Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shubham Banga"'
Publikováno v:
Mechanisms of ageing and development. 206
Chronic low-grade elevations of blood-borne cytokines/chemokines in older age tend to associate with frailty in humans. This persistent inflammation is often called "inflammageing" and likely contributes to frailty progression. Preclinical models suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009b1236a491f05d0ecc2e17c1762c2e
https://pubmed.ncbi.nlm.nih.gov/35835224
https://pubmed.ncbi.nlm.nih.gov/35835224
Publikováno v:
The Lancet Healthy Longevity. 3:e83-e84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baef2d61135ee5b2eff3406eb76836c6
https://doi.org/10.1016/s2666-7568(22)00008-3
https://doi.org/10.1016/s2666-7568(22)00008-3
Publikováno v:
Mechanisms of Ageing and Development. 198:111523
We investigated whether maladaptive, age-associated changes in heart structure and function were linked to circulating testosterone levels. Male C57BL/6 mice had a gonadectomy (GDX) or sham surgery at 4 weeks and effects of GDX on the heart were exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b9c1bee97aa41746c8ff735b534047
https://doi.org/10.1016/j.mad.2021.111523
https://doi.org/10.1016/j.mad.2021.111523
Publikováno v:
Circulation Research. 125
Objective: Low circulating testosterone levels are correlated with heart diseases in older adults. The belief that low testosterone contributes to poor health and promotes frailty has dramatically increased testosterone prescriptions in recent years.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fd8ac8a7343cc61af3e4160685e6a8b
https://doi.org/10.1161/res.125.suppl_1.443
https://doi.org/10.1161/res.125.suppl_1.443
Publikováno v:
Circulation Research. 125
Clinical studies suggest that testosterone modulates the electrical activity of the heart and that low testosterone promotes cardiac arrhythmias. Here we investigated cellular mechanisms involved in the electrophysiological effects of chronic testost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a917076d7bb6ddc8589a42850d79ecd
https://doi.org/10.1161/res.125.suppl_1.809
https://doi.org/10.1161/res.125.suppl_1.809
Autor:
Robert A. Rose, Omar Ayaz, Susan E. Howlett, W. Glen Pyle, Stefan Heinze-Milne, Shubham Banga
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 316(4)
The impact of long-term gonadectomy (GDX) on cardiac contractile function was explored in the setting of aging. Male mice were subjected to bilateral GDX or sham operation (4 wk) and investigated at 16–18 mo of age. Ventricular myocytes were field
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba2d932f03a7a6cffb1dfbf766dbdc6
https://pubmed.ncbi.nlm.nih.gov/30681369
https://pubmed.ncbi.nlm.nih.gov/30681369
Publikováno v:
Mechanisms of ageing and development. 179
In clinical medicine, the concept of frailty is viewed as a state of high vulnerability to adverse health outcomes in people of the same age. Frailty is an important challenge because the loss of physiological reserve means that even minor stressors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b18504a983c5f245693fd6dd223e58
https://pubmed.ncbi.nlm.nih.gov/30703384
https://pubmed.ncbi.nlm.nih.gov/30703384