Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Shuiming Qian"'
Autor:
Shuiming Qian, Xinchen Lv, Ray N. Scheid, Li Lu, Zhenlin Yang, Wei Chen, Rui Liu, Melissa D. Boersma, John M. Denu, Xuehua Zhong, Jiamu Du
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Histone mark reader proteins bind to particular histone modifications and regulate chromatin state. Here, Qian et al. show that the SHORT LIFE reader has a unique ability to recognize both activating and repressive histone marks and that these intera
Externí odkaz:
https://doaj.org/article/a2b07e6441f747e1b89d2d59f77e7bb2
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The canonical histone variant H3.1 of vascular plants contains a conserved Phe residue at position 41 that is unique to the plant kingdom. Here, Lu et al. provide evidence that H3.1Phe41 acts collaboratively with the H3.1 core domain to restrict H3.1
Externí odkaz:
https://doaj.org/article/13ba31fd706f48e19bb774e356cf46e0
Autor:
Xiangsong Chen, Li Lu, Kevin S Mayer, Mark Scalf, Shuiming Qian, Aaron Lomax, Lloyd M Smith, Xuehua Zhong
Publikováno v:
eLife, Vol 5 (2016)
Leaf senescence is an essential part of the plant lifecycle during which nutrients are re-allocated to other tissues. The regulation of leaf senescence is a complex process. However, the underlying mechanism is poorly understood. Here, we uncovered a
Externí odkaz:
https://doaj.org/article/01b7173245d04a138698363d1dabef2b
Autor:
Jie Liu, Jianjun Jiang, Zhihua Hua, Fengquan Liu, Xuehua Zhong, Giovanna Serino, Shuiming Qian, Jiani Chen, Isabel Delo, Rachel Kabara, Jingwen Song
Publikováno v:
New Phytol
DNA methylation plays crucial roles in cellular development and stress responses through gene regulation and genome stability control. Precise regulation of DOMAINS REARRANGED METHYLTRANSFERASE 2 (DRM2), the de novo Arabidopsis DNA methyltransferase,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4759a84a6fcfe827a2159120f3af9f
https://doi.org/10.1111/nph.17103
https://doi.org/10.1111/nph.17103
Autor:
Jie Liu, Fengquan Liu, Jianjun Jiang, Jikui Song, Wendan Ren, Dean Sanders, Xuehua Zhong, Shuiming Qian
Publikováno v:
Nature plants, vol 7, iss 2
Nature plants
Nature plants
DNA methylation is an important epigenetic gene regulatory mechanism conserved in eukaryotes. Emerging evidence shows DNA methylation alterations in response to environmental cues. However, the mechanism of how cells sense these signals and reprogram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41d9441d86241051d31b52017afb25e
https://escholarship.org/uc/item/5p57g79k
https://escholarship.org/uc/item/5p57g79k
Autor:
Yun Zhou, Jingfang Zhang, Erik A. Ranheim, Eric Padron, Xiaona You, Christopher Letson, Jing Zhang, Xuehua Zhong, Mignon L. Loh, Elliot Stieglitz, Shuiming Qian, Lan Zhou, Warren S. Pear, Yangang Liu, Zhi Wen, Xinmin Zhang, Yuan I. Chang, David T. Yang, Guangyao Kong, Adhithi Rajagopalan, Inga Hofmann
Publikováno v:
Leukemia
The Notch signaling pathway contributes to the pathogenesis of a wide spectrum of human cancers, including hematopoietic malignancies. Its functions are highly dependent on the specific cellular context. Gain-of-function NOTCH1 mutations are prevalen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe99f155ed2bbc4141f14bf371881226
https://doi.org/10.1038/s41375-018-0248-0
https://doi.org/10.1038/s41375-018-0248-0
Autor:
Ray N. Scheid, Jiamu Du, Lloyd M. Smith, Shuiming Qian, John M. Denu, Xinchen Lv, Zhilin Yang, Xuehua Zhong, Xiongming Du, Xiangsong Chen, Mark Scalf, Rui Liu, Lei Lu, Boersma
Publikováno v:
Nature Genetics. 50:1247-1253
The ability of cells to perceive and translate versatile cues into differential chromatin and transcriptional states is critical for many biological processes1-5. In plants, timely transition to a flowering state is crucial for successful reproductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49489bd8bb4261f7cf0eb56b8f10c6e1
https://doi.org/10.1038/s41588-018-0187-8
https://doi.org/10.1038/s41588-018-0187-8
Autor:
Xinchen Lv, Ray N. Scheid, Jiamu Du, Rui Liu, Shuiming Qian, Xuehua Zhong, Melissa D. Boersma, Li Lu, Wei Chen, John M. Denu, Zhenlin Yang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
The ability of a cell to dynamically switch its chromatin between different functional states constitutes a key mechanism regulating gene expression. Histone mark “readers” display distinct binding specificity to different histone modifications a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7dd124747c0d5610c9ca21ee89f6b7
https://doaj.org/article/a2b07e6441f747e1b89d2d59f77e7bb2
https://doaj.org/article/a2b07e6441f747e1b89d2d59f77e7bb2
Publikováno v:
The Plant Cell. 30:134-152
Ribosome biogenesis is a fundamental process required for all cellular activities. Histone deacetylases play critical roles in many biological processes including transcriptional repression and rDNA silencing. However, their function in pre-rRNA proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a3049da481eceade5026dd3f929880
https://doi.org/10.1105/tpc.17.00626
https://doi.org/10.1105/tpc.17.00626
Histone Lysine-to-Methionine Mutations Reduce Histone Methylation and Cause Developmental Pleiotropy
Autor:
John M. Denu, Shuiming Qian, Rachael Fieweger, James A. Dowell, Dean Sanders, Li Lu, Xuehua Zhong
Publikováno v:
Plant Physiology. 173:2243-2252
Epigenetic modifications play critical roles in diverse biological processes. Histone Lys-to-Met (K-to-M) mutations act as gain-of-function mutations to inhibit a wide range of histone methyltransferases and are thought to promote tumorigenesis. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a89195d7b21a142b5b76dc6c1319501b
https://doi.org/10.1104/pp.16.01499
https://doi.org/10.1104/pp.16.01499