Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shubhada Godbole"'
Autor:
Stephen M Beckstrom-Sternberg, Raymond K Auerbach, Shubhada Godbole, John V Pearson, James S Beckstrom-Sternberg, Zuoming Deng, Christine Munk, Kristy Kubota, Yan Zhou, David Bruce, Jyothi Noronha, Richard H Scheuermann, Aihui Wang, Xianying Wei, Jianjun Wang, Jicheng Hao, David M Wagner, Thomas S Brettin, Nancy Brown, Paul Gilna, Paul S Keim
Publikováno v:
PLoS ONE, Vol 2, Iss 9, p e947 (2007)
Francisella tularensis is the causative agent of tularemia, which is a highly lethal disease from nature and potentially from a biological weapon. This species contains four recognized subspecies including the North American endemic F. tularensis sub
Externí odkaz:
https://doaj.org/article/a8549ea117e948b5b72c6489bc97a40c
Autor:
Roger L. Chang, Richard H. Scheuermann, Christopher N. Larsen, Catherine A. Macken, Kevin Biersack, Shubhada Godbole, Adolfo García-Sastre, Jyothi M. Noronha, R. Burke Squires, Edward B. Klem, Victoria Hunt
Publikováno v:
Nucleic Acids Research
The BioHealthBase Bioinformatics Resource Center (BRC) (http://www.biohealthbase.org) is a public bioinformatics database and analysis resource for the study of specific biodefense and public health pathogens-Influenza virus, Francisella tularensis,
Publikováno v:
Journal of Molecular Biology. 296:217-228
The changes in the free energy of the denatured state of a set of yeast iso-1-cytochrome c variants with single surface histidine residues have been measured in 3 M guanidine hydrochloride. The thermodynamics of unfolding by guanidine hydrochloride i
Autor:
Bruce E. Bowler, Shubhada Godbole
Publikováno v:
Biochemistry. 38:487-495
Previous work on a Lys 73 --> His (H73) variant of iso-1-cytochrome c at pH 7.5 [Godbole et al. (1997) Biochemistry 36, 119-126] showed that this variant unfolds through a nativelike intermediate that has properties consistent with replacement of the
Publikováno v:
Journal of Molecular Biology. 275:719-724
In previous work, heme ligation effects on the folding of cytochrome c have been attributed to histidine side-chains. A variant of yeast iso-1-cytochrome c designated TM, which lacks all histidine residues except His18, still shows evidence of denatu
Autor:
Shubhada Godbole, Bruce E. Bowler
Publikováno v:
Journal of Molecular Biology. 268:816-821
Iso-1-cytochrome c has been engineered to remove all histidine residues not involved in heme ligation in the native state to produce a variant designated TM. Single histidine residues were then introduced at positions 26, TM + His26, and 54, TM + His
Publikováno v:
Biochemistry. 36:119-126
In this paper we report thermodynamic studies on a variant of yeast iso-1-cytochrome c in which a surface lysine residue at position 73 has been replaced with a histidine (H73). Guanidine hydrochloride denaturation studies monitored by circular dichr
Autor:
Richard H. Scheuermann, Ravi D. Barabote, Paul D. Fey, Justin J. Jay, Jeniffer L. Engle, Gary Xie, Steven H. Hinrichs, Thomas Brettin, Liwel W. Zhou, Jyothi M. Noronha, Michael P. Dempsey, Christine Lion, Shubhada Godbole
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 9, p e7041 (2009)
PLoS ONE, Vol 4, Iss 9, p e7041 (2009)
Francisella tularensis subspecies holarctica FTNF002-00 strain was originally obtained from the first known clinical case of bacteremic F. tularensis pneumonia in Southern Europe isolated from an immunocompetent individual. The FTNF002-00 complete ge
Autor:
Rafael A. Nieves, Michael E. Himmel, Todd B. Vinzant, Stephen R. Decker, Shubhada Godbole, William S. Adney, Steven R. Thomas, John O. Baker
Publikováno v:
Biotechnology progress. 15(5)
Pichia pastoris was transformed with the Trichoderma reesei cbh1 gene, and the recombinant enzyme was purified and analyzed kinetically and by circular dichroism. The P. pastoris rCBH I was recognized by MoAb raised to T. reesei CBH I but was found i
Autor:
Jianjun Wang, Raymond K. Auerbach, Nancy C. Brown, Yan Zhou, Aihui Wang, Thomas Brettin, Richard H. Scheuermann, Xianying Wei, Christine Munk, Paul Keim, Paul Gilna, Jicheng Hao, Zuoming Deng, Stephen M. Beckstrom-Sternberg, Jyothi M. Noronha, David Bruce, Shubhada Godbole, Kristy Kubota, John V. Pearson, James S. Beckstrom-Sternberg, David M. Wagner
Publikováno v:
PLoS ONE
PLoS ONE, Vol 2, Iss 9, p e947 (2007)
PLoS ONE, Vol 2, Iss 9, p e947 (2007)
Francisella tularensis is the causative agent of tularemia, which is a highly lethal disease from nature and potentially from a biological weapon. This species contains four recognized subspecies including the North American endemic F. tularensis sub