Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Shui On Leung"'
Publikováno v:
Journal of Immunology Research, Vol 2023 (2023)
Natural killer (NK) cell is an essential cytotoxic lymphocyte in our innate immunity. Activation of NK cells is of paramount importance in defending against pathogens, suppressing autoantibody production and regulating other immune cells. Common gamm
Externí odkaz:
https://doaj.org/article/ac0d6b34e486490481c09dc411bf32d3
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interleukins 4 (IL-4) and 21 (IL-21) belong to the common gamma chain cytokine family which are highly involved in the progression of autoimmune diseases. While IL-4 is well known to be involved in the suppression of apoptosis of autoreactive B cells
Externí odkaz:
https://doaj.org/article/cea354172d654d7aa1dc53655fd7e141
Autor:
Leilei Zhu, Rong Shi, Tongfang Zhao, Yujie Ye, Jie Tang, Yihui Hu, Peng Peng, Dong Wang, Clement Chong, Guolin Xu, Shui‐on Leung, Wei’an Yuan
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 10, Pp 1982-1996 (2023)
Abstract The purpose of this study was to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of SN1011, a novel Bruton tyrosine kinase (BTK) inhibitor, and food effects in healthy subjects. In this phase I trial, subjects re
Externí odkaz:
https://doaj.org/article/2678b20c7e79429eb9190d641800649e
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Respiratory Staphylococcus aureus infection represents a common complication in lung cancer patients, which is characterized with progressively and recurrently intratumor invasion. Although bacteriophages are widely reported as an effective
Externí odkaz:
https://doaj.org/article/c5fd495ee984430cafdff87798440ea6
C-terminal modification of a de novo designed antimicrobial peptide via capping of macrolactam rings
Autor:
Zeng, Ping, Cheng, Qipeng, Yi, Lanhua, Shui Yee Leung, Sharon, Chen, Sheng, Chan, Kin-Fai, Wong, Kwok-Yin
Publikováno v:
In Bioorganic Chemistry January 2023 130
Autor:
Jie Li, Ronald Man Yeung Wong, Yik Lok Chung, Sharon Shui Yee Leung, Simon Kwoon-Ho Chow, Margaret Ip, Wing-Hoi Cheung
Publikováno v:
Bone & Joint Research, Vol 11, Iss 2, Pp 49-60 (2022)
Aims With the ageing population, fragility fractures have become one of the most common conditions. The objective of this study was to investigate whether microbiological outcomes and fracture-healing in osteoporotic bone is worse than normal bone wi
Externí odkaz:
https://doaj.org/article/b404d5df7c494f9ab8ac8024ba619cac
Autor:
Jie Li, Sharon Shui Yee Leung, Yik Lok Chung, Simon Kwoon Ho Chow, Volker Alt, Markus Rupp, Christoph Brochhausen, Chun Sing Chui, Margaret Ip, Wing-Hoi Cheung, Ronald Man Yeung Wong
Publikováno v:
Acta Biomaterialia. 164:223-239
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c26573fb173468ba32326d209974e5db
https://doi.org/10.1016/j.actbio.2023.03.044
https://doi.org/10.1016/j.actbio.2023.03.044
Application of Pharmacokinetic-Pharmacodynamic Modeling in Drug Delivery: Development and Challenges
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
With the advancement of technology, drug delivery systems and molecules with more complex architecture are developed. As a result, the drug absorption and disposition processes after administration of these drug delivery systems and engineered molecu
Externí odkaz:
https://doaj.org/article/c8731f18d1b74c1b84808ef2525040a9
Autor:
Yannan Liu, Sharon Shui Yee Leung, Yong Huang, Yatao Guo, Ning Jiang, Puyuan Li, Jichao Chen, Rentao Wang, Changqing Bai, Zhiqiang Mi, Zhancheng Gao
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Carbapenem-resistant Klebsiella pneumoniae (CRKP) pose a significant threat to global public health. In present research, a total of 80 CRKP strains belonging to ST11 were collected with 70% (56 of 80 isolates) expressing a K47 capsular type. Thus, i
Externí odkaz:
https://doaj.org/article/bba2870669e0473694c2b294f027d9d1
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 16, Iss , Pp 316-334 (2018)
Mass spectrometry (MS) is a sensitive, specific and versatile analytical technique in the clinical laboratory that has recently undergone rapid development. From initial use in metabolic profiling, it has matured into applications including clinical
Externí odkaz:
https://doaj.org/article/b1314e3a7ac9442a8bfdc5bacec92c03