Výsledky vyhledávání - "Shuchi, Nagar"

Akademický článek

Exploration of Phytoconstituents From and as Potential Therapeutics Against SARS-CoV-2 RdRp

Autor: Khushboo Pandey, Kiran Bharat Lokhande, K Venkateswara Swamy, Shuchi Nagar, Manjusha Dake

Publikováno v: Bioinformatics and Biology Insights, Vol 15 (2021)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide has increased the importance of computational tools to design a drug or vaccine in reduced time with minimum risk. Earlier studies have emphasized the important role of RNA-depend

Externí odkaz: https://doaj.org/article/f929c830511f4536b8d41428b4f49982

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Dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) by resveratrol derivatives in cancer therapy: in silico approach

Autor: Sayali Doiphode, Kiran Bharat Lokhande, Payel Ghosh, K. V. Swamy, Shuchi Nagar

Publikováno v: Journal of Biomolecular Structure and Dynamics. :1-16

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c5edcf5cd6a2c54f0f2134edc403c17
https://doi.org/10.1080/07391102.2022.2135599

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Flavonoids: Recent Advances and Applications in Crop Breeding

Autor: Shuchi, Nagar, Saurabh, Dey, Aishik, Das, Soumya, Basu

Publikováno v: Flavonoid Metabolism-Recent Advances and Applications in Crop Breeding ISBN: 9781803567044
Flavonoid Metabolism-Recent Advances and Applications in Crop Breeding

Flavonoids are secondary metabolites that perform a wide range of roles in plants. These include their involvement in plant growth, pigmentation, and UV protection, to a variety of defense and signaling activities. Flavonoids such as chalcones, flavo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21ddc026606256c4f8f64544124ad1f
https://doi.org/10.5772/intechopen.107565

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Novel B, C-ring truncated deguelin derivatives reveals as potential inhibitors of cyclin D1 and cyclin E using molecular docking and molecular dynamic simulation

Autor: K. Venkateswara Swamy, Kiran Bharat Lokhande, Shuchi Nagar, Payel Ghosh

Publikováno v: Molecular Diversity. 26:2295-2309

The overexpression of cyclin D1 and cyclin E due to their oncogenic potential and amplification has been associated with a higher mortality rate in many cancers. The deguelin is a natural compound, has shown promising anti-cancer activity by directly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34428b996970f01991f2fdd3421cfa9c
https://doi.org/10.1007/s11030-021-10334-z

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Pharmacoinformatics-based identification of transmembrane protease serine-2 inhibitors from Morus Alba as SARS-CoV-2 cell entry inhibitors

Autor: Siham A. Alissa, Hassna Mohammed Alhajri, Shuchi Nagar, Tahani Mazyad Almutairi, Rupesh V. Chikhale, Surajit Ghosh, Hans Raj Bhat, Ataul Islam, Fatmah A.S. Alasmary, Anshul Shakya

Publikováno v: Molecular Diversity

Abstract Transmembrane protease serine-2 (TMPRSS2) is a cell-surface protein expressed by epithelial cells of specific tissues including those in the aerodigestive tract. It helps the entry of novel coronavirus (n-CoV) or Severe Acute Respiratory Syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b424b8446533b2a50245d81fa96e292
http://europepmc.org/articles/PMC8009078

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Molecular interaction studies of Deguelin and its derivatives with Cyclin D1 and Cyclin E in cancer cell signaling pathway: The computational approach

Autor: K. Venkateswara Swamy, Kiran Bharat Lokhande, Shuchi Nagar

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports

Deguelin is a major active ingredient and principal component in several plants and it is a potential molecule to target proteins of cancer cell signaling pathway. As a complex natural extract, deguelin interacts with various molecular targets to exe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f377621f7aedbaed26b74edcabf8839e
http://link.springer.com/article/10.1038/s41598-018-38332-6

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Biofilm inhibition and anti-quorum sensing activity of phytosynthesized silver nanoparticles against the nosocomial pathogen Pseudomonas aeruginosa

Autor: Shatavari Kulshrestha, Neelu Nawani, Swapnil Gaikwad, Viniti Vaidya, Sarika Pawar, Shuchi Nagar, Saloni Shah

Publikováno v: Biofouling. 35:34-49

Quorum sensing (QS), the communication signaling network, regulates biofilm formation and several virulence factors in Pseudomonas aeruginosa PAO1, a nosocomial opportunistic pathogen. QS is considered to be a challenging target for compounds antagon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68301dcb5fa9f14dae087cf31975510f
https://doi.org/10.1080/08927014.2018.1563686

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Akademický článek

Molecular Docking and Molecular Dynamics Simulation studies of DHFR inhibitors in Plasmodium falciparum

Autor: Prachi Bhole, Kiran Bharat Lokhande, Shuchi Nagar, K. Venkateswara Swamy

Publikováno v: Canadian Journal of Biotechnology, Vol 1, Iss Special Issue, Pp 23-23 (2017)

Malaria, caused by Plasmodium falciparum is a very common disease that causes 2.5 million deaths worldwide. This makes designing of lead molecules for malaria very exigent. DHFR has been known to be one of the major targets of antimalarial drug thera

Externí odkaz: https://doaj.org/article/10880366cc814cb9a538c95cf5c07e4e

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