Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Shuanhu Zhou"'
Autor:
Qiting He, Ruixi Qin, Julie Glowacki, Shuanhu Zhou, Jie Shi, Shaoyi Wang, Yuan Gao, Lei Cheng
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Vitamin D is important for the mineralization of bones by stimulating osteoblast differentiation of bone marrow mesenchymal stem cells (BMMSCs). BMMSCs are a target of vitamin D action, and the metabolism of 25(OH)D3 to biological
Externí odkaz:
https://doaj.org/article/899e579bf8db41f4ad393829acba5e82
Autor:
Hongmei Du, Zijun Huo, Yanchun Chen, Zhenhan Zhao, Fandi Meng, Xuemei Wang, Shiyue Liu, Haoyun Zhang, Fenghua Zhou, Jinmeng Liu, Lingyun Zhang, Shuanhu Zhou, Yingjun Guan, Xin Wang
Publikováno v:
Cells, Vol 12, Iss 6, p 971 (2023)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that results in the loss of motor function in the central nervous system (CNS) and ultimately death. The mechanisms underlying ALS pathogenesis have not yet been fully elu
Externí odkaz:
https://doaj.org/article/79098bfcb61d48a9a549f0438795f6d0
Autor:
Dongyang Qian, Hui Zhou, Pan Fan, Tao Yu, Anish Patel, Morgan O’Brien, Zhe Wang, Shiguang Lu, Guoqiang Tong, Yimin Shan, Lei Wang, Yuan Gao, Yuan Xiong, Lily Zhang, Xin Wang, Yuancai Liu, Shuanhu Zhou
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Traditional Chinese medicine (TCM) has been practiced in the treatment of bone diseases and alcoholism. Chronic excessive alcohol use results in alcohol-induced bone diseases, including osteopenia and osteoporosis, which increases fracture risk, defi
Externí odkaz:
https://doaj.org/article/81237362a21b43c8b506e1269898570e
Autor:
Zunguo Hu, Shuang Wen, Zijun Huo, Qing Wang, Jiantao Zhao, Zihao Wang, Yanchun Chen, Lingyun Zhang, Fenghua Zhou, Zhangyu Guo, Huancai Liu, Shuanhu Zhou
Publikováno v:
Cells, Vol 11, Iss 21, p 3507 (2022)
Osteosarcoma (OS) is a highly malignant tumor occurring in bone tissue with a high propensity to metastasize, and its underlying mechanisms remain largely elusive. The OS prognosis is poor, and improving the survival of OS patients remains a challeng
Externí odkaz:
https://doaj.org/article/b5449776fd0e40339c65762555349e70
Autor:
Jiantao Zhao, Xuemei Wang, Zijun Huo, Yanchun Chen, Jinmeng Liu, Zhenhan Zhao, Fandi Meng, Qi Su, Weiwei Bao, Lingyun Zhang, Shuang Wen, Xin Wang, Huancai Liu, Shuanhu Zhou
Publikováno v:
Cells, Vol 11, Iss 13, p 2049 (2022)
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and highly fatal neurodegenerative disease. Although the pathogenesis of ALS remains unclear, increasing evidence suggests that a key contributing factor is mitochondrial dysfunction. Mitoc
Externí odkaz:
https://doaj.org/article/61afb7bb2a734f0f97d5cadb6da07a85
Autor:
Taifeng Zhou, Bo Gao, Yi Fan, Yuchen Liu, Shuhao Feng, Qian Cong, Xiaolei Zhang, Yaxing Zhou, Prem S Yadav, Jiachen Lin, Nan Wu, Liang Zhao, Dongsheng Huang, Shuanhu Zhou, Peiqiang Su, Yingzi Yang
Publikováno v:
eLife, Vol 9 (2020)
Mechanical forces are fundamental regulators of cell behaviors. However, molecular regulation of mechanotransduction remain poorly understood. Here, we identified the mechanosensitive channels Piezo1 and Piezo2 as key force sensors required for bone
Externí odkaz:
https://doaj.org/article/10de8380c66e4cb3aa25c1b6927e92c5
Autor:
Jinmeng Liu, Fenghua Zhou, Yingjun Guan, Fandi Meng, Zhenhan Zhao, Qi Su, Weiwei Bao, Xuemei Wang, Jiantao Zhao, Zijun Huo, Lingyun Zhang, Shuanhu Zhou, Yanchun Chen, Xin Wang
Publikováno v:
Cells, Vol 11, Iss 3, p 572 (2022)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects upper and lower motor neurons. As there is no effective treatment for ALS, it is particularly important to screen key gene therapy targets. The identifications of microRN
Externí odkaz:
https://doaj.org/article/fee28e9d6e1248e18b9a92ae7a9c5189
Autor:
Xin Jiang, Yingjun Guan, Zhenhan Zhao, Fandi Meng, Xuemei Wang, Xueshuai Gao, Jinmeng Liu, Yanchun Chen, Fenghua Zhou, Shuanhu Zhou, Xin Wang
Publikováno v:
Cells, Vol 10, Iss 4, p 839 (2021)
The WNT signaling pathway plays an important role in the physiological and pathophysiological processes of the central nervous system and the neurodegenerative disease amyotrophic lateral sclerosis (ALS). We reviewed the literature pertinent to WNT/
Externí odkaz:
https://doaj.org/article/45d83d780bb0450a990ad2c3b3f858c5
Autor:
Lushuang Xie, Qiaofeng Wu, Li, Kelin, Khan, Mohammed A. S., Zhang, Andrew, Sinha, Bharati, Sihui Li, Chang, Sulie L., Brody, David L., Grinstaff, Mark W., Shuanhu Zhou, Alterovitz, Gil, Pinghua Liu, Xin Wang
Publikováno v:
Aging & Disease; Oct2024, Vol. 15 Issue 5, p2168-2190, 23p
Autor:
Shuanhu Zhou, Qiting He, Shaoyi Wang, Julie Glowacki, Yuan Gao, Ruixi Qin, Jie Shi, Lei Cheng
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Background Vitamin D is important for the mineralization of bones by stimulating osteoblast differentiation of bone marrow mesenchymal stem cells (BMMSCs). BMMSCs are a target of vitamin D action, and the metabolism of 25(OH)D3 to biologically active