Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Shubhada R. Hegde"'
Autor:
Priyansha Raj Sinha, Shubhada R. Hegde, Ruchika Mittal, Chikkamagaluru Chandrashekhar Jagat, Ullas Gowda, Rathna Chandrashekhar, Gayathri Muthaiah, Samer Shamshad, Mohammed Mudassar Chanda, Vishweshwar Ganji, Kalyani Putty, Divakar Hemadri
Publikováno v:
Pathogens, Vol 13, Iss 11, p 944 (2024)
The bluetongue virus (BTV), transmitted by biting midges, poses a significant threat to livestock globally. This orbivirus induces bluetongue disease, leading to substantial economic losses in the agricultural sector. The current control measures hav
Externí odkaz:
https://doaj.org/article/1cf1c66ac354463f91f5b391e88abddb
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Bioinformatic studies on small proteins are under-represented due to difficulties in annotation posed by their small size. However, recent discoveries emphasize the functional significance of small proteins in cellular processes including cell signal
Externí odkaz:
https://doaj.org/article/e755d389fcee4e5ca66bd4b37b6f3159
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract An increased surge of -omics data for the diseases such as cancer allows for deriving insights into the affiliated protein interactions. We used bipartite network principles to build protein functional associations of the differentially regu
Externí odkaz:
https://doaj.org/article/6cee77b5d1654b368370000e93496267
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Tuberculosis remains one of the leading causes of morbidity and mortality worldwide. Therefore, understanding the pathophysiology of Mycobacterium tuberculosis is imperative for developing new drugs. Post-transcriptional regulatio
Externí odkaz:
https://doaj.org/article/c37b7bd3f20743ef8f0ffdf4283f7f9e
Autor:
Shubhada R. Hegde
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
With prolonged therapy and increased instances of drug resistance, tuberculosis is viewed as a serious infectious disease causing high mortality. Emerging concepts in Mycobacterium tuberculosis pathogenicity include biofilm formation, which endows ba
Externí odkaz:
https://doaj.org/article/25363e7bf5e642a19ff0b08a4b523095
Autor:
Ezaz Ahmad, Anirban Mitra, Wareed Ahmed, Varsha Mahapatra, Shubhada R. Hegde, Claudia Sala, Stewart T. Cole, Valakunja Nagaraja
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1866:194923
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::991741d2c584a7b69d034696d0fcb6f8
https://doi.org/10.1016/j.bbagrm.2023.194923
https://doi.org/10.1016/j.bbagrm.2023.194923
Autor:
Wareed Ahmed, Claudia Sala, Shubhada R Hegde, Rajiv Kumar Jha, Stewart T Cole, Valakunja Nagaraja
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006754 (2017)
Movement of the transcription machinery along a template alters DNA topology resulting in the accumulation of supercoils in DNA. The positive supercoils generated ahead of transcribing RNA polymerase (RNAP) and the negative supercoils accumulating be
Externí odkaz:
https://doaj.org/article/6d4567ad243846628ffff8c2c9e88a87
Publikováno v:
Gene. 755
Large-scale -omics data now allows for investigating genome-wide functional elements. Using RNA-Seq data, we tested the expression of 134 pseudogenes which do not show duplicated protein coding genes in the M. smegmatis genome. We observe significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6994884f77389c35890b459e9e738109
https://pubmed.ncbi.nlm.nih.gov/32565322
https://pubmed.ncbi.nlm.nih.gov/32565322
Publikováno v:
BMC Genomics
BMC Genomics, Vol 21, Iss 1, Pp 1-12 (2020)
BMC Genomics, Vol 21, Iss 1, Pp 1-12 (2020)
Background Tuberculosis remains one of the leading causes of morbidity and mortality worldwide. Therefore, understanding the pathophysiology of Mycobacterium tuberculosis is imperative for developing new drugs. Post-transcriptional regulation plays a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11bb4fae70ae232f2d5770db1e1aa18
http://europepmc.org/articles/PMC7029489
http://europepmc.org/articles/PMC7029489
Publikováno v:
Biochemical and biophysical research communications. 522(1)
In Escherichia coli, G/C-rich hairpin structure followed by a U-tract in the 3′ region of the nascent RNA are crucial determinants for intrinsic or factor independent transcription termination. In mycobacteria, there is a scarcity of such intrinsic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1b74bca65fca3805530d8f9234abb9
https://pubmed.ncbi.nlm.nih.gov/31759631
https://pubmed.ncbi.nlm.nih.gov/31759631