Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Shuijun Zhang"'
Autor:
Hongwei Tang, Qiwen Yu, Xu Chen, Jiakai Zhang, Danfeng Guo, Wenzhi Guo, Shuijun Zhang, Xiaoyi Shi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Although the death of hepatocytes is a crucial trigger of liver ischemia–reperfusion (I/R) injury, the regulation of liver I/R-induced hepatocyte death is still poorly understood. Phosphoglycerate mutase 5 (PGAM5), a mitochondrial Serine/T
Externí odkaz:
https://doaj.org/article/b556793379844f09b33c6ddd69f02787
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Hepatocellular carcinoma (HCC) is the third leading cause of global cancer-related deaths. Despite immunotherapy offering hope for patients with HCC, only some respond to it. However, it remains unclear how to pre-screen eligible patients. O
Externí odkaz:
https://doaj.org/article/d27a7048281d46f49d22db348e96b464
Autor:
Long Liu, Jie Gao, Xudong Liu, Feng Zhang, Bowen Hu, Huapeng Zhang, Zhihui Wang, Hongwei Tang, Ji Hua Shi, Shuijun Zhang
Publikováno v:
Cancer Medicine, Vol 12, Iss 23, Pp 21531-21544 (2023)
Abstract Introduction The mitochondrial alanyl‐tRNA synthetase 2 (AARS2) as one of aminoacyl‐tRNA synthases (ARSs) performs amino acid transportation and involves protein synthesis. However, its role in cancer remains largely unexplored. Methods
Externí odkaz:
https://doaj.org/article/9ec0052af322451c917dac0b0f34a96b
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-37 (2023)
Abstract Non-coding RNA has aroused great research interest recently, they play a wide range of biological functions, such as regulating cell cycle, cell proliferation, and intracellular substance metabolism. Piwi-interacting RNAs (piRNAs) are emergi
Externí odkaz:
https://doaj.org/article/eacc95ab9aa8405d946d718b4a9153f8
Publikováno v:
Materials & Design, Vol 239, Iss , Pp 112812- (2024)
Surgical site infection (SSI) is a feared complication in liver resection. Developing wound dressings that effectively combat bacterial infection and promote tissue regeneration is clinically significant. Herein, we present a near-infrared (NIR) ligh
Externí odkaz:
https://doaj.org/article/43aa04e5af5b42c59af1ccabf6492f8a
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Mitogen activated protein kinase phosphatase 5 (MKP5) is a member of the MKP family and has been implicated in diverse biological and pathological conditions. However, it is unknown what role MKP5 plays in liver ischemia/reperfusion (I/R) in
Externí odkaz:
https://doaj.org/article/e61b9a8adf9444f1a7be35415d61689a
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-17 (2023)
Abstract Hepatic ischemia-reperfusion (I/R) injury, a common clinical complication of liver transplantation, gravely affects patient prognosis. Krüppel-like factors (KLFs) constitute a family of C2/H2 zinc finger DNA-binding proteins. KLF6, a member
Externí odkaz:
https://doaj.org/article/85a9b73d395b48f8afb287a6819cd969
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Intratumoral microbial communities have been recently discovered to exist in a variety of cancers and have been found to be intricately involved in tumour progression. Therefore, investigating the profiles and functions of intratu
Externí odkaz:
https://doaj.org/article/d97418ad5bec46e681b87ba8db633c26
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The epithelial sodium channel (ENaC) is a heterotrimer and is widely distributed throughout the kidneys, blood vessels, lungs, colons, and many other organs. The basic role of the ENaC is to mediate the entry of Na+ into cells; the ENaC also has an i
Externí odkaz:
https://doaj.org/article/d1ee9d49879c4fa99975ed74e8f29e8d
Fluid shear stress induces cell migration via RhoA-YAP1-autophagy pathway in liver cancer stem cells
Autor:
Zhiping Yan, Danfeng Guo, Ruolin Tao, Xiao Yu, Jiacheng Zhang, Yuting He, Jiakai Zhang, Jie Li, Shuijun Zhang, Wenzhi Guo
Publikováno v:
Cell Adhesion & Migration, Vol 16, Iss 1, Pp 94-106 (2022)
Fluid shear stress (FSS) regulates the metastasis of hepatocellular carcinoma (HCC), but the role of the RhoA-YAP1-autophagy pathway in HCC remains unclear. Due to the core role of liver cancer stem cells (LCSCs) in HCC metastasis and recurrence, we
Externí odkaz:
https://doaj.org/article/ba173f816531464f80ee688c7d93df36