Výsledky vyhledávání - "Shuhei Kishikawa"

Supplementary Tables from Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma

Autor: Yasuyuki Kaneta, Takahiko Seki, Osamu Ubukata, Yumi Matsui, Shuhei Kishikawa, Takashi Shimada, Toshiki Tabata, Sho Takechi, Kosuke Takeuchi, Takeshi Shida, Yoshihiro Shibata, Ryo Murakami, Mana Hatanaka, Yoichi Munehira, Kohei Takano

Supplementary Tables from Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63db35c90bd3fa1e8ea96916e9e0705f
https://doi.org/10.1158/1535-7163.22523761.v1

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Supplementary Figures from Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma

Supplementary Figures from Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22757ff9c78ad64b565af1b3c30e1dd4
https://doi.org/10.1158/1535-7163.22523767

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Supplementary Methods from Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma

Supplementary Methods from Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2c64c2d11235ff09916379c8ca2dd8
https://doi.org/10.1158/1535-7163.22523764.v1

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Discovery of a novel ATP-competitive MEK inhibitor DS03090629 that overcomes resistance conferred by BRAF overexpression in BRAF-mutated melanoma

Autor: Kohei Takano, Yoichi Munehira, Mana Hatanaka, Ryo Murakami, Yoshihiro Shibata, Takeshi Shida, Kosuke Takeuchi, Sho Takechi, Toshiki Tabata, Takashi Shimada, Shuhei Kishikawa, Yumi Matsui, Osamu Ubukata, Takahiko Seki, Yasuyuki Kaneta

Publikováno v: Molecular cancer therapeutics.

Patients with melanoma with activating BRAF mutations (BRAF V600E/K) initially respond to combination therapy of BRAF and MEK inhibitors. However, their clinical efficacy is limited by acquired resistance, in some cases driven by amplification of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6040d68a8b817ab0dfc5fb7e8344a54
https://pubmed.ncbi.nlm.nih.gov/36622773

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Analysis of binding residues in monoclonal antibody with high affinity for the head domain of the rat P2X4 receptor

Autor: Tadashi Ueda, Kazuhide Inoue, Yoshito Abe, Tatsuhiro Igawa, Makoto Tsuda, Shuhei Kishikawa

Publikováno v: The Journal of Biochemistry. 169:491-496

P2X4 receptor is known to be involved in neuropathic pain. In order to detect the expression of P2X4 receptor on microglia at the time of onset of neuropathic pain, one approach consists on the preparation of the monoclonal antibodies with both selec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4abc92df50afebee7ec0fbb37be3aff
https://doi.org/10.1093/jb/mvaa124

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Evidence for detection of rat P2X4 receptor expressed on cells by generating monoclonal antibodies recognizing the native structure

Autor: Hidetoshi Tozaki-Saitoh, Tomohiro Yamashita, Saki Nagai, Chinatsu Shinozaki, Shuhei Kishikawa, Tadashi Ueda, Mitsunori Shiroishi, Hiroyuki Tanaka, Makoto Tsuda, Tatsuhiro Igawa, Kazuhide Inoue, Yoshito Abe

Publikováno v: Purinergic Signalling. 15:27-35

P2X purinergic receptors are ATP-driven ionic channels expressed as trimers and showing various functions. A subtype, the P2X4 receptor present on microglial cells is highly involved in neuropathic pain. In this study, in order to prepare antibodies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d92e8d5cf3b32160e058de89e67e26e
https://doi.org/10.1007/s11302-019-09646-5

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Akademický článek

Analysis of binding residues in monoclonal antibody with high affinity for the head domain of the rat P2X4 receptor.

Autor: Igawa, Tatsuhiro¹ (AUTHOR), Kishikawa, Shuhei¹ (AUTHOR), Abe, Yoshito^1,2 (AUTHOR), Tsuda, Makoto³ (AUTHOR), Inoue, Kazuhide⁴ (AUTHOR), Ueda, Tadashi¹ (AUTHOR) ueda@phar.kyushu-u.ac.jp

Publikováno v: Journal of Biochemistry. Apr2021, Vol. 169 Issue 4, p491-496. 6p.

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Akademický článek

Evidence for detection of rat P2X4 receptor expressed on cells by generating monoclonal antibodies recognizing the native structure.

Autor: Igawa, Tatsuhiro, Kishikawa, Shuhei, Abe, Yoshito, Yamashita, Tomohiro, Nagai, Saki, Shiroishi, Mitsunori, Shinozaki, Chinatsu, Tanaka, Hiroyuki, Tozaki-Saitoh, Hidetoshi, Tsuda, Makoto, Inoue, Kazuhide, Ueda, Tadashi

Publikováno v: Purinergic Signalling; Mar2019, Vol. 15 Issue 1, p27-35, 9p

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