Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Shuji Yonei"'
Autor:
Masaki Hori, Shin-Ichiro Yonekura, Takehiko Nohmi, Petr Gruz, Hiroshi Sugiyama, Shuji Yonei, Qiu-Mei Zhang-Akiyama
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
Escherichia coli DNA polymerase IV (Pol IV) is involved in bypass replication of damaged bases in DNA. Reactive oxygen species (ROS) are generated continuously during normal metabolism and as a result of exogenous stress such as ionizing radiation. R
Externí odkaz:
https://doaj.org/article/0590cdde7c52476ba2420cf1461c8332
Publikováno v:
Genes & Genetic Systems. 88:175-188
E. coli YdbK is predicted to be a pyruvate:flavodoxin oxidoreductase (PFOR). However, enzymatic activity and the regulation of gene expression of it are not well understood. In this study, we found that E. coli cells overexpressing the ydbK gene had
Autor:
Yoshiaki Tabuchi, Shiga Hasuike, Ichiro Takasaki, Takaharu Nomura, Kazunari Hashiguchi, Takashi Kondo, Qing-Li Zhao, Akira Tachibana, Zheng Li Wei, Ayaka Hosoki, Shuji Yonei, Shin Ichiro Yonekura, Li Li Wang, Qiu-Mei Zhang-Akiyama
Publikováno v:
Journal of Radiation Research. 53:58-71
Reactive oxygen species (ROS) act as a mediator of ionizing radiation-induced cellular damage. Previous studies have indicated that MnSOD (SOD2) plays a critical role in protection against ionizing radiation in mammalian cells. In this study, we cons
Autor:
Shuji Yonei, Petr Grúz, Takehiko Nohmi, Shin Ichiro Yonekura, Masaki Hori, Hiroshi Sugiyama, Qiu-Mei Zhang-Akiyama
Publikováno v:
Journal of Nucleic Acids
Journal of Nucleic Acids, Vol 2010 (2010)
Journal of Nucleic Acids, Vol 2010 (2010)
Escherichia coliDNA polymerase IV (Pol IV) is involved in bypass replication of damaged bases in DNA. Reactive oxygen species (ROS) are generated continuously during normal metabolism and as a result of exogenous stress such as ionizing radiation. RO
Autor:
Shin Ichiro Yonekura, Shuji Yonei, Qiu-Mei Zhang-Akiyama, Masahiro Kikuchi, Kazuo Yamamoto, Hiroshi Sugiyama, Hironobu Morinaga
Publikováno v:
Nucleic Acids Research
The 5-formyluracil (5-foU), a major mutagenic oxidative damage of thymine, is removed from DNA by Nth, Nei and MutM in Escherichia coli. However, DNA polymerases can also replicate past the 5-foU by incorporating C and G opposite the lesion, although
Autor:
Akira Yasui, Kumiko Kobayashi, Shuji Yonei, Yoshitsugu Oohata, Shigenori Iwai, Masashi Takao, Kengo Kitadokoro, Qiu-Mei Zhang
Publikováno v:
Genes to Cells. 14:261-270
Oxidative base damage leads to alteration of genomic information and is implicated as a cause of aging and carcinogenesis. To combat oxidative damage to DNA, cells contain several DNA glycosylases including OGG1, NTH1 and the Nei-like proteins, NEIL1
Autor:
Shuji Yonei, Hironobu Morinaga, Kazuo Yamamoto, Shin Ichiro Yonekura, Nobuya Nakamura, Qiu-Mei Zhang, Naoaki Ishii, Masahiro Kikuchi
Publikováno v:
Mutagenesis. 23:407-413
Uracil arises in DNA from spontaneous deamination of cytosine and through incorporation of dUMP by DNA polymerase during DNA replication. Excision of uracil by the action of uracil-DNA glycosylase (Ung) initiates the base excision repair pathway to c
Autor:
Shin Ichiro Yonekura, Nobuya Nakamura, Kazuo Yamamoto, Hiroshi Sugiyama, Shuji Yonei, Takashi Doi, Qiu-Mei Zhang
Publikováno v:
Journal of Radiation Research. 48:417-424
Bacteria and eukaryotes possess redundant enzymes that recognize and remove oxidatively damaged bases from DNA through base excision repair. DNA glycosylases remove damaged bases to initiate the base excision repair. The exocyclic methyl group of thy
Publikováno v:
International Journal of Radiation Biology. 82:241-250
It is of interest to perform a systematic comparative analysis of the conserved domains in DNA glycosylases and the evolution of DNA base excision repair systems. Furthermore, it is important to characterize the roles and regulation of base excision
Autor:
Akira Yasui, Masashi Takao, Qiu-Mei Zhang, Shuji Yonei, Shin Ichiro Yonekura, Hiroshi Sugiyama
Publikováno v:
DNA Repair. 4:71-79
Bacteria and eukaryotes possess redundant activities that recognize and remove oxidatively damaged bases from DNA through base excision repair. DNA glycosylases excise damaged bases to initiate the base excision repair pathway. hOgg1 and hNTH1, homol