Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shugang, Xing"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Most cases of acute leukemia (AL) with KMT2A rearrangement (KMT2A-r) have a dismal prognosis. Detection of this aberration in Chinese adult patients relies on reverse transcription polymerase chain reaction (RT-PCR) and chromosome banding an
Externí odkaz:
https://doaj.org/article/68d05486d74c4b11b232c79e9ad9b7fe
Autor:
Kefeng Shen, Meilan Zhang, Jiachen Wang, Wei Mu, Jin Wang, Chunyan Wang, Shugang Xing, Zhenya Hong, Min Xiao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Fanconi anemia (FA) genes play critical roles in the repair of DNA lesions. Non-FA (or underlying FA) patients harboring heterozygous germline FA gene mutations may also face an increased risk of developing bone marrow failure, primary immunodeficien
Externí odkaz:
https://doaj.org/article/9da416af588446f08a971c31604aa349
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Objectives Survivors of diffuse large B-cell lymphoma (DLBCL) are at an increased risk of developing second primary malignancies. However, the risk of secondary acute myeloid leukaemia (sAML) has not been previously described in detail, and the outco
Externí odkaz:
https://doaj.org/article/9745c25c0d204d17a4bd4d46e54fe631
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Immunoglobulin heavy chain translocations (IGH-t) have occasionally been reported in Chinese patients with chronic lymphocytic leukemia (CLL). The objective of the present study was to identify the clinicopathologic features of patients with IGH-t CL
Externí odkaz:
https://doaj.org/article/46fa831e4ba944dc8e90f38590713386
Autor:
Jiachen Wang, Kefeng Shen, Wei Mu, Weigang Li, Meilan Zhang, Wei Zhang, Zhe Li, Tong Ge, Zhoujie Zhu, Shangkun Zhang, Caixia Chen, Shugang Xing, Li Zhu, Liting Chen, Na Wang, Liang Huang, Dengju Li, Min Xiao, Jianfeng Zhou
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite impressive progress, a significant portion of patients still experience primary or secondary resistance to chimeric antigen receptor (CAR) T-cell immunotherapy for relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL). The mechanism o
Externí odkaz:
https://doaj.org/article/9c9998cc465044e09192ee9afcaca0c9
Autor:
Wei Mu, Xiaolu Long, Haodong Cai, Caixia Chen, Guang Hu, Yaoyao Lou, Shugang Xing, Di Wang, Jue Wang, Min Xiao, Kun Wang, Zhongyi Sun, Chunrui Li, Jianfeng Zhou, Liting Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Different from canonical drugs, CAR T-cells are “living drugs”, which derived from patient’s own blood. Studies of the pharmacokinetics of CAR T-cells could improve our understanding of their efficacy, safety, optimal dosage, and other characte
Externí odkaz:
https://doaj.org/article/74c0e198ea20496a9dc83f5be0223190
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BackgroundA translocation t(14;19)(q32;q13) leading to a fusion of IGH and BCL3 which is a rare cytogenetic abnormality in CLL patients, has a more aggressive clinical course with a shorter time to first treatment (TTT) and worse overall survival (OS
Externí odkaz:
https://doaj.org/article/298f79b3cd54426ea55b003332494cf5
Publikováno v:
In Translational Oncology February 2016 9(1):1-7
Publikováno v:
International Journal of Colorectal Disease. 38
Publikováno v:
BMJ open. 12(9)
ObjectivesSurvivors of diffuse large B-cell lymphoma (DLBCL) are at an increased risk of developing second primary malignancies. However, the risk of secondary acute myeloid leukaemia (sAML) has not been previously described in detail, and the outcom