Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Shuishen Zhang"'
Autor:
Hui Han, Yucong Sun, Wei Wei, Zixin Huang, Maosheng Cheng, Hongshen Qiu, Juan Wang, Siyi Zheng, Lianlian Liu, Qiang Zhang, Canfeng Zhang, Jieyi Ma, Siyao Guo, Zhaoyu Wang, Zhenpeng Li, Xu Jiang, Shuibin Lin, Qianwen Liu, Shuishen Zhang
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109327- (2024)
Summary: Emerging studies have demonstrated the link between RNA modifications and various cancers, while the predictive value and functional mechanisms of RNA modification-related genes (RMGs) in esophageal squamous cell carcinoma (ESCC) remain uncl
Externí odkaz:
https://doaj.org/article/d26ae0dca59d488eb95f86eb65e7e171
Autor:
Bingbing Feng, Xinying Wang, Ding Qiu, Haiyang Sun, Jianping Deng, Ying Tan, Kaile Ji, Shaoting Xu, Shuishen Zhang, Ce Tang
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4953 (2024)
Lung adenocarcinoma (LUAD) is the most prevalent and aggressive subtype of lung cancer, exhibiting a dismal prognosis with a five-year survival rate below 5%. DEAD-box RNA helicase 18 (DDX18, gene symbol DDX18), a crucial regulator of RNA metabolism,
Externí odkaz:
https://doaj.org/article/c69576a5350142b3bd450b13da141f54
Autor:
Wei Wei, Shuishen Zhang, Hui Han, Xiaochen Wang, Siyi Zheng, Zhaoyu Wang, Chunlong Yang, Lu Wang, Jieyi Ma, Siyao Guo, Juan Wang, Lianlian Liu, Junho Choe, Shuibin Lin
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112810- (2023)
Summary: Aberrant RNA modifications are frequently associated with cancers, while the underlying mechanisms and clinical significance remain poorly understood. Here, we find that the ac4C RNA acetyltransferase NAT10 is significantly upregulated in es
Externí odkaz:
https://doaj.org/article/a3f40575b2bb45beac269ae22cbdc878
Autor:
Shuyue Zhang, Shuishen Zhang, Xiaofan Ma, Jing Zhan, Chuqing Pan, Huizhong Zhang, Xiuying Xie, Jing Wen, Xuan Xie
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundDifferent intratumoral microbiotaexist in different tumors and play a crucial function in carcinogenesis. However, whether they impact clinical outcomes in esophageal squamous cell carcinoma (ESCC) and their mechanism remain unclear.Methods
Externí odkaz:
https://doaj.org/article/fb56541eb74448da960a5165af1819eb
Autor:
Shuishen Zhang, Qianwen Liu, Bin Li, Minghan Jia, Xiaoli Cai, Weixiong Yang, Shufen Liao, Zhongkai Wu, Chao Cheng, Jianhua Fu
Publikováno v:
Cancer Medicine, Vol 11, Iss 7, Pp 1617-1629 (2022)
Abstract Background The survival benefits of recurrent laryngeal nerve lymph node dissection (RLNLD) in esophageal squamous cell carcinoma (ESCC) are still under debate, and the prognostic value of unilateral RLNLD has been rarely studied. Therefore,
Externí odkaz:
https://doaj.org/article/100f0f4865bf47109cfd495f9807cc95
Autor:
Hui Han, Chunlong Yang, Jieyi Ma, Shuishen Zhang, Siyi Zheng, Rongsong Ling, Kaiyu Sun, Siyao Guo, Boxuan Huang, Yu Liang, Lu Wang, Shuang Chen, Zhaoyu Wang, Wei Wei, Ying Huang, Hao Peng, Yi-Zhou Jiang, Junho Choe, Shuibin Lin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Deregulation of METTL1-mediated N7- methylguanosine tRNA modification can promote oncogenesis. Here, the authors report that this modification regulates the translation of proteins in both the mTOR and negative regulators of autophagy pathways, resul
Externí odkaz:
https://doaj.org/article/f2ee912cfd1b4d88a341d2e5aa7507df
Autor:
Hui Han, Chunlong Yang, Shuishen Zhang, Maosheng Cheng, Siyao Guo, Yan Zhu, Jieyi Ma, Yu Liang, Lu Wang, Siyi Zheng, Zhaoyu Wang, Demeng Chen, Yi-Zhou Jiang, Shuibin Lin
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 333-346 (2021)
Esophageal cancer is a lethal malignancy with a high mortality rate, while the molecular mechanisms underlying esophageal cancer pathogenesis are still poorly understood. Here, we found that the N6-methyladenosine (m6A) methyltransferase-like 3 (METT
Externí odkaz:
https://doaj.org/article/f647afb633ac4c929f84408825892366
Autor:
Shuishen Zhang, Junying Chen, Bin Li, Xiaoli Cai, Kexi Wang, Zihui Tan, Yuzhen Zheng, Qianwen Liu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Lay summaryPatients with a family history of cancer, especially digestive tract cancer and esophageal cancer, a family history of cancer in the first degree, and more than one relative affected by cancer were associated with favorable survival when c
Externí odkaz:
https://doaj.org/article/b7aeb6d131174d97a50ac26556e21393
Autor:
Jing Wen, Yi Hu, Qianwen Liu, Yihong Ling, Shuishen Zhang, Kongjia Luo, Xiuying Xie, Jianhua Fu, Hong Yang
Publikováno v:
EBioMedicine, Vol 37, Iss , Pp 110-124 (2018)
Background: Dysregulation of the cell cycle has been implicated in esophageal squamous cell carcinoma (ESCC) progression. This study aimed to evaluate the role of miR-424 in cell cycle regulation and ESCC proliferation. Methods: The role of miR-424 i
Externí odkaz:
https://doaj.org/article/d02a3d464f9e425e8af6142b09cf6385
Autor:
Chuqing Pan, Yu Wang, Qianwen Liu, Yihuai Hu, Jianhua Fu, Xiuying Xie, Shuishen Zhang, Mian Xi, Jing Wen
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
The tumor microenvironment (TME) of esophageal squamous cell carcinoma (ESCC) impacts tumor progression but is poorly understood. We obtained tumor tissues from 279 patients after esophagectomy and characterized the TME in intraepithelial and stromal
Externí odkaz:
https://doaj.org/article/040dcf76fa834146b980ca7cbc08c330