Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Shubbir, Ahmed"'
Autor:
Rahul Ahuja, Preeti Vishwakarma, Sneha Raj, Varun Kumar, Ritika Khatri, Bharat Lohiya, Shikha Saxena, Gurleen Kaur, Gagandeep Singh, Shailendra Asthana, Shubbir Ahmed, Sweety Samal
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTMiddle East respiratory syndrome coronavirus (MERS-CoV) is a lethal beta-coronavirus that emerged in 2012. The virus is part of the WHO blueprint priority list with a concerning fatality rate of 35%. Scientific efforts are ongoing for the dev
Externí odkaz:
https://doaj.org/article/4e44e7d9cd2b4a2bae31dfb3939ef7df
Autor:
Gazala Siddqui, Preeti Vishwakarma, Shikha Saxena, Varun Kumar, Sneh Bajpai, Amit Kumar, Satish Kumar, Ritika Khatri, Jaskaran Kaur, Sankar Bhattacharya, Shubbir Ahmed, Gulam Hussain Syed, Yashwant Kumar, Sweety Samal
Publikováno v:
Virus Research, Vol 341, Iss , Pp 199331- (2024)
Dengue virus infection in humans ranges from asymptomatic infection to severe infection, with ∼2.5 % overall disease fatality rate. Evidence of neurological manifestations is seen in the severe form of the disease, which might be due to the direct
Externí odkaz:
https://doaj.org/article/d5e30de1e58f4471927f65f2a30d836c
Autor:
Hilal Ahmad Parray, Naveen Narayanan, Sonal Garg, Zaigham Abbas Rizvi, Tripti Shrivastava, Sachin Kushwaha, Janmejay Singh, Praveenkumar Murugavelu, Anbalagan Anantharaj, Farha Mehdi, Nisha Raj, Shivam Singh, Jyotsna Dandotiya, Asha Lukose, Deepti Jamwal, Sandeep Kumar, Adarsh K Chiranjivi, Samridhi Dhyani, Nitesh Mishra, Sanjeev Kumar, Kamini Jakhar, Sudipta Sonar, Anil Kumar Panchal, Manas Ranjan Tripathy, Shirlie Roy Chowdhury, Shubbir Ahmed, Sweety Samal, Shailendra Mani, Sankar Bhattacharyya, Supratik Das, Subrata Sinha, Kalpana Luthra, Gaurav Batra, Devinder Sehgal, Guruprasad R Medigeshi, Chandresh Sharma, Amit Awasthi, Pramod Kumar Garg, Deepak T Nair, Rajesh Kumar
Publikováno v:
PLoS Pathogens, Vol 18, Iss 12, p e1010994 (2022)
The emergence of new variants of SARS-CoV-2 necessitates unremitting efforts to discover novel therapeutic monoclonal antibodies (mAbs). Here, we report an extremely potent mAb named P4A2 that can neutralize all the circulating variants of concern (V
Externí odkaz:
https://doaj.org/article/3ba087963a9548d5823331f44d97566f
Autor:
Nazia Ahmad, Sanmati Dugad, Varsha Chauhan, Shubbir Ahmed, Kunal Sharma, Sangita Kachhap, Rana Zaidi, William R Bishai, Gyanu Lamichhane, Pankaj Kumar
Publikováno v:
eLife, Vol 11 (2022)
L,D-transpeptidase function predominates in atypical 3 → 3 transpeptide networking of peptidoglycan (PG) layer in Mycobacterium tuberculosis. Prior studies of L,D-transpeptidases have identified only the catalytic site that binds to peptide moiety
Externí odkaz:
https://doaj.org/article/c3aa0ba8554541dba66cbb345a176ce6
Autor:
Sneha Raj, Preeti Vishwakarma, Shikha Saxena, Varun Kumar, Ritika Khatri, Amit Kumar, Mrityunjay Singh, Surbhi Mishra, Shailendra Asthana, Shubbir Ahmed, Sweety Samal
Publikováno v:
Vaccines, Vol 11, Iss 4, p 780 (2023)
Immunogens mimicking the native-like structure of surface-exposed viral antigens are considered promising vaccine candidates. Influenza viruses are important zoonotic respiratory viruses with high pandemic potential. Recombinant soluble hemagglutinin
Externí odkaz:
https://doaj.org/article/59841b706470484fae89e886c89a81c8
Autor:
Rajesh Kumar, Suprit Deshpande, Leigh M Sewall, Gabriel Ozorowski, Christopher A Cottrell, Wen-Hsin Lee, Lauren G Holden, Sara T Richey, Antra Singh Chandrawacar, Kanika Dhiman, Ashish, Vivek Kumar, Shubbir Ahmed, Nitin Hingankar, Naresh Kumar, Kailapuri G Murugavel, Aylur K Srikrishnan, Devin Sok, Andrew B Ward, Jayanta Bhattacharya
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1008977 (2021)
Evaluating the structure-function relationship of viral envelope (Env) evolution and the development of broadly cross-neutralizing antibodies (bnAbs) in natural infection can inform rational immunogen design. In the present study, we examined the mag
Externí odkaz:
https://doaj.org/article/5c0bde4098d240bfabd6e084c96ccc53
Autor:
Preeti Vishwakarma, Naveen Yadav, Zaigham Abbas Rizvi, Naseem Ahmed Khan, Adarsh Kumar Chiranjivi, Shailendra Mani, Manish Bansal, Prabhanjan Dwivedi, Tripti Shrivastava, Rajesh Kumar, Amit Awasthi, Shubbir Ahmed, Sweety Samal
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) initiates infection by attachment of the surface-exposed spike glycoprotein to the host cell receptors. The spike glycoprotein (S) is a promising target for inducing immune responses and pr
Externí odkaz:
https://doaj.org/article/d57fcbb25acf487cb08fa207a9172f08
Publikováno v:
Therapeutic Advances in Vaccines and Immunotherapy, Vol 8 (2020)
The enormous diversity of HIV-1 is a significant impediment in selecting envelopes (Envs) that can be suitable for designing vaccine immunogens. While tremendous progress has been made in developing soluble, trimeric, native-like Env proteins, those
Externí odkaz:
https://doaj.org/article/7f5276a3a5b045ba87fcbfb035816ea3
Autor:
Ritika Khatri, Gazala Siddqui, Srikanth Sadhu, Vikas Maithil, Preeti Vishwakarma, Bharat Lohiya, Abhishek Goswami, Shubbir Ahmed, Amit Awasthi, Sweety Samal
Publikováno v:
Medical Microbiology and Immunology. 212:103-122
The SARS-CoV-2 virus has been rapidly evolving over the time and the genetic variation has led to the generation of Variants of Concerns (VoC), which have shown increased fitness. These VoC viruses contain the key mutations in the spike protein which
Autor:
Adarsh Kumar, Chiranjivi, Dilip, Kumar, Rajesh, Kumar, Hilal Ahmad, Parray, Shubbir, Ahmed, Chandra Sekhar, Kumar, Tripti, Shrivastava, Manidipa, Banerjee, B V Venkataram, Prasad, Supratik, Das
Publikováno v:
International Journal of Biological Macromolecules. 217:19-26
Dengue virus is transmitted by Aedes mosquitoes and dengue is endemic in many regions of the world. Severe dengue results in complications that may lead to death. Although some vaccine candidates are in clinical trials and one vaccine Dengvaxia, with