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BackgroundObservational studies suggest a connection between ACE2 (angiotensin-converting enzyme 2) and lung cancer. However, it's not apparent if confounding variables are interfering with the link. Therefore, we aimed to define the relationships be

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The benefit and risk of PD-1/PD-L1 inhibitors plus anti-angiogenic agents as second or later-line treatment for patients with advanced non-small-cell lung cancer: a systematic review and single-arm meta-analysis of prospective clinical trials

Autor: Shubin Chen, Wanying Mo, Wei Jiang, Shaozhang Zhou, Haijie Gan, Qitao Yu

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

BackgroundPrevious studies revealed that Programmed cell death protein 1 (PD-1)/Programmed cell death-Ligand protein 1 (PD-L1) inhibitors plus anti-angiogenic agents had extensive anti-tumor activities. However, almost all studies on the efficacy and

Externí odkaz: https://doaj.org/article/5a4fa8add55842fc97e91f63fb903c54

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Ceruminous adenoma of the external auditory canal: 9 cases series with imaging and pathologic findings

Autor: Yifan Yang, Honggang Liu, Jugao Fang, Yongxin Li, Shubin Chen

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

ObjectivesCeruminous adenoma is a rare benign tumor of the external auditory canal. This study aimed to present the clinical characteristics, imaging findings, pathological results and the management outcomes of the ceruminous adenoma.Study designRet

Externí odkaz: https://doaj.org/article/7f76b7633f824232a503eb2d526f08ff

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Rechallenge with EGFR-TKI after failure of immunotherapy is considered an effective treatment for advanced lung adenocarcinoma patients with EGFR exon 19 deletion: a case report

Autor: Shubin Chen, Qitao Yu, Wei Jiang, Yukun Lu, Yun Zhao, Huilin Wang

Publikováno v: Frontiers in Medicine, Vol 10 (2023)

In advanced lung adenocarcinoma patients with epidermal growth factor receptor (EGFR) mutation, epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) have an excellent and long-lasting therapeutic response; however, virtually all pa

Externí odkaz: https://doaj.org/article/2a2794ac52994278a0057e81042090de

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GWAS and Meta-QTL Analysis of Yield-Related Ear Traits in Maize

Autor: Fu Qian, Jianguo Jing, Zhanqin Zhang, Shubin Chen, Zhiqin Sang, Weihua Li

Publikováno v: Plants, Vol 12, Iss 22, p 3806 (2023)

Maize ear traits are an important component of yield, and the genetic basis of ear traits facilitates further yield improvement. In this study, a panel of 580 maize inbred lines were used as the study material, eight ear-related traits were measured

Externí odkaz: https://doaj.org/article/055d8ff2025f4187b39f764c29e09ac8

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Upper Bounded Minimal Solution of the Max-Min Fuzzy Relation Inequality System

Autor: Shubin Chen, Khizar Hayat, Xiaopeng Yang

Publikováno v: IEEE Access, Vol 10, Pp 84384-84397 (2022)

Resolution of the minimal solutions plays an important role in the research on fuzzy relation equations or inequalities system. Most of the existing works focused on the general minimal solutions or some specific minimal solutions that optimize parti

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