Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Shugang Qin"'
Autor:
Yupei Zhang, Songhui Zhai, Hai Huang, Shugang Qin, Min Sun, Yuting Chen, Xing Lan, Guohong Li, Zhiying Huang, Denggang Wang, Yaoyao Luo, Wen Xiao, Hao Li, Xi He, Meiwan Chen, Xingchen Peng, Xiangrong Song
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract The signal sequence played a crucial role in the efficacy of mRNA vaccines against virus pandemic by influencing antigen translation. However, limited research had been conducted to compare and analyze the specific mechanisms involved. In th
Externí odkaz:
https://doaj.org/article/8320420af43a40c6a212131d7d5098fe
Autor:
Xiaoshan Tang, Miaozhe Huo, Yuting Chen, Hai Huang, Shugang Qin, Jiaqi Luo, Zeyi Qin, Xin Jiang, Yongmei Liu, Xing Duan, Ruohan Wang, Lingxi Chen, Hao Li, Na Fan, Zhongshan He, Xi He, Bairong Shen, Shuai Cheng Li, Xiangrong Song
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1814-1826 (2024)
Efficient translation mediated by the 5′ untranslated region (5′ UTR) is essential for the robust efficacy of mRNA vaccines. However, the N1-methyl-pseudouridine (m1Ψ) modification of mRNA can impact the translation efficiency of the 5′ UTR. W
Externí odkaz:
https://doaj.org/article/86ce24bef18c4089ae453704e1c42e55
Autor:
Xing Lan, Shugang Qin, Huan Liu, Mengran Guo, Yupei Zhang, Xinyang Jin, Xing Duan, Min Sun, Zhenjun Liu, Wenyan Wang, Qian Zheng, Xuelian Liao, Jinpeng Chen, Yan Kang, Yongmei Xie, Xiangrong Song
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Multidrug-resistant (MDR) Acinetobacter baumannii (A. baumannii) is a formidable pathogen responsible for severe intracranial infections post-craniotomy, exhibiting a mortality rate as high as 71%. Tigecycline (TGC), a broad-spectrum antibio
Externí odkaz:
https://doaj.org/article/0d9c988c5b3c425da0bc59d4aca7286b
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/ed19ad2e550d492e94168e73aaef22b5
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/70101e1fe5cf4b548b52aa48dee8dfff
Autor:
Shugang Qin, Hai Huang, Wen Xiao, Kepan Chen, Xi He, Xiaoshan Tang, Zhiying Huang, Yupei Zhang, Xing Duan, Na Fan, Qian Zheng, Min Wu, Guangwen Lu, Yuquan Wei, Xiawei Wei, Xiangrong Song
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 10, Pp 4291-4304 (2023)
There are currently approximately 4000 mutations in the SARS-CoV-2 S protein gene and emerging SARS-CoV-2 variants continue to spread rapidly worldwide. Universal vaccines with high efficacy and safety urgently need to be developed to prevent SARS-Co
Externí odkaz:
https://doaj.org/article/331d1eae8f9649408883e36a177e91ee
Autor:
Xing Duan, Yi Zhang, Mengran Guo, Na Fan, Kepan Chen, Shugang Qin, Wen Xiao, Qian Zheng, Hai Huang, Xiawei Wei, Yuquan Wei, Xiangrong Song
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 942-954 (2023)
The extraordinary advantages associated with mRNA vaccines, including their high efficiency, relatively low severity of side effects, and ease of manufacture, have enabled them to be a promising immunotherapy approach against various infectious disea
Externí odkaz:
https://doaj.org/article/cf266b92749845f2895c25a70a58ba16
Autor:
Shugang Qin, Wen Xiao, Chuanmin Zhou, Qinqin Pu, Xin Deng, Lefu Lan, Haihua Liang, Xiangrong Song, Min Wu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-27 (2022)
Abstract Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive pulmonary disorder (COPD), cancer, and severe infection requiring
Externí odkaz:
https://doaj.org/article/4182bfefaa424d4ea830077145317bea
Autor:
Shugang Qin, Xiaoshan Tang, Yuting Chen, Kepan Chen, Na Fan, Wen Xiao, Qian Zheng, Guohong Li, Yuqing Teng, Min Wu, Xiangrong Song
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-35 (2022)
Abstract The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide range of incurable diseases. Recent rapid advances in biotechnology and molecular medicine have enabled the production of almost any functional protein/peptid
Externí odkaz:
https://doaj.org/article/aa85f05613f440eda14812445c77b468
Autor:
Mengran Guo, Shugang Qin, Shiyan Wang, Min Sun, Huiling Yang, Xinchun Wang, Ping Fan, Zhaohui Jin
Publikováno v:
Molecules, Vol 28, Iss 17, p 6370 (2023)
Herbal medicines have gained recognition among physicians and patients due to their lower adverse effects compared to modern medicines. They are extensively used to treat various diseases, including cancer, cardiovascular issues, chronic inflammation
Externí odkaz:
https://doaj.org/article/f2de74254a6c412d928aaa4d578a8cf6