Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shubha Dighe"'
Autor:
T. Tiffany Wang, Jun Yang, Shubha Dighe, Matthew W. Schmachtenberg, Nathan T. Leigh, Emily Farber, Suna Onengut-Gumuscu, David J. Feith, Aakrosh Ratan, Thomas P. Loughran, Thomas L. Olson
Publikováno v:
Cancers, Vol 12, Iss 1, p 126 (2020)
Large granular lymphocyte (LGL) leukemia arises spontaneously in elderly Fischer (F344) rats. This rodent model has been shown to emulate many aspects of the natural killer (NK) variant of human LGL leukemia. Previous transplantation of leukemic mate
Externí odkaz:
https://doaj.org/article/affba29aad0143aba8fad0a7f8e317b9
Autor:
Yong Zhang, Jun Yang, Shubha Dighe, Thomas A. Waldmann, Nazli Azimi, Sigrid Dubois, Yutaka Tagaya, Thomas P. Loughran, Meili Zhang, T. Tiffany Wang, Cait E. Hamele, David J. Feith, Kevin C. Conlon, Thomas L. Olson
Publikováno v:
Leukemia. 33:1243-1255
Interleukin-15 (IL-15) and IL-2 drive T-cell malignancies including T-cell large granular lymphocyte leukemia (T-LGLL) and HTLV-1 driven adult T-cell leukemia (ATL). Both cytokines share common γ-chain receptors and downstream signaling pathways. T-
Autor:
Matthew W. Schmachtenberg, T. Tiffany Wang, Suna Onengut-Gumuscu, David J. Feith, Thomas L. Olson, Jun Yang, Emily Farber, Thomas P. Loughran, Aakrosh Ratan, Shubha Dighe, Nathan T. Leigh
Publikováno v:
Cancers, Vol 12, Iss 1, p 126 (2020)
Cancers
Volume 12
Issue 1
Cancers
Volume 12
Issue 1
Large granular lymphocyte (LGL) leukemia arises spontaneously in elderly Fischer (F344) rats. This rodent model has been shown to emulate many aspects of the natural killer (NK) variant of human LGL leukemia. Previous transplantation of leukemic mate
Autor:
Jun Yang, Thomas L. Olson, Thomas P. Loughran, David J. Feith, Shubha Dighe, Cait E. Hamele, Francis R LeBlanc
Large granular lymphocyte (LGL) leukemia results from clonal expansion of CD3(+) cytotoxic T lymphocytes or CD3(−) natural killer (NK) cells. Chronic antigen stimulation is postulated to promote long-term survival of LGL leukemia cells through cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfd80c500df5a8c4449ab7e74b63907
https://europepmc.org/articles/PMC6014359/
https://europepmc.org/articles/PMC6014359/
Autor:
T Tiffany, Wang, Jun, Yang, Yong, Zhang, Meili, Zhang, Sigrid, Dubois, Kevin C, Conlon, Yutaka, Tagaya, Cait E, Hamele, Shubha, Dighe, Thomas L, Olson, David J, Feith, Nazli, Azimi, Thomas A, Waldmann, Thomas P, Loughran
Publikováno v:
Leukemia. 33(5)
Interleukin-15 (IL-15) and IL-2 drive T-cell malignancies including T-cell large granular lymphocyte leukemia (T-LGLL) and HTLV-1 driven adult T-cell leukemia (ATL). Both cytokines share common γ-chain receptors and downstream signaling pathways. T-
Autor:
Jesper Johansen, Giselle Duamel, Shubha Dighe, Christopher T. Beh, Gabriel Alfaro, Keith G. Kozminski
Publikováno v:
Traffic. 12:1521-1536
Oxysterol-binding protein (OSBP)-related protein Kes1/ Osh4p is implicated in nonvesicular sterol transfer between membranes in Saccharomyces cerevisiae. However, we found that Osh4p associated with exocytic vesicles that move from the mother cell in
Autor:
Giselle Duamel, Anant K. Menon, Christopher T. Beh, Michael C. Kersting, Keith G. Kozminski, David P. Sullivan, Gabriel Alfaro, Shubha Dighe
Publikováno v:
Molecular and Cellular Biochemistry. 326:9-13
Oxysterol-binding protein (OSBP) and OSBP-related proteins (ORPs) are a conserved family of soluble cytoplasmic proteins that can bind sterols, translocate between membrane compartments, and affect sterol trafficking. These properties make ORPs attra
Autor:
Shubha Dighe, Keith G. Kozminski
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99494 (2014)
PLoS ONE
PLoS ONE
The activation and localization of the Rho-family GTPase Cdc42p at one pole of a cell is necessary for maintaining an axis of polarized growth in many animal and fungal cells. How the asymmetric distribution of this key regulator of polarized morphog
Autor:
David J. Feith, Thomas P. Loughran, Susan B. Nyland, Jun Yang, Francis R Leblanc, Shubha Dighe
Publikováno v:
Blood. 128:2762-2762
Large granular lymphocyte (LGL) leukemia results from clonal expansion of CD3+ cytotoxic T-lymphocytes (CTL) or CD3-natural killer (NK) cells. Chronic antigen stimulation promotes long-term survival of LGL leukemia cells through constitutive activati
Autor:
Feven Tameire, Matthew Ryder, Stanley Fields, Marissa Vignali, Shubha Dighe, Kimberly M Yasutis, Keith G. Kozminski
Publikováno v:
Molecular Biology of the Cell
A C-terminal region in Zds2p (ZH4) is required for regulation of Swe1p-dependent polarized cell growth and this region is necessary and sufficient for interaction with protein phosphatase 2A regulatory subunit, Cdc55p. Our results indicate that the Z