Zobrazeno 1 - 10 of 43 pro vyhledávání: '"Shuangyou Liu"'
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Akademický článek
Humanized CD19 CAR-T cells in relapsed/refractory B-ALL patients who relapsed after or failed murine CD19 CAR-T therapy
Autor: Lihong An, Yuehui Lin, Biping Deng, Zhichao Yin, Defeng Zhao, Zhuojun Ling, Tong Wu, Yongqiang Zhao, Alex H. Chang, Chunrong Tong, Shuangyou Liu
Publikováno v: BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background For CD19-positive relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL) after treatment with murine CD19 (mCD19) CAR-T, the reinfusion of mCD19 CAR-T cells may be ineffective due to anti-mouse single-chain variable f
Externí odkaz: https://doaj.org/article/a2fdeb5fa2514754859629de837f704e
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3
Akademický článek
Peripheral leukemia burden at time of apheresis negatively affects the clinical efficacy of CART19 in refractory or relapsed B-ALL
Autor: Biping Deng, Jing Pan, Zhaoli Liu, Shuangyou Liu, Yunlong Chen, Xiaomin Qu, Yu'e Zhang, Yuehui Lin, Yanlei Zhang, Xinjian Yu, Zhongxin Zhang, Xuansha Niu, Rong Luan, Ming Ma, Xiaomei Li, Tingting Liu, Xi'ai Wu, Huan Niu, Alex H. Chang, Chunrong Tong
Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 633-643 (2021)
Our previous clinical study achieved complete remission (CR) rates of >90% following chimeric antigen receptor T cells targeting CD19 (CART19) treatment of refractory/relapsed B cell acute lymphoblastic leukemia (r/r B-ALL); however, the influence of
Externí odkaz: https://doaj.org/article/8a5d1e95aae845aaab269d3ee1c2bab7
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4
Akademický článek
CAR‐T therapy as a consolidation in remission B‐ALL patients with poor prognosis
Autor: Zhichao Yin, Yuehui Lin, Dan Liu, Chunrong Tong, Shuangyou Liu
Publikováno v: Cancer Reports, Vol 5, Iss 10, Pp n/a-n/a (2022)
Abstract Background To date, almost all studies regarding chimeric antigen receptor (CAR)‐T cell therapy for B‐cell acute lymphoblastic leukemia (B‐ALL) were performed in refractory/relapsed (r/r) or minimal residual disease‐positive patients
Externí odkaz: https://doaj.org/article/ec9307a0844b4a15b4b88a166f1500d5
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5
Akademický článek
Berberine Induces Apoptosis in p53-Null Leukemia Cells by Down-Regulating XIAP at the Post-Transcriptional Level
Autor: Jian Liu, Xiaoling Zhang, Aiguo Liu, Shuangyou Liu, Liuqing Zhang, Bei Wu, Qun Hu
Publikováno v: Cellular Physiology and Biochemistry, Vol 32, Iss 5, Pp 1213-1224 (2013)
Background: Berberine exerts anticancer activities both in vitro and in vivo through different mechanisms. However, the underlying molecular mechanisms of berberine induced p53-independent apoptosis remain unclear. Methods: The p53-null leukemia cell
Externí odkaz: https://doaj.org/article/2557d3e8f9bc41f381584fea84317377
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6
CD7 CAR-T therapy for an AML patient with CD7 expression
Autor: Lihong An, Ruifeng Hou, Huanhuan Guan, Zhihui Li, Tong Wu, Shuangyou Liu
Publikováno v: Hematology and Oncology Discovery. 1
To date, no ideal CAR-T product is available for treating acute myeloid leukemia (AML). Recently, CD7 CAR-T therapy has shown promising efficiency in treating T-cell acute lymphoblastic leukemia. Because the CD7 antigen is also expressed on the myelo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36e3b9a7a3db090df2406eb1afe7d725
https://doi.org/10.15212/hod-2022-0007
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