Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shuji Kaga"'
Autor:
Seiji Minota, Yasunori Yamaguchi, Shuji Kaga, Yasunori Uemura, Toshiyuki Tanaka, Yoshiaki Sohma, Tetsuto Kobayashi, Kaori Horie, Hiroko Inazawa, Jun-Ichi Masuyama, Kumiko Kojima, Yumi Aoki, Isao Serizawa, Tomoko Watanabe
Publikováno v:
Clinical Immunology. 120:247-259
We previously reported that 4C8 monoclonal antibody (mAb) provides a costimulatory signal to human CD4+ T cells and consequently induces regulatory T (Treg) cells, which are hypo-responsive and suppress the polyclonal response of bystander CD4+ cells
Publikováno v:
The Journal of Immunology. 161:1390-1398
This communication describes an extracellular signal-regulated kinase kinase (MEK)-dependent signal transduction pathway that prevents the terminal differentiation of a hemopoietic cell line. Both PMA and the cell-permeable ceramide, C2-ceramide, cau
Publikováno v:
The Journal of Immunology. 160:24-27
Unless a costimulatory signal is provided, TCR recognition of Ag bound to the MHC is insufficient to induce optimal T cell proliferation or the production of IL-2. Here we show that the stimulation of CD28, a T cell costimulatory receptor, by a speci
Autor:
Noriko Yamagata, Keita Kasahara, Shuji Kaga, Kazuo Kobayashi, Hideaki Iwabuchi, Terumi Takahashi, Tsuyoshi Kasama, Sachiko Sugihara, Takashi Katsura
Publikováno v:
Ensho. 12:475-480
Granulomas are focal, predominantly mononuclear tissue inflammations evoked by persistent irritants. Granulomatous inflammation can be classified as either a hypersensitive type (immunologic) or a foreign-body type (non-immunologic) response. The com
Autor:
Masao Negishi, Noriko Yamagata, K. Nakatani, Tsuyoshi Kasama, Shuji Kaga, Terumi Takahashi, Hirotsugu Ide, Yukie Niwa, Kazuo Kobayashi, H. Kanemitsu
Publikováno v:
Immunology Letters. 26:171-175
To explore the role of interleukins in development of arthritis, we induced collagen-induced arthritis in mice and examined interleukin activities in the inflamed joints. Arthritis developed in 90% of mice 4–5 weeks after primary immunization with
[A case with systemic lupus erythematosus presenting with reversible edematous lesion in cerebellum]
Autor:
Michio, Hanyuda, Yoshiyuki, Yoda, Takayuki, Shiozawa, Ryosuke, Hanaoka, Yusuke, Miwa, Shuji, Kaga, Takeshi, Kasama, Masao, Negishi, Hirotsugu, Ide
Publikováno v:
Ryumachi. [Rheumatism]. 42(5)
We report the case of a 24-year-old woman with systemic lupus erythematosus (SLE). The patient presented with cervical erythema and multiple arthralgia in December, 1996. Based on the high level of antinuclear antibody and the positivity for anti-dou
Autor:
Yusuke, Miwa, Shuji, Kaga, Ryosuke, Hanaoka, Fumitaka, Shiozawa, Michio, Hanyuda, Tsuyoshi, Kasama, Masao, Negishi, Hirotsugu, Ide
Publikováno v:
Ryumachi. [Rheumatism]. 42(1)
A 70-year-old female was diagnosed as having rheumatoid arthritis (RA) in 1971, which was then treated with steroid and nonsteroidal anti-inflammatory drugs. In 1999, after total replacement of her knee joint, 4 mg of methotrexate (MTX) per week was
Autor:
Keita Kasahara, Tsuyoshi Kasama, Noriko Yamagata, Terumi Takahashi, Kazue Yoshida, Kazuko Nakatani, Hiroko Takeuchi, Shuji Kaga, Kazuo Kobayashi, Tomoko Matsuda
Publikováno v:
International archives of allergy and applied immunology. 95(2-3)
Foreign-body (dextran beads) and hypersensitivity (antigen-coupled agarose beads) lung granulomas were induced in BALB/c mice by the intratracheal injection of beads. Large granulomas developed, which reached peak intensity within 3 days and declined
Autor:
Ikuyo Sato, E Skamene, Keita Kasahara, Kazuo Kobayashi, Shuji Kaga, R M Nakamura, Tsuyoshi Kasama, H. Kanemitsu, Terumi Takahashi, K. Nakatani
Publikováno v:
Infection and immunity. 58(5)
Natural bactericidal resistance to Mycobacterium bovis BCG is under the control of a single gene, designated Bcg. Lung granuloma formation in susceptible (Bcgs) and resistant (Bcgr) mice was studied in two sets of Bcg-congenic systems, namely, the BA
Autor:
Kazuhiko Soejima, Takeshi Yoshida, Keita Kasahara, Yusuke Shikama, Shuji Kaga, Hirotsugu Ide, Terumi Takahashi, Ikuyo Yoneya, Mikio Hashimoto, Toji Odagiri, Kazuo Kobayashi
Publikováno v:
Clinical Immunology and Immunopathology. 51:419-425
Granulomatous inflammation is associated with many significant human diseases, including tuberculosis, leprosy, sarcoidosis, parasite infection, and berylliosis. Very little is known about the basic mechanism of this type of inflammation. In the pres