Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Shuangbing Xu"'
Autor:
Yunshang Chen, Xue Feng, Zilong Wu, Yongqiang Yang, Xinrui Rao, Rui Meng, Sheng Zhang, Xiaorong Dong, Shuangbing Xu, Gang Wu, Xiaohua Jie
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-18 (2024)
Abstract Background Radioresistance is a key clinical constraint on the efficacy of radiotherapy in lung cancer patients. REV1 DNA directed polymerase (REV1) plays an important role in repairing DNA damage and maintaining genomic stability. However,
Externí odkaz:
https://doaj.org/article/9a17e0830ff24a45930d6874330c15a4
Autor:
Zixuan Li, Huichan Xue, Jinsong Li, Zhikun Zheng, Zhiwei Liu, Xiaorong Dong, Hongbo Wang, Jing Chen, Shuangbing Xu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Background The evasion of the immune response by tumor cells through programmed death-ligand 1 (PD-L1) has been identified as a factor contributing to resistance to radioimmunotherapy in lung cancer patients. However, the precise molecular m
Externí odkaz:
https://doaj.org/article/1a8bcd84e3f546e3aec8b5b1a9609f07
Autor:
Yunshang Chen, Yun Zhou, Xue Feng, Zilong Wu, Yongqiang Yang, Xinrui Rao, Rui Zhou, Rui Meng, Xiaorong Dong, Shuangbing Xu, Sheng Zhang, Gang Wu, Xiaohua Jie
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Radioresistance is a major constraint on the efficacy of lung cancer radiotherapy, but its mechanism has not been fully elucidated. Here, we found that FBXO22 was aberrantly highly expressed in lung cancer and that FBXO22 knockdown increased
Externí odkaz:
https://doaj.org/article/24cc7d0f86ba4eb685bae0bb02f901b9
Autor:
Yanwei Lu, Jia Ma, Yan Li, Jing Huang, Sheng Zhang, Zhongyuan Yin, Jinghua Ren, Kai Huang, Gang Wu, Kunyu Yang, Shuangbing Xu
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/4587335d9b1548aab25e6e70fec46cdb
Autor:
Zhen Zeng, Zixuan Li, Jun Xue, Huichan Xue, Zhiwei Liu, Wenxuan Zhang, Hongli Liu, Shuangbing Xu
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract KDM4C, which is a histone lysine demethylase, has been proposed to participate in the malignant transformation and progression of several types of cancer. However, its roles in hepatocellular carcinoma (HCC) remain poorly understood. Here, w
Externí odkaz:
https://doaj.org/article/4eeefbb821004445bb3cfa3cc66e16c6
Autor:
Qiwen Li, Li Ma, Bo Qiu, Yuzhi Wen, Wenhua Liang, Wanming Hu, Naibin Chen, Tian Zhang, Shuangbing Xu, Lingjuan Chen, Minzhang Guo, Yi Zhao, Songran Liu, Jinyu Guo, Junye Wang, Siyu Wang, Xin Wang, Qingsong Pang, Hao Long, Hui Liu
Publikováno v:
Current Oncology, Vol 28, Iss 2, Pp 1424-1436 (2021)
Background: Recent studies have demonstrated benefits from adjuvant tyrosine-kinase inhibitors (TKIs) compared with chemotherapy in non-small cell lung cancer. We launched a multi-center retrospective study to evaluate the efficacy and toxicity of ad
Externí odkaz:
https://doaj.org/article/21b7fcea66f2470d9451bdc59acd8175
Autor:
Tao Zhang, Jian Wang, Sheng Zhang, Xiaorong Dong, Gang Wu, Ye Zhao, Kunyu Yang, Xiaohua Jie, Yunshang Chen, Xijie Yang, Yingzhuo Xu, Rui Meng, Shuangbing Xu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/f58bb4b6e64544e28fe4d3af8e3817fe
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-13 (2020)
Abstract Background NEK2, a serine/threonine kinase involved in mitosis, has been found to function in chromosome instability, tumor progression and metastasis, but its role in cervical cancer radioresistance remains unknown. Methods We detected the
Externí odkaz:
https://doaj.org/article/a6a7f996d1ff4027b39cbb27bf764a39
Autor:
Jian Wang, Ruiguang Zhang, Zhenyu Lin, Sheng Zhang, Yaobing Chen, Jing Tang, Jiaxin Hong, Xiaoshu Zhou, Yan Zong, Yingzhuo Xu, Rui Meng, Shuangbing Xu, Li Liu, Tao Zhang, Kunyu Yang, Xiaorong Dong, Gang Wu
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-16 (2020)
Abstract Background The cyclin-dependent kinase 7 (CDK7) subunit of TFIIH regulates RNA polymerase-II-based transcription and promotes tumor progression. However, the mechanisms involved in CDK7-mediated immune evasion are unclear in non-small cell l
Externí odkaz:
https://doaj.org/article/9bc1f7df1fa640df86e7faae081890f6
Autor:
Jian Wang, Yingzhuo Xu, Xinrui Rao, Ruiguang Zhang, Jing Tang, Dan Zhang, Xiaohua Jie, Kuikui Zhu, Xu Wang, Yunhong Xu, Sheng Zhang, Xiaorong Dong, Tao Zhang, Kunyu Yang, Shuangbing Xu, Rui Meng, Gang Wu
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 1, Pp n/a-n/a (2022)
Background Chemoradiotherapy‐induced PD‐L1 upregulation leads to therapeutic resistance and treatment failure. The PD‐1/PD‐L1 blocking antibodies sensitize cancers to chemoradiotherapy by blocking extracellular PD‐1 and PD‐L1 binding with
Externí odkaz:
https://doaj.org/article/a93997b47b2d46afb44671beb873fc47