Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Shuizhen Shi"'
Autor:
Seth E. Buscho, Fan Xia, Shuizhen Shi, Jonathan L. Lin, Bartosz Szczesny, Wenbo Zhang, Massoud Motamedi, Hua Liu
Publikováno v:
Cells, Vol 12, Iss 23, p 2685 (2023)
Optic neuritis, a characteristic feature of multiple sclerosis (MS), involves the inflammation of the optic nerve and the degeneration of retinal ganglion cells (RGCs). Although previous studies suggest that retinal blood flow alterations occur durin
Externí odkaz:
https://doaj.org/article/d94fc70cd9cc4a36a3326b6a983a31dc
Autor:
Yi Li, Shuizhen Shi, Fan Xia, Chao Shan, Yonju Ha, Jing Zou, Awadalkareem Adam, Ming Zhang, Tian Wang, Hua Liu, Pei-Yong Shi, Wenbo Zhang
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Zika virus (ZIKV), a mosquito-borne flavivirus, can cause severe eye disease and even blindness in newborns. However, ZIKV-induced retinal lesions have not been studied in a comprehensive way, mechanisms of ZIKV-induced retinal abnormalities
Externí odkaz:
https://doaj.org/article/c1dba2717344461db167f19f4c36753e
Autor:
Fan Xia, Yonju Ha, Shuizhen Shi, Yi Li, Shengguo Li, Jonathan Luisi, Rakez Kayed, Massoud Motamedi, Hua Liu, Wenbo Zhang
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract The retina, as the only visually accessible tissue in the central nervous system, has attracted significant attention for evaluating it as a biomarker for neurodegenerative diseases. Yet, most of studies focus on characterizing the loss of r
Externí odkaz:
https://doaj.org/article/5c451ee287c14a679682b2c9123dccfb
Autor:
Huanle Luo, Guangyu Li, Binbin Wang, Bing Tian, Junling Gao, Jing Zou, Shuizhen Shi, Shuang Zhu, Bi-Hung Peng, Awadalkareem Adam, Ariza Martinez, Kimberly Hein, Evandro R Winkelmann, Yoseph Mahmoud, Xiaofei Zhou, Chao Shan, Shannan Rossi, Scott Weaver, Alan D T Barrett, Shao-Cong Sun, Wenbo Zhang, Pei-Yong Shi, Ping Wu, Tian Wang
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008538 (2020)
Zika virus (ZIKV) infects pregnant women and causes devastating congenital zika syndrome (CZS). How the virus is vertically transmitted to the fetus and induces neuronal loss remains unclear. We previously reported that Pellino (Peli)1, an E3 ubiquit
Externí odkaz:
https://doaj.org/article/e6aaf087f9c54d1ebedc84ee5fae74d3
Autor:
Jimin Xu, Shuizhen Shi, Gang Liu, Xuping Xie, Jun Li, Andrew A. Bolinger, Haiying Chen, Wenbo Zhang, Pei-Yong Shi, Hua Liu, Jia Zhou
Publikováno v:
European journal of medicinal chemistry. 246
Sirt6 activation has emerged as a promising drug target for the treatment of various human diseases, while only limited Sirt6 activators have been reported. Herein, a series of novel pyrrolo[1,2-a]quinoxaline-based derivatives have been identified as
Autor:
Yonju, Ha, Lorenzo F, Ochoa, Olivia, Solomon, Shuizhen, Shi, Paula P, Villarreal, Shengguo, Li, Seth, Buscho, Gracie, Vargas, Wenbo, Zhang
Publikováno v:
EC Ophthalmol
PURPOSE: Optic nerve degeneration is a feature of neurodegenerative eye diseases and causes irreversible vision loss. Therefore, understanding the degenerating patterns of the optic nerve is critical to find the potential therapeutic target for optic
Autor:
Shengguo Li, Shuizhen Shi, Ban Luo, Fan Xia, Yonju Ha, Jonathan Luisi, Praveena K. Gupta, Kevin H. Merkley, Massoud Motamedi, Hua Liu, Wenbo Zhang
Publikováno v:
Experimental eye research. 225
Corneal neovascularization can cause devastating consequences including vision impairment and even blindness. Corneal inflammation is a crucial factor for the induction of corneal neovascularization. Current anti-inflammatory approaches are of limite
Autor:
Wenbo Zhang, Tian Wang, Hua Liu, Shuizhen Shi, Yi Li, Fan Xia, Yonju Ha, Pei Yong Shi, Jing Zou, Ming Zhang, Awadalkareem Adam, Chao Shan
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Zika virus (ZIKV), a mosquito-borne flavivirus, can cause severe eye disease and even blindness in newborns. However, ZIKV-induced retinal lesions have not been studied in a comprehensive way, mechanisms of ZIKV-induced retinal abnormalities are unkn
Autor:
Jia Zhou, Jimin Xu, Shuizhen Shi, Gang Liu, Xuping Xie, Jun Li, Andrew A. Bolinger, Haiying Chen, Wenbo Zhang, Pei-Yong Shi, Hua Liu
Publikováno v:
SSRN Electronic Journal.
Autor:
Seth Buscho, Erick Palacios, Fan Xia, Shuizhen Shi, Shengguo Li, Jonathan Luisi, Rakez Kayed, Massoud Motamedi, Wenbo Zhang, Hua Liu
Publikováno v:
Experimental Eye Research. 224:109240
Tauopathies are a family of neurodegenerative diseases which predominately afflict the rapidly growing aging population suffering from various brain disorders including Alzheimer's disease, frontotemporal dementia with parkinsonism-17 and Pick diseas