Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shuhei Chijiwa"'
Publikováno v:
The Journal of Antibiotics. 60:640-644
In the course of our screening program for regulators of the expression of GRP78 molecular chaperone, JBIR-04 (1) and -05 (2) were isolated from Streptomyces violaceoniger 4541-SVS3 as congeners of prunustatin A (3). The structures of 1 and 2 were de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54d7557254cf1e684a024806900c816
https://doi.org/10.1038/ja.2007.82
https://doi.org/10.1038/ja.2007.82
Publikováno v:
Organic Letters. 9:1457-1460
[structure: see text] Versipelostatin is the first compound which specifically inhibits the expression of GRP78 and the resultant robust cell death under stress conditions, in contrast to the weak cytotoxicity under normal conditions. Versipelostatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d141e9fd35829cbd651953425ed8a2a6
https://doi.org/10.1021/ol070042t
https://doi.org/10.1021/ol070042t
Autor:
Yukiko Umeda, Kazuo Furihata, Kazuo Shin-ya, Keiko Furihata, Yoichi Hayakawa, Shuhei Chijiwa, Haruo Seto
Publikováno v:
Tetrahedron Letters. 46:1273-1276
Inhibition of the mevalonate pathway by an HMG-CoA reductase inhibitor, mevalotin, in Streptomyces prunicolor possessing both mevalonate and MEP pathways resulted in the production of a new metabolite mevashuntin that consisted of conjugated thiazolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf5e89b6fd26d7d50c5855340dfe1e4
https://doi.org/10.1016/j.tetlet.2004.12.134
https://doi.org/10.1016/j.tetlet.2004.12.134
Autor:
Kazuo Furihata, Kazuo Shin-ya, Toyoshige Endo, Tomohisa Kuzuyama, Masahiro Ogata, Shuhei Chijiwa, Yoichi Hayakawa, Hae Ryong Park
Publikováno v:
Tetrahedron Letters. 44:5897-5900
Versipelostatin, a novel microbial metabolite consisting of a 17-membered macrocyclic aglycone with an α-acyltetronic acid functional group and sugar moieties was shown to be biosynthesized through a polyketide intermediate and the involvement of gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7bc6cf8b830192171ac95169d72fb9
https://doi.org/10.1016/s0040-4039(03)01389-3
https://doi.org/10.1016/s0040-4039(03)01389-3
Publikováno v:
ChemInform. 40
A Novel Versipelostatin Analogue, Versipelostatin F Isolated from Streptomyces versipellis 4083-SVS6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bcdfa5293acd4927f9ed804c96e2018
https://doi.org/10.1002/chin.200929204
https://doi.org/10.1002/chin.200929204
Autor:
Atsushi Yoshizawa, Motoki Takagi, Hiroshi Tanaka, Jun-ya Ueda, Kazuo Shin-ya, Shuhei Chijiwa, Takashi Takahashi
Publikováno v:
Chemistry, an Asian journal. 4(7)
Efficient synthesis of the deoxysugar part of versipelostatin (VST) was achieved by direct and stereoselective glycosylation of the reduced VST aglycon. Activation of 2-deoxyglycosyl imidate with IBr under basic conditions enables alpha-selective gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e48fdd18a061d49395e8a0bd938d93
https://pubmed.ncbi.nlm.nih.gov/19347890
https://pubmed.ncbi.nlm.nih.gov/19347890
A novel versipelostatin analogue, versipelostatin F isolated from Streptomyces versipellis 4083-SVS6
Publikováno v:
The Journal of antibiotics. 61(12)
A novel versipelostatin (1) analogue, versipelostatin F (2) was isolated from Streptomyces versipellis 4083-SVS6. The structure of 2 was determined by the analyses of the spectroscopic data. Compound 2 inhibited the expression of GRP78 induced by 2-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b07e4d4955274b393e656ed043902f
https://pubmed.ncbi.nlm.nih.gov/19194034
https://pubmed.ncbi.nlm.nih.gov/19194034
Publikováno v:
ChemInform. 39
A novel compound of antimycin family, JBIR-06 (1), was isolated from Streptomyces sp. ML55. The structure of 1 was established as a twelve-membered macrocyclic skeleton with a 3-(formylamino)-2-hydroxybenzamide based on the spectroscopic data. Compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c895444ac33a0bc63832e107e48b5ffb
https://doi.org/10.1002/chin.200843204
https://doi.org/10.1002/chin.200843204
Publikováno v:
The Journal of antibiotics. 61(4)
A novel compound of antimycin family, JBIR-06 (1), was isolated from Streptomyces sp. ML55. The structure of 1 was established as a twelve-membered macrocyclic skeleton with a 3-(formylamino)-2-hydroxybenzamide based on the spectroscopic data. Compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca3b5d0a6ee8d75f6808fb1e5ee359a
https://pubmed.ncbi.nlm.nih.gov/18503204
https://pubmed.ncbi.nlm.nih.gov/18503204
Publikováno v:
ChemInform. 39
In the course of our screening program for regulators of the expression of GRP78 molecular chaperone, JBIR-04 (1) and -05 (2) were isolated from Streptomyces violaceoniger 4541-SVS3 as congeners of prunustatin A (3). The structures of 1 and 2 were de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31b3d5e6cd9f572cc06f60229c083495
https://doi.org/10.1002/chin.200814226
https://doi.org/10.1002/chin.200814226