Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Shucheng Gu"'
Publikováno v:
Oncology Letters
Drug resistance is a significant obstacle when treating triple-negative breast cancer (TNBC). Several studies have demonstrated that microRNAs (miRNAs) have essential roles in regulating drug resistance in different types of cancer. miR-33a-5p has pr
Autor:
Shucheng, Gu1 (AUTHOR), Chunkang, Chang1 (AUTHOR) changchunkang7010@aliyun.com, Youshan, Zhao1 (AUTHOR), Juan, Guo1 (AUTHOR), Chengming, Fei1 (AUTHOR), Xi, Zhang1 (AUTHOR), Chao, Xiao1 (AUTHOR), Xiao, Li1 (AUTHOR)
Publikováno v:
Cancer Investigation. Apr2015, Vol. 33 Issue 4, p98-106. 9p.
Autor:
Qi He, Yujuan Yang, Youshan Zhao, Juan Guo, Shucheng Gu, Zheng Zhang, Chunkang Chang, Yan Zhang, Feng Xu, Lingyun Wu, Xiao Li
Publikováno v:
European Journal of Haematology. 90:375-384
Introduction Lower risk myelodysplastic syndromes (MDSs) are characterised by increased apoptosis of haematopoietic cells in the bone marrow (BM). The mechanism driving this excessive apoptosis involves multiple immune molecules, including inflammato
Autor:
Shucheng Gu, Youshan Zhao, Chao Xiao, Chunkang Chang, Juan Guo, Feng Xv, Xiao Li, Chengming Fei, Yanjun Xv
Publikováno v:
Hematology (Amsterdam, Netherlands). 22(1)
In order to gain an insight into labile plasma iron (LPI) in iron metabolism microenvironment in MDS.We performed ELISA, quantitative real-time polymerase chain reaction, flow cytometry, MRI T2* assays to test LPI, iron biochemical parameters, and li
Autor:
Juan Guo, Chengming Fei, Chunkang Chang, Xi Zhang, Youshan Zhao, Shucheng Gu, Xiao Li, Yao Zhang
Publikováno v:
Tumor Biology. 34:165-172
The identification of epigenetically inactivated tumor suppressor genes may shed additional light on the pathogenesis of myelodysplastic syndromes (MDS) and lead to the identification of potential therapeutic targets for demethylating agents. In this
Publikováno v:
Hematology. 17:275-282
p73, a tumor suppressor gene with significant homology to p53, is hypermethylated in a high percentage of NK-cell lymphoma and B-cell lymphomas patients. Given these data, we sought to study the role of p73 methylation in the pathogenesis of myelodys
Publikováno v:
Hematology. 17:220-228
p57kip2 is considered as a candidate tumor suppressor gene involvement in cell cycle control. In this study, we explored the expression of p57kip2 in various myelodysplastic syndrome (MDS) subsets by real-time quantitative PCR, as well as the relatio
Autor:
Feng Xu, Yang Zhu, Shucheng Gu, Jiying Su, Zheng Zhang, Juan Guo, Xiao Li, Liyu Zhou, Lu-Xi Song, Chengming Fei, Chunkang Chang, Wen-Hui Shi, Dong Wu, Youshan Zhao, Qi He, Li Liu, Lingyun Wu, Chao Xiao
Publikováno v:
Nature Communications
The progressive mechanism underlying myelodysplastic syndrome remains unknown. Here we identify ROBO1 and ROBO2 as novel progression-related somatic mutations using whole-exome and targeted sequencing in 6 of 16 (37.5%) paired MDS patients with disea
Autor:
Chengming, Fei, Juan, Guo, Youshan, Zhao, Shucheng, Gu, Sida, Zhao, Xiao, Li, Chunkang, Chang
Publikováno v:
American journal of translational research. 7(10)
Previous studies have demonstrated that bone marrow mesenchymal stromal cells (BMMSCs) from patients with myelodysplastic syndromes (MDS) display defective proliferative potential and impaired osteogenic differentiation ability. However, the underlyi
Autor:
Chengming Fei, Xiao Li, Youshan Zhao, Juan Guo, Jiying Su, Chunkang Chang, Qi He, Shucheng Gu
Publikováno v:
Hematology (Amsterdam, Netherlands). 21(3)
The aim of this study was to evaluate the prognostic impact of immunophenotyping in patients with multiple myeloma (MM), as well as other markers of disease, such as serum hyaluronan and cytogenetic aberrancies.We have prospectively analyzed the prog