Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shubin Shahab"'
Autor:
Shubin Shahab, Jason Fangusaro
Publikováno v:
Clinics in Perinatology. 48:35-51
Central nervous system (CNS) tumors, including brain and spinal cord tumors, are the most common solid tumors of childhood. Within the neonatal population, however, CNS tumors are relatively rare. These often carry a dismal prognosis in part due to t
Autor:
Eric H. Raabe, Harpreet Kaur, Shubin Shahab, Charles G. Eberhart, Heather Sweeney, Jeffrey Rubens
Publikováno v:
J Neuropathol Exp Neurol
Atypical teratoid/rhabdoid (AT/RT) tumors are the most common malignant brain tumor of infancy and have a poor prognosis. We have previously identified very high expression of LIN28A and/or LIN28B in AT/RT tumors and showed that AT/RT have correspond
Publikováno v:
Neuro-Oncology. 24:vii289-vii289
Medulloblastoma (MB) is the most common pediatric brain malignancy. MB comprises 5 major subgroups known as WNT, SHH p53wt, SHH p53mut, Group 3 and Group 4. Among the four MB subgroups SHH group is the most dominant molecular subgroup in infants and
CSIG-34. LIN28B-LET-7-PBK PATHWAY IS AN IMPORTANT REGULATOR OF GROUP 3 MEDULLOBLASTOMA PROLIFERATION
Autor:
Shubin Shahab, Jessica Sun, Haritha Kunhiraman, Matthew Schneiderjan, Kyle Juraschka, Sachin Kumar, Michael Taylor, Tobey MacDonald, Anna Kenney
Publikováno v:
Neuro-Oncology. 24:vii46-vii46
Children with Group 3 medulloblastoma (MB) have a very poor long-term outcome and many do not survive beyond 5 years. Several drivers for Group 3 MB have been identified but none have resulted in targeted therapy to date. LIN28B is a stem cell factor
Publikováno v:
Neuro-Oncology. 24:i121-i121
BACKGROUND: Children with Group 3 medulloblastoma (MB) have a very poor long-term outcome and many do not survive beyond 5 years. Several drivers for Group 3 MB have been identified but none have resulted in targeted therapy to date. LIN28B is a stem
Autor:
Shubin Shahab, Casey Zhu, Shun Wen Chen, Charles G. Eberhart, Karina Negron, Justin Hanes, Eric H. Raabe, Jung Soo Suk, Divya Rao
Publikováno v:
Drug Deliv Transl Res
Several generations of poly(β-amino ester) (PBAE) polymers have been developed for efficient cellular transfection. However, PBAE-based gene vectors, similar to other cationic materials, cannot readily provide widespread gene transfer in the brain d
Autor:
Tobey J. MacDonald, Kyle Juraschka, Jo Lynne Rokita, Robert W. Schnepp, Shubin Shahab, Anna Kenney, Michael D. Taylor, Sachin Kumar
Publikováno v:
Cancer Research. 81:3024-3024
Medulloblastoma (MB) is the most common pediatric malignant brain tumor and is currently divided into WNT, SHH, Group 3 and Group 4 subtypes. Even with multimodal chemotherapy, radiotherapy and surgery, many children with Group 3 MBs do not survive.
Publikováno v:
Neuro-Oncology
Medulloblastoma (MB) is the most common pediatric malignant brain tumor and is currently divided into WNT, SHH, Group 3 and Group 4 subtypes. Even with multimodal chemotherapy, radiotherapy and surgery, many children with Group 3 MBs do not survive.
Autor:
Shubin Shahab, Emily Dunn, Patience Obasaju, Jeffrey S. Dome, LiQun Jiang, Christine A. Pratilas, Daniel S. Rhee, Pedram Argani, Alan D. Friedman
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Wilms tumor (WT) is the most common renal malignancy of childhood and accounts for 6% of all childhood malignancies. With current therapies, the 5-yr overall survival (OS) for children with unilateral favorable histology WT is greater than 85%. The p
Atypical teratoid/rhabdoid (AT/RT) tumors are a class of malignant CNS tumors disproportionately affecting children with limited therapeutic options. Our group has previously demonstrated that the MAP kinase pathway is altered in a large proportion o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d466cbdadab8247cdfa92317e99e4b0
https://europepmc.org/articles/PMC6477334/
https://europepmc.org/articles/PMC6477334/