Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shubha, Anantha"'
Autor:
Oleg V. Kurnasov, Vasiliy N. Goral, Shubha Anantha, Svetlana Gerdes, Andrei L. Osterman, Tadhg P. Begley, Keri L. Colabroy
Publikováno v:
Chemistry & Biology. 10(12):1195-1204
Previous studies have demonstrated two different biosynthetic pathways to quinolinate, the universal de novo precursor to the pyridine ring of NAD. In prokaryotes, quinolinate is formed from aspartate and dihydroxyacetone phosphate; in eukaryotes, it
Autor:
Konstantin Shatalin, Axel Bernal, Michael A. Farrell, Matthew D. Daugherty, Andrei L. Osterman, Faika Mseeh, Shamim A. K. Chowdhury, Shubha Anantha, Mark V. Baev, John W. Campbell, Oleg V. Kurnasov, Michael Fonstein, Boris Polanuyer, Mark D'Souza, Michael D. Scholle, Svetlana Gerdes
Publikováno v:
Journal of Bacteriology. 184:4555-4572
Novel drug targets are required in order to design new defenses against antibiotic-resistant pathogens. Comparative genomics provides new opportunities for finding optimal targets among previously unexplored cellular functions, based on an understand
Autor:
Ahmed Lasfar, Walid Abushahba, Bin Tian, Shubha Anantha, Faruk G. Sheikh, Anita Lewis-Antes, Kenneth R. Reuhl, Sergei V. Kotenko, Sergey V. Smirnov, Raymond P. Donnelly, Elizabeth Raveche, Harold L. Dickensheets
Publikováno v:
Cancer research. 66(8)
Recently discovered type III IFNs (IFN-lambda) exert their antiviral and immunomodulatory activities through a unique receptor complex composed of IFN-lambdaR1 and interleukin-10 receptor 2. To further study type III IFNs, we cloned and characterized
Autor:
Sergei V. Kotenko, Shubha Anantha, Nital K. Shah, Harold Dickensheets, Vitaliy V. Baurin, Jean-Christophe Renauld, Faruk Sheikh, Alexander Zdanov, Raymond P. Donnelly, Sergey V. Smirnov, Anita Lewis-Antes, Laure Dumoutier
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), Vol. 172, no. 4, p. 2006-2010 (2004)
The receptor for IL-26 (AK155), a cytokine of the IL-10 family, has not previously been defined. We demonstrate that the active receptor complex for IL-26 is a heterodimer composed of two receptor proteins: IL-20R1 and IL-10R2. Signaling through the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d9e678fbc8b501675002df9e6c29d9
https://hdl.handle.net/2078.1/83944
https://hdl.handle.net/2078.1/83944
Autor:
Oleg, Kurnasov, Vasiliy, Goral, Keri, Colabroy, Svetlana, Gerdes, Shubha, Anantha, Andrei, Osterman, Tadhg P, Begley
Publikováno v:
Chemistrybiology. 10(12)
Previous studies have demonstrated two different biosynthetic pathways to quinolinate, the universal de novo precursor to the pyridine ring of NAD. In prokaryotes, quinolinate is formed from aspartate and dihydroxyacetone phosphate; in eukaryotes, it