Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Shucheng Hua"'
Publikováno v:
Redox Biology, Vol 77, Iss , Pp 103388- (2024)
Background: Pyroptosis is an inflammatory form of regulated necrosis that has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD). However, the role of lipid peroxidation in pyroptosis and its underlying mechanisms in
Externí odkaz:
https://doaj.org/article/50fc5573ba8e4021beba66de6a245048
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117359- (2024)
Sepsis, a frequently fatal condition, emerges from an exaggerated inflammatory response to infection, resulting in multi-organ dysfunction and alarmingly high mortality rates. Despite the urgent need for effective treatments, current therapeutic opti
Externí odkaz:
https://doaj.org/article/1a613cc7de214a7eb608fc7bc0655600
Publikováno v:
Cancer Medicine, Vol 12, Iss 19, Pp 19777-19793 (2023)
Abstract Objectives Lung cancer is a major public health concern and represents the most common cause of cancer‐related death worldwide. Among eukaryotes, the G protein‐coupled receptor (GPCR) family stands as the largest group of membrane protei
Externí odkaz:
https://doaj.org/article/acac25e4697f4983be18a102dac6a064
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0296829 (2024)
Lung adenocarcinoma (LUAD) has a poor prognosis. Circadian genes such as TIMELESS have been associated with several pathologies, including cancer. The expression of TIMELESS and the relationship between TIMELESS, infiltration of tumors and prognosis
Externí odkaz:
https://doaj.org/article/591b5df2a2a94ed5ae0d086d5b520f21
Autor:
Jinghua Yu, Wenyan Zhang, Wenbo Huo, Xiangling Meng, Ting Zhong, Ying Su, Yumeng Liu, Jinming Liu, Zengyan Wang, Fengmei Song, Shuxia Zhang, Zhaolong Li, Xiaoyan Yu, Xiaofang Yu, Shucheng Hua
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 241-257 (2022)
Numerous viruses manipulate host factors for viral production. We demonstrated that human enterovirus A71 (EVA71), a primary causative agent for hand, foot, and mouth disease (HFMD), increased the level of the DNA damage response (DDR) marker γ-H2AX
Externí odkaz:
https://doaj.org/article/a627954e76db4f469511963af0e7b55d
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
In recent years, the role of ferroptosis in pulmonary fibrosis has garnered increasing interest as a potential therapeutic target. Pulmonary fibrosis is a pathological process characterized by the accumulation of extracellular matrix in affected lung
Externí odkaz:
https://doaj.org/article/b077df115c76459e8a5e153933614b5d
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 22 (2024)
Understanding the pathogenesis of different phenotypes of asthma, including glucocorticoid-dependent and glucocorticoid-resistant asthma, is crucial for the development of effective treatments. Autophagy, a fundamental cellular process involved in ce
Externí odkaz:
https://doaj.org/article/0a6e326939d5495eb7faa58eb1a3a821
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
As a highly conserved, multifunctional protein with multiple domains, p62/SQSTM1 plays a crucial role in several essential cellular activities, particularly selective autophagy. Recent research has shown that p62 is crucial in eradicating intracellul
Externí odkaz:
https://doaj.org/article/091b0d3f5057404694cc78f4a855c9c0
Publikováno v:
Cancer Medicine, Vol 10, Iss 7, Pp 2396-2422 (2021)
Abstract Lung cancer is the leading cause of cancer‐related mortality both in men and women and accounts for 18.4% of all cancer‐related deaths. Although advanced therapy methods have been developed, the prognosis of lung cancer patients remains
Externí odkaz:
https://doaj.org/article/6b21051dd5a149d6af06659a4d23c971
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 1240-1249 (2020)
Eight members of a big family with laboratory-confirmed COVID-19 pneumonia were admitted to First Hospital of Jilin University, Changchun, China, from 28 January to 5 February 2020. The clinical records, laboratory results, and chest computed tomogra
Externí odkaz:
https://doaj.org/article/8906773a4e3e484cadd3894001ffa673