Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Shuangfei Ni"'
Autor:
Chenhao Shi, Yonggang Fan, Xiusheng Huang, Mingzhe Fan, Lantian Zhao, Huafeng Zhang, Shuangfei Ni
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Low back pain (LBP) is largely attributed to intervertebral disc degeneration (IVDD), of which the endplate changes are an important component. However, the alterations in cell fate and properties within the endplates during degeneration rem
Externí odkaz:
https://doaj.org/article/fa4e03300ed24adea12a3c6ab5665bed
Autor:
Yonggang Fan, Weixin Zhang, Xiusheng Huang, Mingzhe Fan, Chenhao Shi, Lantian Zhao, Guofu Pi, Huafeng Zhang, Shuangfei Ni
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Endplate sclerosis is a notable aspect of spine degeneration or aging, but the mechanisms remain unclear. Here, we report that senescent macrophages accumulate in the sclerotic endplates of lumbar spine instability (LSI) or aging male mouse
Externí odkaz:
https://doaj.org/article/ad65108ea9b34cd5808be66993bc1250
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The m6A methylation is reported to function in multiple physiological and pathological processes. However, the functional relevance of m6A modification to post-spinal cord injured (SCI) damage is not yet clear. In the present study, methylated RNA im
Externí odkaz:
https://doaj.org/article/507c7a8c553640df9974bc6c108a991f
Autor:
Ruoxian Deng, Changwei Li, Xiao Wang, Leilei Chang, Shuangfei Ni, Weixin Zhang, Peng Xue, Dayu Pan, Mei Wan, Lianfu Deng, Xu Cao
Publikováno v:
Advanced Science, Vol 9, Iss 3, Pp n/a-n/a (2022)
Abstract Mechanical force regulates bone density, modeling, and homeostasis. Substantial periosteal bone formation is generated by external mechanical stimuli, yet its mechanism is poorly understood. Here, it is shown that myeloid‐lineage cells dif
Externí odkaz:
https://doaj.org/article/cfcd11a45d724f4b82ea0aa9b5fbc552
Autor:
Shuangfei Ni, Zemin Ling, Xiao Wang, Yong Cao, Tianding Wu, Ruoxian Deng, Janet L. Crane, Richard Skolasky, Shadpour Demehri, Gehua Zhen, Amit Jain, Panfeng Wu, Dayu Pan, Bo Hu, Xiao Lyu, Yusheng Li, Hao Chen, Huabin Qi, Yun Guan, Xinzhong Dong, Mei Wan, Xuenong Zou, Hongbin Lu, Jianzhong Hu, Xu Cao
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Spinal pain is a major clinical problem. Here the authors show that osteoclasts create porous area of endplates of the vertebrae and sensory innervation of porous endplates by Netrin-1 release from osteoclasts mediates PGE2-induced spinal hypersensit
Externí odkaz:
https://doaj.org/article/98071ec5c6bf43b7abff3310ff804c58
Autor:
Hao Chen, Bo Hu, Xiao Lv, Shouan Zhu, Gehua Zhen, Mei Wan, Amit Jain, Bo Gao, Yu Chai, Mi Yang, Xiao Wang, Ruoxian Deng, Lei Wang, Yong Cao, Shuangfei Ni, Shen Liu, Wen Yuan, Huajiang Chen, Xinzhong Dong, Yun Guan, Huilin Yang, Xu Cao
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Bone is innervated, and its turnover is affected by sympathetic nerve activity. Here, the authors show that prostaglandin E2, secreted by osteoblasts, activates the EP4 receptor on sensory nerves, inhibiting sympathetic nerve activity and modulating
Externí odkaz:
https://doaj.org/article/8d431045fb1444baaa1a6a79863f3b83
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Acute spinal cord injury (ASCI) is a severe traumatic disease of the central nervous system, the underlying mechanism of which is unclear. This study was intended to study the role of EZH2 and miR-146a-5p/HIF-1α in inflammation and glycolysis after
Externí odkaz:
https://doaj.org/article/ea2f25711c5c4f53a03263ba5bbe8795
Association of Sedentary Behavior With Anxiety, Depression, and Suicide Ideation in College Students
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Objectives: To investigate the association of sedentary behavior with anxiety, depression, and suicide ideation in multi-centered college students in China.Methods: This was a cross-sectional study of the first-year college student population. The st
Externí odkaz:
https://doaj.org/article/4b5ddc938a794d05b9aef2884adcfab9
Publikováno v:
Acta Orthopaedica et Traumatologica Turcica, Vol 52, Iss 4, Pp 277-282 (2018)
Objective: The aim of this study was to evaluate the clinical outcomes of one-stage posterior debridement, interbody fusion, and instrumentation, combined with irrigation and drainage, for treating lumbar spondylodiscitis. Methods: The study included
Externí odkaz:
https://doaj.org/article/56604d3817f340beb5aec23c84a1c68d
Publikováno v:
Energies, Vol 13, Iss 17, p 4490 (2020)
With the aim to solve the problem related to the power chattering and anti-disturbance performance of a photovoltaic (PV) inverter in master–slave-organized islanded microgrid, an anti-disturbance finite-time adaptive sliding mode backstepping (DFA
Externí odkaz:
https://doaj.org/article/54ae9fed53c54e6dab1c43e98b6e8ace