Zobrazeno 1 - 10
of 760
pro vyhledávání: '"Shuji Terai"'
Autor:
Kyutaro Koyama, Akira Sakamaki, Shinichi Morita, Itsuo Nagayama, Marina Kudo, Yuto Tanaka, Naruhiro Kimura, Yoshihisa Arao, Hiroyuki Abe, Kenya Kamimura, Shuji Terai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The onset and progression mechanisms of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) are being studied. We developed and analyzed a new mouse model of obesity by
Externí odkaz:
https://doaj.org/article/0bde0df3e10b4ad49ffb6c6165fcbe67
Autor:
Masaru Kumagai, Atsunori Tsuchiya, Yuan Yang, Nobutaka Takeda, Kazuki Natsui, Yui Natusi, Kei Tomiyoshi, Fusako Yamazaki, Yohei Koseki, Hiroki Shinchi, Naoko Imawaka, Ryo Ukekawa, Takahiro Nishibu, Hiroyuki Abe, Takako Sasaki, Koji Ueda, Shuji Terai
Publikováno v:
FEBS Open Bio, Vol 14, Iss 8, Pp 1264-1276 (2024)
Chronic liver injury leads to decreased liver function and increased fibrosis. Fibrosis is not only associated with the development of portal hypertension and carcinogenesis, but with the occurrence of events and a poor prognosis, highlighting the im
Externí odkaz:
https://doaj.org/article/9d21237a27c448d1b35fe7dc75c3bf3f
Autor:
Yuichi Kojima, Atsunori Tsuchiya, Masaki Mito, Yusuke Watanabe, Yuzo Kawata, Kentaro Tominaga, Shuji Terai
Publikováno v:
JGH Open, Vol 8, Iss 8, Pp n/a-n/a (2024)
Abstract Background and Aim Neutrophil gelatinase‐associated lipocalin (NGAL) is characterized by increased expression before the rise in serum creatinine and has been used as a biomarker for the early prediction of acute kidney injury (AKI). Howev
Externí odkaz:
https://doaj.org/article/a8f9ae5513594a7a9a0cfab1507a6563
Autor:
Kenji Suzuki, Yukinori Sameshima, Junji Yokoyama, Shuji Terai, Hiroyuki Yoneyama, Raja Atreya, Markus F. Neurath, Toshifumi Hibi, Hitoshi Asakura
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-10 (2024)
Abstract Background Carbohydrate sulfotransferase 15 (CHST15) is an enzyme biosynthesizing matrix glycosaminoglycan that modulates tissue remodeling. We evaluated the efficacy of add-on submucosal injections of GUT-1, the RNA oligonucleotide inhibito
Externí odkaz:
https://doaj.org/article/4d12c4d2ddc145778e89ea6704cc7480
Autor:
Suguru Miida, Yoshihisa Arao, Nobutaka Takeda, Shu Goto, Yuichi Kojima, Naruhiro Kimura, Kazunao Hayashi, Atsunori Tsuchiya, Shuji Terai
Publikováno v:
DEN Open, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract Several cases of esophageal stenosis caused by cervical vertebral osteophytes have been reported; however, few reports of esophageal stenosis caused by thoracic osteophytes are available. We describe the case of an 86‐year‐old man with e
Externí odkaz:
https://doaj.org/article/19743012aaa542a6b2ac8897f47222b9
Publikováno v:
Livers, Vol 3, Iss 4, Pp 562-568 (2023)
Aim: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. Pemafibrate, a selective peroxisome-proliferator-activated receptor α modulator (SPPARMα), has been reported to ameliorate liver function among patien
Externí odkaz:
https://doaj.org/article/d2ce1b280a364a479ae1fd5841269295
Autor:
Nobutaka Takeda, Atsunori Tsuchiya, Masaki Mito, Kazuki Natsui, Yui Natusi, Yohei Koseki, Kei Tomiyoshi, Fusako Yamazaki, Yuki Yoshida, Hiroyuki Abe, Masayuki Sano, Taketomo Kido, Yusuke Yoshioka, Junichi Kikuta, Tohru Itoh, Ken Nishimura, Masaru Ishii, Takahiro Ochiya, Atsushi Miyajima, Shuji Terai
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-14 (2023)
Abstract Background The progression of liver fibrosis leads to portal hypertension and liver dysfunction. However, no antifibrotic agents have been approved for cirrhosis to date, making them an unmet medical need. Small extracellular vesicles (sEVs)
Externí odkaz:
https://doaj.org/article/33ffc1abeeee43bea1671cd58272c823
Autor:
Masaki Maruyama, Suguru Miida, Toshihiro Sato, Takazumi Kimura, Azuma Watanabe, Hideo Watanabe, Masafumi Nishizawa, Kyohei Horikawa, Takahiro Kajiwara, Yusuke Karasawa, Yuko Hasebe, Kazutaka Nozawa, Shuji Terai
Publikováno v:
JGH Open, Vol 7, Iss 9, Pp 610-617 (2023)
Abstract Background and Aim Stimulant laxatives may cause electrolyte abnormalities, dehydration, and abdominal pain; their long‐term use can lead to tolerance and subsequent refractory constipation. We investigated the effectiveness, safety, and q
Externí odkaz:
https://doaj.org/article/a859dfd9f6cc48efa567bebe5ac1dc2a
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5454 (2024)
The human genome encodes at least 500 protein kinases, and among them, there are at least 90 tyrosine kinases [...]
Externí odkaz:
https://doaj.org/article/240040dca2624f34b6e15d45b23d9214
Autor:
Hiroyuki Abe, Kenya Kamimura, Shujiro Okuda, Yu Watanabe, Jun Inoue, Yutaka Aoyagi, Toshifumi Wakai, Ryo Kominami, Shuji Terai
Publikováno v:
Cancer Medicine, Vol 12, Iss 14, Pp 15650-15663 (2023)
Abstract Introduction B‐cell lymphoma/leukemia 11B (BCL11B) is a subunit of SWI/SNF chromatin remodeling complexes and functions in cell cycle regulation and apoptosis upon DNA replication stress and damages via transcription. Many malignancies wer
Externí odkaz:
https://doaj.org/article/b28136d80b664370b096168307a180cc