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pro vyhledávání: '"Shuhei Shiroto"'
Publikováno v:
Chemistry Letters. 50:1806-1809
Here we demonstrate that a guanine-to-adenine substitution within guanine repeat sequences in the MSH 5′-UTR weakens G-quadruplex stability, leading to increased protein synthesis. The abnormal pro...
Autor:
Yousuke Katsuda, Shin-ichi Sato, Maimi Inoue, Hisashi Tsugawa, Takuto Kamura, Tomoki Kida, Rio Matsumoto, Sefan Asamitsu, Norifumi Shioda, Shuhei Shiroto, Yoshiki Oosawatsu, Kenji Yatsuzuka, Yusuke Kitamura, Masaki Hagihara, Toshihiro Ihara, Motonari Uesugi
Publikováno v:
Nucleic acids research. 50(14)
Tandem repeats of guanine-rich sequences in RNA often form thermodynamically stable four-stranded RNA structures. Such RNA G-quadruplexes have long been considered to be linked to essential biological processes, yet their physiological significance i