Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Shuhong Shen"'
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-16 (2024)
Abstract Background Macrophage-based cell therapy is promising in solid tumors, but the efficient acquisition of macrophages remains a challenge. Induced pluripotent stem cell (iPSC)-induced macrophages are a valuable source, but time-consuming and c
Externí odkaz:
https://doaj.org/article/e05057bb1ab942e9a5e47cdaf0ba93d5
Autor:
Chi Zhang, Kathy Yuen Yee Chan, Wing Hei Ng, John Tak Kit Cheung, Qiwei Sun, Han Wang, Po Yee Chung, Frankie Wai Tsoi Cheng, Alex Wing Kwan Leung, Xiao-Bing Zhang, Po Yi Lee, Siu Ping Fok, Guanglan Lin, Ellen Ngar Yun Poon, Jian-Hua Feng, Yan-Lai Tang, Xue-Qun Luo, Li-Bin Huang, Wei Kang, Patrick Ming Kuen Tang, Junbin Huang, Chun Chen, Junchao Dong, Ester Mejstrikova, Jiaoyang Cai, Yu Liu, Shuhong Shen, Jun J Yang, Patrick Man Pan Yuen, Chi Kong Li, Kam Tong Leung
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Resistance to glucocorticoids (GCs), the common agents for remission induction in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL), poses a significant therapeutic hurdle. Therefore, dissecting the mechanisms shaping GC resistance co
Externí odkaz:
https://doaj.org/article/b91b2983d67042199d70adb7860fbe66
Autor:
Han Wang, Huiying Sun, Bilin Liang, Fang Zhang, Fan Yang, Bowen Cui, Lixia Ding, Xiang Wang, Ronghua Wang, Jiaoyang Cai, Yanjing Tang, Jianan Rao, Wenting Hu, Shuang Zhao, Wenyan Wu, Xiaoxiao Chen, Kefei Wu, Junchen Lai, Yangyang Xie, Benshang Li, Jingyan Tang, Shuhong Shen, Yu Liu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract For around half of the pediatric B-lineage acute lymphoblastic leukemia (B-ALL) patients, the molecular mechanism of relapse remains unclear. To fill this gap in knowledge, here we characterize the chromatin accessibility landscape in pediat
Externí odkaz:
https://doaj.org/article/fe96c0b766af471fa983e4b57c10585c
Autor:
Tianyou Wang, Xiaofan Zhu, Yumei Chen, Shuhong Shen, Yongmin Tang, Jingying Zhang, Yingyi He, Hui Zhang, Ju Gao, Jianpei Fang, Rong Liu, Xiaoyan Wu, Jinchuan Sun, Minlu Zhang
Publikováno v:
Drugs in R&D, Vol 23, Iss 2, Pp 129-140 (2023)
Abstract Introduction Despite rasburicase's proven efficiency in Caucasians, Japanese, and Koreans, studies evaluating the safety and effectiveness of rasburicase in Chinese pediatric patients with non-Hodgkin’s lymphoma (NHL) and acute leukemia (A
Externí odkaz:
https://doaj.org/article/ac04eccf4d1f497e8458b936e1df7fc3
Autor:
Wenting Hu, Yin Ting Cheung, Yanjing Tang, Li Hong, Yuan Zhu, Jing Chen, Zhuo Wang, Min Zhou, Yijin Gao, Benshang Li, Huiliang Xue, Longjun Gu, Shuhong Shen, Jingyan Tang, Ching‐Hon Pui, Hiroto Inaba, Jiaoyang Cai
Publikováno v:
Cancer Medicine, Vol 12, Iss 3, Pp 2850-2860 (2023)
Abstract Purpose Studies of the association between body mass index (BMI) at diagnosis and treatment outcome in children with acute lymphoblastic leukemia (ALL) have yielded inconsistent results. Hence, we conducted a retrospective study in a large c
Externí odkaz:
https://doaj.org/article/c3221e1a71b2482881c4f47697624d97
Autor:
Ting Liu, Jianan Rao, Wenting Hu, Bowen Cui, Jiaoyang Cai, Yuhan Liu, Huiying Sun, Xiaoxiao Chen, Yanjing Tang, Jing Chen, Xiang Wang, Han Wang, Wubin Qian, Binchen Mao, Sheng Guo, Ronghua Wang, Yu Liu, Shuhong Shen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The genomic landscape of pediatric acute myeloid leukemia (AML) has mostly been characterised for Western populations. Here, the authors identify potential driver alterations in Chinese pediatric AML, which differ from Western populations, and propos
Externí odkaz:
https://doaj.org/article/db80351d3f8146a4b5fed2c7d1382f15
Autor:
Peifang Xiao, Jiaoyang Cai, Ju Gao, Wei Gao, Xianmin Guan, Alex Wing Kwan Leung, Yiying He, Yong Zhuang, Jinhua Chu, Xiaowen Zhai, Benquan Qi, Aiguo Liu, Liangchun Yang, Jiashi Zhu, Zheng Li, Xin Tian, Yao Xue, Li Hao, Xuedong Wu, Fen Zhou, Lingzhen Wang, Jingyan Tang, Shuhong Shen, Shaoyan Hu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Background and methodsThe study evaluated prognostic factors associated with varicella-zoster virus (VZV) infection and mortality in children with acute lymphoblastic leukemia (ALL) using data from the multicenter Chinese Children’s Cancer Group AL
Externí odkaz:
https://doaj.org/article/640448863f93459f87525253ca7765bc
Autor:
Yi-Fan Zhang, Xiao-Lin Wang, Chun-Hui Xu, Na Liu, Ling Zhang, Yu-Ming Zhang, Yin-Yin Xie, Yuan-Liang Zhang, Qiu-Hua Huang, Lan Wang, Zhu Chen, Sai-Juan Chen, Robert G. Roeder, Shuhong Shen, Kai Xue, Xiao-Jian Sun
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The ETO-family transcriptional corepressors, including ETO, ETO2, and MTGR1, are all involved in leukemia-causing chromosomal translocations. In every case, an ETO-family corepressor acquires a DNA-binding domain (DBD) to form a typical transcription
Externí odkaz:
https://doaj.org/article/8a602dc4f5f34b6aa8aa68c6b8b9d60a
Autor:
Zhengyu Wu, Fang Zhang, Chengzhu Liu, Shuhong Shen, Jinhua Chu, Linhai Yang, Zhiwei Xie, Yu Liu, Kangkang Liu, Ningling Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Previous studies have shown that, the clinical features and prognosis of ZNF384-rearranged pediatric acute lymphoblastic leukemia (ALL) depend on its translocation partners. We report two cases of TCF4-ZNF384 fusion, one 6-year-old girl and one 10-ye
Externí odkaz:
https://doaj.org/article/e38ced66d0f74fb898ca44236fb0c1f7
Autor:
Yong Zhuang, Kefei Wu, Xiaofan Zhu, Jiaoyang Cai, Shaoyan Hu, Ju Gao, Hua Jiang, Xiaowen Zhai, Xin Tian, Yongjun Fang, Runming Jin, Qun Hu, Hui Jiang, Ningling Wang, Lirong Sun, Wing Kwan Leung, Minghua Yang, Kaili Pan, Xuedong Wu, Changda Liang, Shuhong Shen, Jie Yu, Xiuli Ju
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
It is urgently necessary to reduce the adverse effects of chemotherapy while maintaining their cure high rates for children with acute lymphoblastic leukemia (ALL). The present study aimed to determine whether the dose intensity of daunorubicin durin
Externí odkaz:
https://doaj.org/article/7f55fedb21a44e62a1b5db204d7d4239