Zobrazeno 1 - 10
of 329
pro vyhledávání: '"Shubhayan, Sanatani"'
Autor:
Simona Bene Watts, Barbara Gauthier, Anders C. Erickson, Julie Morrison, Mavis Sebastian, Lawrence Gillman, Sarah McIntosh, Connie Ens, Elizabeth Sherwin, Rod McCormick, Shubhayan Sanatani, Laura Arbour
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
IntroductionCongenital Long QT Syndrome (LQTS) is common in a First Nations community in Northern British Columbia due to the founder variant KCNQ1 p.V205M. Although well characterized molecularly and clinically in adults, no data have been previousl
Externí odkaz:
https://doaj.org/article/18499b3cdaea4a0baf897ebbacd8c308
Autor:
Mikyla L. Janzen, MSc, Brianna Davies, MSc, Zachary W.M. Laksman, MD, Jason D. Roberts, MD, Shubhayan Sanatani, MD, Christian Steinberg, MD, Rafik Tadros, MD, Julia Cadrin-Tourigny, MD, Ciorsti MacIntyre, MD, Joseph Atallah, MD, Anne Fournier, MD, Martin S. Green, MD, Robert Hamilton, MD, Habib R. Khan, MBBS, PhD, Shane Kimber, MD, Steven White, MD, PhD, Jacqueline Joza, MD, Bhavanesh Makanjee, MD, Erkan Ilhan, MD, David Lee, MD, Simon Hansom, MD, Alexios Hadjis, MD, Laura Arbour, MD, Richard Leather, MD, Colette Seifer, MD, Paul Angaran, MD, Christopher S. Simpson, MD, Jeffrey S. Healey, MD, Martin Gardner, MD, Mario Talajic, MD, Andrew D. Krahn, MD
Publikováno v:
CJC Open, Vol 5, Iss 4, Pp 268-284 (2023)
Inherited arrhythmia syndromes are rare genetic conditions that predispose seemingly healthy individuals to sudden cardiac arrest and death. The Hearts in Rhythm Organization is a multidisciplinary Canadian network of clinicians, researchers, patient
Externí odkaz:
https://doaj.org/article/a38f80ee67804815b49b83c92c51af13
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Sudden cardiac death (SCD) is a rare and devastating event in children and remains a leading cause of death in young athletes. Channelopathies and cardiomyopathies, in particular long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tach
Externí odkaz:
https://doaj.org/article/a22bb8f0e6aa473285c8657b528bd7d3
Autor:
Sonia Franciosi, PhD, Dominic J. Abrams, MBBS, MD, MBA, Jodie Ingles, PhD, MPH, Shubhayan Sanatani, MD, FRCPC, FHRS, CCDS
Publikováno v:
CJC Pediatric and Congenital Heart Disease, Vol 1, Iss 2, Pp 45-59 (2022)
Sudden cardiac arrest in the young is a rare event with a range of potential causes including cardiomyopathies, ion channelopathies, and autonomic nervous system dysfunction. Investigations into the cause involve a multidisciplinary team, including c
Externí odkaz:
https://doaj.org/article/aca32cec006a4b7f825356382753943d
Autor:
Chi Hung Chen, MD, Astrid-Marie De Souza, MSc, Sonia Franciosi, PhD, Kevin C. Harris, MD, Shubhayan Sanatani, MD
Publikováno v:
CJC Pediatric and Congenital Heart Disease, Vol 1, Iss 2, Pp 80-85 (2022)
Background: Physical activity (PA) is important for cardiovascular health as well as social and emotional well-being of children. Patients with long QT syndrome (LQTS) often face PA restrictions and are often prescribed beta-blockers for disease mana
Externí odkaz:
https://doaj.org/article/b2c33f90aab141e5a879f4f78dcc571b
Autor:
Nathan Wei, Avani Lamba, BS, Sonia Franciosi, PhD, Ian H. Law, BSE, MD, FHRS, Luis A. Ochoa, MD, Christopher L. Johnsrude, MD, MS, Sit Yee Kwok, MBChB, CEPS-P, Teng Hong Tan, MBBS, Santokh S. Dhillon, MBBS, MD, FHRS, CCDS, Anne Fournier, MD, Stephen P. Seslar, MD, PhD, CCDS, CEPS-P, Elizabeth A. Stephenson, MD, FHRS, CEPS-P, Andrew D. Blaufox, MD, FHRS, CEPS-P, Michel Cabrera Ortega, MD, Jeffrey N. Bone, MSc, Ash Sandhu, BS, Carolina A. Escudero, MD, MS, Shubhayan Sanatani, BS, MD, FHRS, CCDS
Publikováno v:
CJC Pediatric and Congenital Heart Disease, Vol 1, Iss 1, Pp 11-22 (2022)
Background: Several medication choices are available for acute and prophylactic treatment of refractory supraventricular tachycardia (SVT) in infants. There are almost no controlled trials, and medication choices are not necessarily evidence based. O
Externí odkaz:
https://doaj.org/article/f874c503afa1496ebf7e5af3bb422a72
Autor:
Thomas M. Roston, MD, PhD, Sunjidatul Islam, MBBS, MSc, Nathaniel M. Hawkins, MBChB, MD, MPH, Zachary W. Laksman, MD, MSc, Shubhayan Sanatani, MD, Andrew D. Krahn, MD, Roopinder Sandhu, MD, MPH, Padma Kaul, PhD
Publikováno v:
CJC Open, Vol 4, Iss 1, Pp 65-74 (2022)
Background: Previous studies on lone/unexplained atrial fibrillation and atrial flutter (AF) did not exclude patients with contemporary secondary AF triggers. We characterized unexplained AF using a strict definition, and compared it to secondary AF.
Externí odkaz:
https://doaj.org/article/01e36a15d80c4dd6a1d1d0661d983825
Autor:
Lauren A. Yee, Hui‐Chen Han, Brianna Davies, Charles M. Pearman, Zachary W. M. Laksman, Jason D. Roberts, Christian Steinberg, Rafik Tadros, Julia Cadrin‐Tourigny, Christopher S. Simpson, Martin Gardner, Ciorsti MacIntyre, Laura Arbour, Richard Leather, Anne Fournier, Martin S. Green, Shane Kimber, Paul Angaran, Shubhayan Sanatani, Jacqueline Joza, Habib Khan, Jeffrey S. Healey, Joseph Atallah, Colette Seifer, Andrew D. Krahn
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 18 (2022)
Background Diagnosis of congenital long‐QT syndrome (LQTS) is complicated by phenotypic ambiguity, with a frequent normal‐to‐borderline resting QT interval. A 3‐step algorithm based on exercise response of the corrected QT interval (QTc) was
Externí odkaz:
https://doaj.org/article/74f68265baa04c09ab267ca8700c9a52
Autor:
Ming Chang Liu, Matthew A. Tester, BSc, Sonia Franciosi, PhD, Andrew D. Krahn, MD, FHRS, Martin J. Gardner, MD, FRCPC, Jason D. Roberts, MD, MAS, Shubhayan Sanatani, MD, FRCPC, FHRS, CCDS
Publikováno v:
CJC Open, Vol 3, Iss 3, Pp 285-291 (2021)
Background: The etiology of sudden cardiac arrest (SCA) in individuals without known cardiovascular heart disease remains elusive in nearly half of all patients after systematic testing. We investigated the relationship between stressful life events
Externí odkaz:
https://doaj.org/article/5102e790a8444acd8c4c34d1752b1274
Autor:
Britt I. Drögemöller, Galen E.B. Wright, Jessica Trueman, Kaitlyn Shaw, Michelle Staub, Shahnaz Chaudhry, Fudan Miao, Michelle Higginson, Gabriella S.S. Groeneweg, James Brown, Laura A. Magee, Simon D. Whyte, Nicholas West, Sonia M. Brodie, Geert ’t Jong, Sara Israels, Howard Berger, Shinya Ito, Shahrad R. Rassekh, Shubhayan Sanatani, Colin J.D. Ross, Bruce C. Carleton
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 148, Iss , Pp 112684- (2022)
Background: Ondansetron is a highly effective antiemetic for the treatment of nausea and vomiting. However, this medication has also been associated with QT prolongation. Pharmacogenomic information on therapeutic response to ondansetron exists, but
Externí odkaz:
https://doaj.org/article/c4294f7b02a8413280155b30a5305cc8