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Autor:
Shubha Sreenivasan, Soumya Nayak, Prokar Dasgupta, Richard A. G. Smith, Sudha Narayana Rao, Annapurna Vyakarnam, Oliver Hickman, Christine Galustian
Publikováno v:
British Journal of Cancer
Hickman, O J, Smith, R A, Dasgupta, P, Rao, S N, Nayak, S, Sreenivasan, S, Vyakarnam, A & Galustian, C 2016, ' Expression of two WFDC1/ps20 isoforms in prostate stromal cells induces paracrine apoptosis through regulation of PTGS2/COX-2 ', British Journal of Cancer, vol. 114, no. 11, pp. 1235–1242 . https://doi.org/10.1038/bjc.2016.91
Hickman, O J, Smith, R A, Dasgupta, P, Rao, S N, Nayak, S, Sreenivasan, S, Vyakarnam, A & Galustian, C 2016, ' Expression of two WFDC1/ps20 isoforms in prostate stromal cells induces paracrine apoptosis through regulation of PTGS2/COX-2 ', British Journal of Cancer, vol. 114, no. 11, pp. 1235–1242 . https://doi.org/10.1038/bjc.2016.91
Background:WFDC1/Prostate stromal 20 (ps20) is a small secreted protein highly expressed within the prostate stroma. WFDC1/ps20 expression is frequently downregulated or lost in prostate cancer (PCa) and ps20 has demonstrated growth-suppressive funct