Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Shubhabrata Mukherjee"'
Autor:
Donghui Yan, Bowen Hu, Burcu F Darst, Shubhabrata Mukherjee, Brian W Kunkle, Yuetiva Deming, Logan Dumitrescu, Yunling Wang, Adam Naj, Amanda Kuzma, Yi Zhao, Hyunseung Kang, Sterling C Johnson, Cruchaga Carlos, Timothy J Hohman, Paul K Crane, Corinne D Engelman, Alzheimer’s Disease Genetics Consortium (ADGC), Qiongshi Lu
Publikováno v:
eLife, Vol 12 (2024)
Rich data from large biobanks, coupled with increasingly accessible association statistics from genome-wide association studies (GWAS), provide great opportunities to dissect the complex relationships among human traits and diseases. We introduce BAD
Externí odkaz:
https://doaj.org/article/70e5d04b97aa44e69655821a17499202
Autor:
Moonil Kang, Ting Fang Alvin Ang, Sherral A. Devine, Richard Sherva, Shubhabrata Mukherjee, Emily H. Trittschuh, Laura E. Gibbons, Phoebe Scollard, Michael Lee, Seo-Eun Choi, Brandon Klinedinst, Connie Nakano, Logan C. Dumitrescu, Alaina Durant, Timothy J. Hohman, Michael L. Cuccaro, Andrew J. Saykin, Walter A. Kukull, David A. Bennett, Li-San Wang, Richard P. Mayeux, Jonathan L. Haines, Margaret A. Pericak-Vance, Gerard D. Schellenberg, Paul K. Crane, Rhoda Au, Kathryn L. Lunetta, Jesse B. Mez, Lindsay A. Farrer
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-22 (2023)
Abstract Background More than 75 common variant loci account for only a portion of the heritability for Alzheimer’s disease (AD). A more complete understanding of the genetic basis of AD can be deduced by exploring associations with AD-related endo
Externí odkaz:
https://doaj.org/article/fe39bfd5b90d4d70a686b48ed5244454
Autor:
Cameron B Haas, Kristina M Jordahl, Robin M Nance, Bridget M Whitney, Lu Wang, Joseph A C Delaney, Stephanie Ruderman, Tongqiu Jia, Wm Christopher Mathews, Michael S Saag, Sulggi A Lee, Sonia Napravnik, Jeffrey M Jacobson, Geetanjali Chander, Elizabeth M McCall, Richard D Moore, Kenneth H Mayer, Shubhabrata Mukherjee, Won Jun Lee, Paul K Crane, Heidi Crane, Inga Peter, Sara Lindström
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292068 (2023)
BackgroundThe prevalence of substance use in people with HIV (PWH) in the United States is higher than in the general population and is an important driver of HIV-related outcomes. We sought to assess if previously identified genetic associations tha
Externí odkaz:
https://doaj.org/article/a712c4f5e3504e33af83e297d309a195
Autor:
Adam J. Dugan, Peter T. Nelson, Yuriko Katsumata, Lincoln M. P. Shade, Kevin L. Boehme, Merilee A. Teylan, Matthew D. Cykowski, Shubhabrata Mukherjee, John S. K. Kauwe, Timothy J. Hohman, Julie A. Schneider, Alzheimer’s Disease Genetics Consortium, David W. Fardo
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) is the most prevalent subtype of TDP-43 proteinopathy, affecting up to 1/3rd of aged persons. LATE-NC often co-occurs with hippocampal sclerosis (HS) patho
Externí odkaz:
https://doaj.org/article/72aff6c422274975afc0f86f16c43120
Autor:
Shubhabrata Mukherjee, Taesang Choi, Md Tajul Islam, Baek‐Young Choi, Cory Beard, Seuck Ho Won, Sejun Song
Publikováno v:
ETRI Journal, Vol 42, Iss 5, Pp 689-702 (2020)
In this paper, we propose a supervised‐learning‐based spatial performance prediction (SLPP) framework for next‐generation heterogeneous communication networks (HCNs). Adaptive asset placement, dynamic resource allocation, and load balancing are
Externí odkaz:
https://doaj.org/article/849e61baad0b4adaa7780f90ac49f27f
Autor:
Colin Groot, Michel J. Grothe, Shubhabrata Mukherjee, Irina Jelistratova, Iris Jansen, Anna Catharina van Loenhoud, Shannon L. Risacher, Andrew J. Saykin, Christine L. Mac Donald, Jesse Mez, Emily H. Trittschuh, Gregor Gryglewski, Rupert Lanzenberger, Yolande A.L. Pijnenburg, Frederik Barkhof, Philip Scheltens, Wiesje M. van der Flier, Paul K. Crane, Rik Ossenkoppele
Publikováno v:
NeuroImage: Clinical, Vol 30, Iss , Pp 102660- (2021)
The clinical presentation of Alzheimer’s disease (AD) varies widely across individuals but the neurobiological mechanisms underlying this heterogeneity are largely unknown. Here, we compared regional gray matter (GM) volumes and associated gene exp
Externí odkaz:
https://doaj.org/article/85c00c7b93174f5d92709e1f0e4cf7fd
Differential trajectories of hypometabolism across cognitively-defined Alzheimer’s disease subgroups
Autor:
Colin Groot, Shannon L. Risacher, J.Q. Alida Chen, Ellen Dicks, Andrew J. Saykin, Christine L. Mac Donald, Jesse Mez, Emily H. Trittschuh, Shubhabrata Mukherjee, Frederik Barkhof, Philip Scheltens, Wiesje M. van der Flier, Rik Ossenkoppele, Paul K. Crane
Publikováno v:
NeuroImage: Clinical, Vol 31, Iss , Pp 102725- (2021)
Disentangling biologically distinct subgroups of Alzheimer’s disease (AD) may facilitate a deeper understanding of the neurobiology underlying clinical heterogeneity. We employed longitudinal [18F]FDG-PET standardized uptake value ratios (SUVRs) to
Externí odkaz:
https://doaj.org/article/f9ff498d9a524fb8bcf59d02bd62f09f
Autor:
Madeline Uretsky, Laura E. Gibbons, Shubhabrata Mukherjee, Emily H. Trittschuh, David W. Fardo, Patricia A. Boyle, C. Dirk Keene, Andrew J. Saykin, Paul K. Crane, Julie A. Schneider, Jesse Mez
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 7, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Alzheimer's disease (AD) neuropathological subtypes (limbic predominant [lpAD], hippocampal sparing [HpSpAD], and typical [tAD]), defined by relative neurofibrillary tangle (NFT) burden in limbic and cortical regions, have not b
Externí odkaz:
https://doaj.org/article/ff4e466cadfb4da390e2a876101beff0
Autor:
Nikhil Milind, Christoph Preuss, Annat Haber, Guruprasad Ananda, Shubhabrata Mukherjee, Cai John, Sarah Shapley, Benjamin A Logsdon, Paul K Crane, Gregory W Carter
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008775 (2020)
Late-Onset Alzheimer's disease (LOAD) is a common, complex genetic disorder well-known for its heterogeneous pathology. The genetic heterogeneity underlying common, complex diseases poses a major challenge for targeted therapies and the identificatio
Externí odkaz:
https://doaj.org/article/92222befc42747d7be50ca326a51ea4a
Autor:
Seo‐Eun Choi, Shubhabrata Mukherjee, Laura E. Gibbons, R. Elizabeth Sanders, Richard N. Jones, Douglas Tommet, Jesse Mez, Emily H. Trittschuh, Andrew Saykin, Melissa Lamar, Laura Rabin, Nancy S. Foldi, Sietske Sikkes, Roos J. Jutten, Evan Grandoit, Christine Mac Donald, Shannon Risacher, Colin Groot, Rik Ossenkoppele, for the Alzheimer's Disease Neuroimaging Initiative, Paul K. Crane
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Composite scores may be useful to summarize overall language or visuospatial functioning in studies of older adults. Methods We used item response theory to derive composite measures for language (ADNI‐Lan) and visuospatial fu
Externí odkaz:
https://doaj.org/article/391b3e583d5d483083711329efa0e4be