Zobrazeno 1 - 10
of 354
pro vyhledávání: '"Shuichi KAMINOGAWA"'
Autor:
Masato Tsuda, Hiraku Okada, Natsuki Kojima, Fumiya Ishihama, Yuhei Muraki, Toshiki Oguma, Nanako Hattori, Takumi Mizoguchi, Kiyoaki Mori, Satoshi Hachimura, Yoshimasa Takahashi, Kyoko Takahashi, Shuichi Kaminogawa, Akira Hosono
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
Gut-associated lymphoid tissue (GALT), such as Peyer’s patches (PPs), are key inductive sites that generate IgA+ B cells, mainly through germinal center (GC) responses. The generation of IgA+ B cells is promoted by the presence of gut microbiota an
Externí odkaz:
https://doaj.org/article/c6303fb4b2b74513b2c0878cc2cbb81e
Autor:
Haruyo Nakajima-Adachi, Kyoko Shibahara, Yoko Fujimura, Jun Takeyama, Erika Hiraide, Akira Kikuchi, Hitoshi Murakami, Akira Hosono, Tomonori Nochi, Yoshio Wakatsuki, Naoki Shimojo, Shuichi Kaminogawa, Ryuichiro Sato, Hiroshi Kiyono, Satoshi Hachimura
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172795 (2017)
The mechanism inducing either inflammation or tolerance to orally administered food allergens remains unclear. To investigate this we analyzed mouse models of food allergy (OVA23-3) and tolerance (DO11.10 [D10]), both of which express ovalbumin (OVA)
Externí odkaz:
https://doaj.org/article/4e427ce4b9c94186ac305f008b0bbc22
Autor:
Yutaka Sugi, Kyoko Takahashi, Kenta Kurihara, Kazuaki Nakata, Hikari Narabayashi, Yuji Hamamoto, Makoto Suzuki, Masato Tsuda, Shigemasa Hanazawa, Akira Hosono, Shuichi Kaminogawa
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164858 (2016)
Immune responses against gut microbiota should be minimized to avoid unnecessary inflammation at mucosal surface. In this study, we analyzed the expression patterns of Toll-interacting protein (Tollip), an inhibitor of TLRs and IL-1 family cytokine-r
Externí odkaz:
https://doaj.org/article/447abe66a8c24cd18016c9a4d3acd7b4
Publikováno v:
Allergology International, Vol 48, Iss 1, Pp 15-23 (1999)
Food allergy, triggered by an aberrant immune response elicited by orally ingested food allergens, is generated through a complicated mechanism because the allergen interacts with the mucosal immune system (the gut- associated lymphoid tissue, GALT)
Externí odkaz:
https://doaj.org/article/76562596b3a44994bc57a1ee3684d6af
Autor:
Haruyo Nakajima-Adachi, Akira Kikuchi, Yoko Fujimura, Kyoko Shibahara, Tsuyoshi Makino, Masae Goseki-Sone, Miran Kihara-Fujioka, Tomonori Nochi, Yosuke Kurashima, Osamu Igarashi, Masafumi Yamamoto, Jun Kunisawa, Masako Toda, Shuichi Kaminogawa, Ryuichiro Sato, Hiroshi Kiyono, Satoshi Hachimura
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e107492 (2014)
BACKGROUND AND OBJECTIVE: To improve the efficacy and safety of tolerance induction for food allergies, identifying the tissues responsible for inducing intestinal inflammation and subsequent oral tolerance is important. We used OVA23-3 mice, which e
Externí odkaz:
https://doaj.org/article/ddb895cf93394b27b53dd49fd79b818b
Autor:
Gaku Harata, Fang He, Kyoko Takahashi, Akira Hosono, Kenji Miyazawa, Kazutoyo Yoda, Masaru Hiramatsu, Shuichi Kaminogawa
Publikováno v:
Microorganisms, Vol 4, Iss 4, p 40 (2016)
Mast cells play a critical role in immunoglobulin E (IgE)-mediated allergic diseases, and the degranulation of mast cells is important in the pathogenesis of these diseases. A disturbance of the intestinal microflora, especially of endogenous lactic
Externí odkaz:
https://doaj.org/article/26d854d4a30c47ebb2bb3c17551c28d7
Autor:
Tetsuro Kobayakawa, Kyoko Takahashi, Kou Nakano, Akira Hosono, Shuichi Kaminogawa, Yusuke Nakanishi, Yutaka Sugi, Masato Tsuda
Publikováno v:
ImmunoHorizons. 4(4)
A huge number of commensal bacteria inhabit the intestine, which is equipped with the largest immune system in the body. Recently, the regulation of various physiological functions of the host by these bacteria has attracted attention. In this study,
Autor:
Akira Hosono, Mana Michimori, Masato Tsuda, Masanari Noda, Kyoko Takahashi, Narumi Ishii, Haruka Arakawa, Chihiro Ubukata, Shuichi Kaminogawa
Publikováno v:
International Archives of Allergy and Immunology. 174:121-132
Background: Fructo-oligosaccharides (FOS) are prebiotic agents with immunomodulatory effects involving improvement of the intestinal microbiota and metabolome. In this study, we investigated the cellular mechanisms through which FOS modulate intestin
Autor:
Yutaka Sugi, Yusuke Nakanishi, Akira Hosono, Hikari Narabayashi, Tetsuro Kobayakawa, Shuichi Kaminogawa, Masato Tsuda, Kyoko Takahashi, Kazuaki Nakata, Shigemasa Hanazawa
Publikováno v:
The Journal of biological chemistry. 292(37)
The intestinal tract contains many commensal bacteria that modulate various physiological host functions. Dysbiosis of commensal bacteria triggers dysfunction of the intestinal epithelial barrier, leading to the induction or aggravation of intestinal
Autor:
Shuichi Kaminogawa, K. Tsubaki, Satoshi Hachimura, H. Kawakami, K. Tanabe, A. Tanioka, Akira Hosono
Publikováno v:
Scandinavian Journal of Immunology. 78:61-68
β-Glucans, glucose polymers that are the main constituents of the outer cell walls of micro-organisms such as fungi and yeast, are known to play an immunostimulatory role. We prepared β-glucan (β-(1-3),(1-6)-D-glucan) from an edible cultured fungu