Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Shuanghu Liu"'
Autor:
Yucel Aydin, Milad Chedid, Srinivas Chava, Donkita Danielle Williams, Shuanghu Liu, Curt H. Hagedorn, Suchitra Sumitran-Holgersson, Krzysztof Reiss, Krzysztof Moroz, Hua Lu, Luis A. Balart, Srikanta Dash
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/037008dbf48c417497970994ce74207f
Autor:
Yucel Aydin, Milad Chedid, Srinivas Chava, Donkita Danielle Williams, Shuanghu Liu, Curt H. Hagedorn, Suchitra Sumitran-Holgersson, Krzysztof Reiss, Krzysztof Moroz, Hua Lu, Luis A. Balart, Srikanta Dash
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract The mechanism of how chronic hepatitis C virus (HCV) infection leads to such a high rate of hepatocellular carcinoma (HCC) is unknown. We found that the PERK axis of endoplasmic reticulum (ER) stress elicited prominent nuclear translocation
Externí odkaz:
https://doaj.org/article/1c273bda27a2435b98c2b3064a561524
Autor:
Bret S. E. Heale, Shuanghu Liu, Don A. Delker, Neven Papic, Christopher I. Maxwell, Curt H. Hagedorn
Publikováno v:
Viruses, Vol 4, Iss 4, Pp 581-612 (2012)
We describe the first report of RNA sequencing of 5' capped (Pol II) RNAs isolated from acutely hepatitis C virus (HCV) infected Huh 7.5 cells that provides a general approach to identifying differentially expressed annotated and unannotated genes th
Externí odkaz:
https://doaj.org/article/21c063c461194364902b8cd85a1566aa
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131358 (2015)
Chronic infection with the hepatitis C virus (HCV) is a cause of cirrhosis and hepatocellular carcinoma worldwide. Although antiviral therapy has dramatically improved recently, a number of patients remain untreated and some do not clear infection wi
Externí odkaz:
https://doaj.org/article/fa09d8d413ea423d979c22541dea38ec
Publikováno v:
PLoS ONE, Vol 8, Iss 5 (2013)
Externí odkaz:
https://doaj.org/article/c6679de665cc49dda20dc13992f3fcef
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44965 (2012)
The unique properties of the hepatitis C virus (HCV) JFH1 isolate have made it possible to produce and study HCV in an infectious cell culture system. However, relatively low virus titers restrict some of the uses of this system and preparing infecti
Externí odkaz:
https://doaj.org/article/b8e4ed116dfe4c0fb899b5efd588db0c
Publikováno v:
International Journal of Biological Sciences
Infectious HCV carrying reporter genes have further applications in understanding the HCV life cycle including replication, viral assembly and release. In this study, a full-length 3039bp LacZ gene was inserted into the derivative of JFH1-AM120 to de
Autor:
Milad Chedid, Srinivas Chava, Donkita Danielle Williams, Krzysztof Moroz, Suchitra Sumitran-Holgersson, Krzysztof Reiss, Yucel Aydin, Srikanta Dash, Luis A. Balart, Hua Lu, Shuanghu Liu, Curt H. Hagedorn
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Scientific Reports
Scientific Reports
The mechanism of how chronic hepatitis C virus (HCV) infection leads to such a high rate of hepatocellular carcinoma (HCC) is unknown. We found that the PERK axis of endoplasmic reticulum (ER) stress elicited prominent nuclear translocation of Nrf2 i
Autor:
Shuanghu Liu, Yueh Ming Loo, Joseph Pangallo, Chrissie Lim, Curt H. Hagedorn, Michael Gale, Ram Savan, Alison M. Kell, Abigail Jarret, Mee Ae Hong, Johannes Schwerk
Publikováno v:
The Journal of Experimental Medicine
Hong et al. show that IFNλ4 exhibits similar antiviral activity to IFNλ3. Humans deploy several mechanisms to limit expression of functional IFNλ4 through noncoding splice variants and nonfunctional protein isoforms.
Interferon (IFN) lambdas
Interferon (IFN) lambdas
Autor:
Hua Lu, Krzysztof Reiss, Donkita Danielle Williams, Shuanghu Liu, Milad Chedid, Luis A. Balart, Suchitra Sumitran-Holgersson, Srikanta Dash, Srinivas Chava, Yucel Aydin, Krzysztof Moroz, Curt H. Hagedorn
Publikováno v:
Scientific Reports. 7
The mechanism of how chronic hepatitis C virus (HCV) infection leads to such a high rate of hepatocellular carcinoma (HCC) is unknown. We found that the PERK axis of endoplasmic reticulum (ER) stress elicited prominent nuclear translocation of Nrf2 i