Výsledky vyhledávání - "Shuhuan Pang"

Akademický článek

TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves

Autor: Matthew Grove, Hyukmin Kim, Shuhuan Pang, Jose Paz Amaya, Guoqing Hu, Jiliang Zhou, Michel Lemay, Young-Jin Son

Publikováno v: eLife, Vol 13 (2024)

Previously we showed that the hippo pathway transcriptional effectors, YAP and TAZ, are essential for Schwann cells (SCs) to develop, maintain and regenerate myelin . Although TEAD1 has been implicated as a partner transcription factor, the mechanism

Externí odkaz: https://doaj.org/article/5348f4ba662d4a95a92f0c5764c4eca0

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Akademický článek

Influence of Laser-Based Powder Bed Fusion of Metals Process Parameters on the Formation of Defects in Al-Zn-Mg-Cu Alloy Using Path Analysis

Autor: Biao Huang, Hongqun Tang, Jincheng Huang, Yuanxiang Jia, Liuhui Liao, Shuhuan Pang, Xu Zheng, Zhendong Chen

Publikováno v: Micromachines, Vol 15, Iss 9, p 1121 (2024)

High-strength aluminium alloys are prone to porosity and cracking during laser-based powder bed fusion of metals (PBF-LB/M) due to the complex solidification behaviour, thus limiting the preparation of high-quality aluminium alloys. In order to effec

Externí odkaz: https://doaj.org/article/cce3e5a19ea14562b7be0beaa3b4aef9

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Akademický článek

Co-targeting B-RAF and PTEN Enables Sensory Axons to Regenerate Across and Beyond the Spinal Cord Injury

Autor: Harun N. Noristani, Hyukmin Kim, Shuhuan Pang, Jian Zhong, Young-Jin Son

Publikováno v: Frontiers in Molecular Neuroscience, Vol 15 (2022)

Primary sensory axons in adult mammals fail to regenerate after spinal cord injury (SCI), in part due to insufficient intrinsic growth potential. Robustly boosting their growth potential continues to be a challenge. Previously, we showed that constit

Externí odkaz: https://doaj.org/article/b098ec788d1f4975a2e8d24517053aa0

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Akademický článek

Co-targeting myelin inhibitors and CSPGs markedly enhances regeneration of GDNF-stimulated, but not conditioning-lesioned, sensory axons into the spinal cord

Autor: Jinbin Zhai, Hyukmin Kim, Seung Baek Han, Meredith Manire, Rachel Yoo, Shuhuan Pang, George M Smith, Young-Jin Son

Publikováno v: eLife, Vol 10 (2021)

A major barrier to intraspinal regeneration after dorsal root (DR) injury is the DR entry zone (DREZ), the CNS/PNS interface. DR axons stop regenerating at the DREZ, even if regenerative capacity is increased by a nerve conditioning lesion. This pote

Externí odkaz: https://doaj.org/article/801649fb2cb447c1b57b2b765a724588

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Supplementary Figure 1 from MELK and EZH2 Cooperate to Regulate Medulloblastoma Cancer Stem-like Cell Proliferation and Differentiation

Autor: Chunyu Gu, Chunjiang Yu, Hongwei Zhang, Mingshan Zhang, Haoran Wang, Xueling Qi, Shuhuan Pang, Hongyu Yuan, Junping Zhang, Youliang Sun, Qianwen Sun, Hailong Liu

A-B, Expression of MELK and EZH2 in pan-cancers from TCGA database. C, Correlation between MELK and EZH2 in SHH associated MB from GSE50765 dataset. D, Correlation between MELK and EZH2 mRNA relative expression in GBM from TCGA database.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc0db0062cc93ac30203925505dd97d
https://doi.org/10.1158/1541-7786.22514767.v1

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Supplementary Figure 5 from MELK and EZH2 Cooperate to Regulate Medulloblastoma Cancer Stem-like Cell Proliferation and Differentiation

Autor: Chunyu Gu, Chunjiang Yu, Hongwei Zhang, Mingshan Zhang, Haoran Wang, Xueling Qi, Shuhuan Pang, Hongyu Yuan, Junping Zhang, Youliang Sun, Qianwen Sun, Hailong Liu

Daoy CSCs were treated with the indicated concentration of OTSSP167, DZNep and combination of both inhibitors for 42 h and proliferation was measured by MTT. No significant differences existed in the three therapeutic groups (p = 0.31).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407ad5e3ff3e878a6f8158bea31b6430
https://doi.org/10.1158/1541-7786.22514755

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