f1
Autor:
Yohko Yoshida, Ippei Shimizu, Atsuhiro Shimada, Keita Nakahara, Sachiko Yanagisawa, Minoru Kubo, Shinji Fukuda, Chiharu Ishii, Hiromitsu Yamamoto, Takamasa Ishikawa, Kuniyuki Kano, Junken Aoki, Goro Katsuumi, Masayoshi Suda, Kazuyuki Ozaki, Yutaka Yoshida, Shujiro Okuda, Shigeo Ohta, Shiki Okamoto, Yasuhiko Minokoshi, Kanako Oda, Toshikuni Sasaoka, Manabu Abe, Kenji Sakimura, Yoshiaki Kubota, Norihiko Yoshimura, Shingo Kajimura, Maria Zuriaga, Kenneth Walsh, Tomoyoshi Soga, Tohru Minamino
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Low body temperature predicts a poor outcome in patients with heart failure, but the underlying pathological mechanisms and implications are largely unknown. Brown adipose tissue (BAT) was initially characterised as a thermogenic organ, and
Externí odkaz:
https://doaj.org/article/47e7cf28377a4d3a94aefb37d6721e18
Autor:
Hayato Takihara, Shujiro Okuda
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Interactions between humans and the gut microbiome occur by supplying nutrients to gut epithelial cells via short-chain fatty acids obtained from dietary carbohydrates or mucins and activating immunity via mucins’ degradation. The degradation of ca
Externí odkaz:
https://doaj.org/article/07b0f62bae1047eebf0c2aa839973684
Autor:
Shujiro Okuda, Yuki Hirose, Hayato Takihara, Akiko Okuda, Yiwei Ling, Yosuke Tajima, Yoshifumi Shimada, Hiroshi Ichikawa, Kazuyasu Takizawa, Jun Sakata, Toshifumi Wakai
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract With the discovery of bacterial symbiosis in the tissues of various cancers, the study of the tumor microbiome is attracting a great deal of attention. Anatomically, since the gastrointestinal tract, liver, and pancreas form a continuous duc
Externí odkaz:
https://doaj.org/article/ffd98563183a4169b27c8e017be1efaa