Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Shuichi Horie"'
Publikováno v:
Doboku Gakkai Ronbunshuu E. 65:198-207
A walking sapace in downtown Sapporo has been rebuilt in terms of appearance on the basis of a old urban planning. Although various materials and designs were used for sidewalk pavement, complaints on slip from citizens and difficulties for maintenan
Autor:
Katsutaka Oishi, Shuichi Horie, Naoki Ohkura, Koji Shikata, Toshiki Sudo, Juzo Matsuda, Norio Ishida, Hideki Hayashi
Publikováno v:
Thrombosis Research. 123:523-527
Autor:
Taro Shiga, Shuichi Horie, Yasushi Imai, Ryozo Nagai, Norio Ishida, Ichiro Manabe, Norihiko Takeda, Katsutaka Oishi, Tomohiro Harada, Koji Maemura, Tetsuya Saito, Eisuke Amiya
Publikováno v:
Journal of Biological Chemistry. 282:32561-32567
Cardiovascular diseases are closely related to circadian rhythm, which is under the control of an internal biological clock mechanism. Although a biological clock exists not only in the hypothalamus but also in each peripheral tissue, the biological
Autor:
Manami Kasamatsu, Naoki Ohkura, Shuichi Horie, Katsutaka Oishi, Yoko Tamai, Gen-ichi Atsumi, Ayako Kurata, Juzo Matsuda, Hidenori Shirai, Norio Ishida, Nanae Fukushima, Toshiyuki Sakata, Koji Kadota
Publikováno v:
Chronobiology International. 24:651-669
This study examined circadian variation in coagulation and fibrinolytic parameters among Jcl:ICR, C3H/HeN, BALB/cA, and C57BL/6J strains of mice. Plasma plasminogen activator inhibitor 1 (PAI-1) levels fluctuated in a circadian manner and peaked in a
Autor:
Shuichi Horie, Hiroyuki Itabe, Tsutomu Hamuro, Naoki Ohkura, Sayuri Hiraishi, Tatsuya Takano, Juzo Matsuda, Yuichi Kamikubo
Publikováno v:
Antioxidants & Redox Signaling. 6:705-712
Tissue factor pathway inhibitor (TFPI) is a Kunitz-type protease inhibitor that inhibits the initial reactions of blood coagulation. In this study, we explored the nature of active components that reduce the anticoagulant activity of TFPI in oxidized
Autor:
Juzo Matsuda, Fumiko Matsumoto, Keiichiro Kizaki, Masao Kusano, Shuichi Horie, Mutsuyoshi Kazama, Hidemi Ishii
Publikováno v:
Journal of Biological Chemistry. 276:2440-2450
The interactions between retinoic acid- (RA)-dependent transcriptional regulatory sequences of the 5'-untranslated region of the thrombomodulin gene and nuclear RA-responsive proteins were studied using human pancreas BxPC-3 cells. Deletion mutants o
Publikováno v:
Thrombosis Research. 85:169-176
We examined the effects of okadaic acid, a potent specific inhibitor of protein phosphatases 1 and 2A, on the expression of thrombomodulin (TM), a cell surface anti-thrombotic glycoprotein, on cultured human umbilical endothelial cells. Okadaic acid
Autor:
Koji Oida, G. Tohda, E. Okada, Mitsuyuki Kohno, Isamu Miyamori, Jinya Suzuki, T Nakai, Hidemi Ishii, Shuichi Horie
Publikováno v:
Thrombosis and Haemostasis. 78:1228-1233
SummaryWe have investigated the effects of oxidized low density lipoproteins (oxidized LDL) on the expression of TM by THP-1 monocytic cells. TM antigen levels and its cofactor activity for thrombin-dependent protein C activation were increased by ox
Autor:
Shuichi Horie, Shinobu Noritake, Sayuri Hiraishi, Megumi Satoh, Mutsuyoshi Kazama, Hidemi Ishii, Osamu Kurusu, Keiichiro Kizaki, Tamio Nakahara, Mayumi Yamada
Publikováno v:
Biological and Pharmaceutical Bulletin. 20:625-631
The inhibitory effects of vapiprost hydrochloride (vapiprost), a novel thromboxane A2 receptor antagonist, on platelet aggregation and ATP release were studied using platelet rich plasma (PRP) of humans, guinea pigs, rabbits and rats. In in vitro exp
Publikováno v:
Journal of Biological Chemistry. 271:8458-8465
Oxidized low density lipoprotein (LDL), a potent atherogenic lipoprotein, has been shown to cause the alteration of various endothelial functions. We have examined the effect of oxidized LDL on the cofactor activity for thrombin-dependent protein C a