Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Shuhei Ishikura"'
Autor:
Masahiro Ogawa, Tadashi Okamura, Shuhei Ishikura, Keiko Doi, Hiroshi Matsuzaki, Yoko Tanaka, Takeharu Ota, Kunihiro Hayakawa, Harumi Suzuki, Toshiyuki Tsunoda, Takehiko Sasazuki, Senji Shirasawa
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76254 (2013)
The human ZFAT gene was originally identified as a susceptibility gene for autoimmune thyroid disease. Mouse Zfat is a critical transcriptional regulator for primitive hematopoiesis and required for peripheral T cell homeostasis. However, its physiol
Externí odkaz:
https://doaj.org/article/1a91b41879c94f25b102ebd5f8a6d1d3
Autor:
KAZUMASA YOSHIDA, KENSUKE NISHI, SHUHEI ISHIKURA, KAZUHIKO NAKABAYASHI, RYO YAZAKI, TAKASHI OHSHIMA, MASAHIKO SUENAGA, SENJI SHIRASAWA, TOSHIYUKI TSUNODA
Publikováno v:
Anticancer Research. 42:3993-4001
In a screen of compounds to selectively suppress the growth of cancer spheroids, which contained mutant (mt) KRAS, NPD10621 was discovered and associated derivatives were investigated.Spheroid areas from HCT116-derived HKe3 spheroids expressing wild
Publikováno v:
Nucleic Acids Research
Centromeres are genomic regions essential for faithful chromosome segregation. Transcription of noncoding RNA (ncRNA) at centromeres is important for their formation and functions. Here, we report the molecular mechanism by which the transcriptional
Publikováno v:
Journal of Biological Chemistry. 298:102528
The centromere is an essential chromosomal structure for faithful chromosome segregation during cell division. No protein-coding genes exist at the centromeres, but centromeric DNA is actively transcribed into noncoding RNA (ncRNA). This centromeric
Autor:
Senji Shirasawa, Ryo Yazaki, Masayoshi Nagai, Sayuri Hashimoto, Kensuke Nishi, Takashi Ohshima, Shuhei Ishikura, Kazuhiko Nakabayashi, Toshiyuki Tsunoda, Masahiko Suenaga
Publikováno v:
Anticancer research. 41(8)
Background/aim Among compounds from natural products selectively suppressing the growth of cancer spheroids, which have mutant (mt) KRAS, NP910 was selected and its derivatives explored. Materials and methods The area of HKe3 spheroids expressing wil
Autor:
Shiori Yamano, Shuhei Ishikura, Toshiyuki Tsunoda, Senji Shirasawa, Midori Koyanagi, Aya Fujikane, Kensuke Nishi, Keiko Doi, Yoko Tanaka
Publikováno v:
Anticancer Research. 39:4495-4502
Background/aim In mice, fetal liver is the first tissue of definitive erythropoiesis for definitive erythroid expansion and maturation. ZFAT, originally identified as a candidate susceptibility gene for autoimmune thyroid disease, has been reported t
Autor:
Toshiyuki Tsunoda, Masayoshi Nagai, Kensuke Nishi, Midori Koyanagi, Senji Shirasawa, Shuhei Ishikura, Yoko Tanaka
Publikováno v:
Journal of Cellular Biochemistry
Adipocytes play crucial roles in the control of whole‐body energy homeostasis. Differentiation and functions of the adipocytes are regulated by various transcription factors. Zfat (zinc‐finger protein with AT‐hook) is a transcriptional regulato
Autor:
Kensuke, Nishi, Shuhei, Ishikura, Masayo, Umebayashi, Takashi, Morisaki, Takashi, Inozume, Tetsushi, Kinugasa, Mikiko, Aoki, Satoshi, Nimura, Anthony, Swain, Yoichiro, Yoshida, Suguru, Hasegawa, Kazuki, Nabeshima, Toshifumi, Sakata, Senji, Shirasawa, Toshiyuki, Tsunoda
Publikováno v:
Anticancer research. 40(8)
Roles for mutant (mt) KRAS in the innate immune microenvironment in colorectal cancer (CRC) were explored.Human CRC HCT116-derived, mtKRAS-disrupted (HKe3) cells that express exogenous mtKRAS and allogenic cytokine-activated killer (CAK) cells were c
Autor:
Hao Luo, Ryo Yazaki, Takashi Ohshima, Shuhei Ishikura, Senji Shirasawa, Kensuke Nishi, Naoyuki Morishige, Toshiyuki Tsunoda, Anthony Swain
Publikováno v:
Anticancer Research. 38:4247-4256
Background/aim During screening for compounds that selectively suppress growth of human colorectal cancer (CRC) spheroids with mutant (mt) KRAS, the uridine analogue, 5-bromouridine (BrUrd) was identified and its derivatives were explored. Materials
Autor:
Shuhei Ishikura, Kazumasa Yoshida, Kazuhiko Nakabayashi, Toshiyuki Tsunoda, Senji Shirasawa, Sayuri Hashimoto
Publikováno v:
The Journal of Biological Chemistry
The centromere is a chromosomal locus that is essential for the accurate segregation of chromosomes during cell division. Transcription of noncoding RNA (ncRNA) at the centromere plays a crucial role in centromere function. The zinc-finger transcript