Rational screening of peroxisome proliferator-activated receptor-γ agonists from natural products: potential therapeutics for heart failure

Autor: Rui Chen, Jing Wan, Jing Song, Yan Qian, Yong Liu, Shuiming Gu

Publikováno v: Pharmaceutical Biology, Vol 55, Iss 1, Pp 503-509 (2017)

Context: Peroxisome proliferator-activated receptor-γ (PPARγ) is a member of the nuclear hormone receptor superfamily of ligand-activated transcription factors. Activation of PPARγ pathway has been shown to enhance fatty acid oxidation, improve en

Externí odkaz: https://doaj.org/article/7e24b9b80aa04d3da388871e7e2b57f1

Cycle threshold values are not associated with mortality: Risk factor analysis in older patients with the SARS-CoV-2 Omicron variant

Autor: Ya Wu, Yunhai Feng, Jing Wan, Wei Du, Minfang Tao, Shuiming Gu, Jun Yin

Publikováno v: Travel Medicine and Infectious Disease. 52:102555

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d226cbf96d9d83cb8dcfd42927628c1b
https://doi.org/10.1016/j.tmaid.2023.102555

Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial

Autor: Rury R Holman, Ruth L Coleman, Juliana C N Chan, Jean-Louis Chiasson, Huimei Feng, Junbo Ge, Hertzel C Gerstein, Richard Gray, Yong Huo, Zhihui Lang, John J McMurray, Lars Rydén, Stefan Schröder, Yihong Sun, Michael J Theodorakis, Michal Tendera, Lynne Tucker, Jaakko Tuomilehto, Yidong Wei, Wenying Yang, Duolao Wang, Dayi Hu, Changyu Pan, Joanne Keenan, Joanne Milton, Zoe Doran, Chris Bray, Jean L Rouleau, Jane Collier, Stuart Pocock, Eberhard Standl, Karl Swedberg, Jianping Weng, Dong Zhao, Mark C Petrie, Eugene Connolly, Pardeep Jhund, Michael MacDonald, Rachel C Myles, Rong Bai, Jing Li, Zhaoping Liu, Zhenyu Liu, Dantao Peng, Qiguang Tong, Chunxue Wang, Xiaowei Yan, Yuqing Zhang, Jingmin Zhou, Naveed Sattar, Miles Fisher, John R Petrie, M Angelyn Bethel, Wen Xu, Sarah Hearn, Anurag Kappai, Shu-Yi Su, Winitha Liyanage, Sanjoy Paul, Emanuela Pozzi, Arne Ring, Rajbir Athwal, Priyanka Batra, Andrea Ferch, Natasha Groves, Irene Kennedy, Olga Nawalaniec, Yash Patel, Rachel Roberts, Victoria Rush, Jayne Starrett, Jennifer Tang, Jing Bi, Zhe Jiang, Hua Wei, Xiaoshuai Wei, Xuan Zhang, Jun Yin, Yu Sun, Rong Hu, Yang Liu, Jianjing Long, Yuefeng Long, Guofang Qiao, Haoyi Qiao, Xiaochun Sun, Yucheng Zhang, Jing Zhou, Bangning Wang, Bin Chen, Lili Deng, Xiaoning Han, Taohong Hu, Qi Hua, Yanming Huo, Hongmei Li, Hongwei Li, Lihua Liu, Juming Lu, Changsheng Ma, Jianjun Peng, Lin Pi, Bin Wang, Guanglin Wei, Ming Yang, Shuyang Zhang, Likun Zhang, Xia Zhao, Yujie Zhou, Libin Shi, Mingsheng Wang, Lirong Wu, Lei Han, Ronghong Liao, Boli Ran, Qiang She, Jiancong Tan, Mei Xia, Chengming Yang, Lianglong Chen, Shangquan Xiong, Ling Yu, Xiaodong Pu, Yan Wang, Qiang Xie, Cibin Chen, Jiyan Chen, Yugang Dong, Zhaohui Wu, Yong Yuan, Wanxing Zhou, Shuxian Zhou, Xiaochao Chen, Chun Wu, Aidong Zhang, Zicheng Li, Shayi Lai, Jin Yang, Jinru Wei, Riyu Kuang, Zilin Zhao, Guoqiang Zhong, Xufen Cao, Yuming Hao, Gang Liu, Dongmei Wang, Hui Fang, Lingjun Kong, Haitao Li, Changqing Wang, Li'na Wang, Xueqi Li, Pingshuan Dong, Shouyan Zhang, Xincan Liu, Yulan Zhao, Hengliang Liu, Ye Gu, Yuhua Liao, Xi Su, Daowen Wang, Hairong Wang, Bo Yang, Ying Guo, Ding'an Ouyang, Tianlun Yang, Yumin Zhang, Yajun Han, Xuefeng Lin, Ruiping Zhao, Ronghai Man, Rongwen Bian, Xu Biao, Buaijiaer Hasimu, Hui Jin, Ping Liu, Jiangyi Yu, Hang Zhang, Chongli Xu, Yan Guo, Ke Lv, Yijia Tao, Xin Xu, Zhenyu Yang, Dongye Li, Chunmei Qi, Guohui Zhang, Xiang Gu, Lang Hong, Ling Hu, Juxiang Li, Ping Yang, Bin Liu, Gang Wang, Hailong Lin, Jun Liu, Shuying Zhang, Ping Han, Yuanzhe Jin, Ling Li, Zhanquan Li, Hong Luan, Mei Song, Li Xue, Yu Hua, Dongwu Liu, Zuyi Yuan, Jixian Ye, Feng Gao, Jinhua Feng, A'li Wang, Shengming Ye, Xiaoyan Li, Guohai Su, Shufang Zhang, Zishan Hou, Wenbin Jiang, Changyong Zhou, Yanping Wang, Wenbo Qi, Xiaomei Bao, Bo Feng, Hui Gong, Shuiming Gu, Mingjun Gu, Xingui Guo, Ben He, Ying Huang, Jinfa Jiang, Yifeng Jiang, Huigen Jin, Yuehua Li, Qiliang Liu, Guoping Lu, Peizhi Miao, Yongwen Qin, Yuanming Wang, Shiyao Wu, Yawei Xu, Jin Ma, Xiaoping Chen, Xiumin Liu, Jianing Tang, Jingping Wang, Jianhong Tao, Jun Zhang, Tingjie Zhang, Decai Li, Xinping Du, Tiemin Jiang, Jingna Lin, Chengzhi Lu, Hongjun Ma, Bo Gao, Xukun Guo, Tong Li, Shaoxiong Zheng, Zhongcheng Li, Shuwu Zhao, Qiang Qiu, Kaili Li, Junming Liu, Baopeng Tang, Zhanjun Yuan, Jianhua Zhou, Wenwei Bai, Tao Guo, Ge Zhang, Hong Zhang, Yinglu Hao, Guosheng Fu, Lijiang Tang, Jialun Chen

Publikováno v: Lancet Diabetes and endocrinology. 5(11)

Background The effect of the α-glucosidase inhibitor acarbose on cardiovascular outcomes in patients with coronary heart disease and impaired glucose tolerance is unknown. We aimed to assess whether acarbose could reduce the frequency of cardiovascu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcfa097b75afcc57b4458801c676f89
http://ora.ox.ac.uk/objects/uuid:

Therapeutic monitoring of serum digoxin for patients with heart failure using a rapid LC-MS/MS method

Autor: Chen Yu, Xueying Shi, Yiping Wang, Shuijun Li, Peizhi Miao, Yi Miao, Shuiming Gu, Gangyi Liu, Jingying Jia

Publikováno v: Clinical Biochemistry. 43:307-313

Objective Here we develop a liquid chromatography tandem mass spectrometry (LC-MS/MS) method for the determination of digoxin in serum. Design and methods The serum samples were extracted with methyl tert-butyl ether using an isotope-labeled digoxin-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc50c729104af81b075ab7d587545ff
https://doi.org/10.1016/j.clinbiochem.2009.09.025

Plasma Lp-PLA2 in acute coronary syndrome: association with major adverse cardiac events in a community-based cohort

Autor: Shuiming Gu, Shuijun Li, Ning Li, Chen Yu

Publikováno v: Postgraduate medicine. 122(4)

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a useful inflammatory marker of cardiovascular risk, yet there are few reports on the prognostic significance of Lp-PLA2 as a risk factor for acute coronary syndrome (ACS). It is necessary to evalu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b6dbe02c8d5c01ce4329872da1885f
https://pubmed.ncbi.nlm.nih.gov/20675983