Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Shuang-xi Wang"'
Autor:
Zhao-yang Wang, Jie Cheng, Ying Wang, Hai-tao Yuan, Shao-jie Bi, Shuang-xi Wang, Ya-min Hou, Xu Zhang, Bo-han Xu, Ze-ying Wang, Yun Zhang, Wen-jian Jiang, Yu-guo Chen, Ming-xiang Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Imbalance of proinflammatory and anti-inflammatory responses plays a crucial role in the progression of abdominal aortic aneurysms. ILF3, a known modulator of the innate immune response, is involved in cardiovascular diseases. This study aim
Externí odkaz:
https://doaj.org/article/d90ef39fa4094894a63b2572af322af8
Autor:
Bin Li, Wen-Wu Bai, Tao Guo, Zhen-Yu Tang, Xue-Jiao Jing, Ti-Chao Shan, Sen Yin, Ying Li, Fu Wang, Mo-Li Zhu, Jun-Xiu Lu, Yong-Ping Bai, Bo Dong, Peng Li, Shuang-Xi Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Heart failure with preserved ejection fraction (HFpEF) is associated with endothelial dysfunction. We have previously reported that statins prevent endothelial dysfunction through inhibition of microRNA-133a (miR-133a). This study is to inve
Externí odkaz:
https://doaj.org/article/3c6c3428ca3c4a548436b2b8819e62d5
Autor:
Lei Li, Ya-juan Cui, Yu Liu, Hui-xin Li, Yu-dong Su, Sheng-nan Li, Lan-lan Wang, Yue-wen Zhao, Shuang-xi Wang, Feng Yan, Bo Dong
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-15 (2022)
Abstract Moderate autophagy can remove damaged proteins and organelles. In some inflammatory diseases, autophagy plays a protective role by inhibiting the NOD-like receptor family pyrin domain containing 3(NLRP3). (Pro)renin receptor (PRR, or ATP6AP2
Externí odkaz:
https://doaj.org/article/7b9c03c97e0942bba015e7a08e4e717d
Autor:
Tiantian Zhu, Minghui Li, Moli Zhu, Xu Liu, Keke Huang, Wenru Li, Shuang-Xi Wang, Yaling Yin, Peng Li
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 4, Pp 483-488 (2022)
Objective(s): Epigallocatechin-3-gallate (EGCG) has a good therapeutic effect on type 2 diabetes mellitus (T2DM). This work was designed to explore EGCG’s effectiveness in insulin resistance (IR) and pancreas islet β-cell function in a rat model o
Externí odkaz:
https://doaj.org/article/7db9e07204ba41bfb0f49f8f73b1da7d
Autor:
Yue Qiu, Xian-jun Xue, Geng Liu, Miao-miao Shen, Chun-yan Chao, Jie Zhang, Ya-qi Guo, Qian-qian Niu, Ya-nan Yu, Yu-ting Song, Huan-huan Wang, Shuang-xi Wang, Yu-jing Chen, Lin-hua Jiang, Peng Li, Ya-ling Yin
Publikováno v:
Chinese Medicine, Vol 16, Iss 1, Pp 1-13 (2021)
Abstract Background Vascular cognitive dysfunction in patients with vascular dementia (VD) is a kind of severe cognitive dysfunction syndrome caused by cerebrovascular diseases. At present, effective drugs to improve the cognitive function of VD pati
Externí odkaz:
https://doaj.org/article/da858a8994a24a6d82d9f2736a3c26ff
Autor:
Ya-Ling Yin, Yuan Chen, Feng Ren, Lu Wang, Mo-Li Zhu, Jun-Xiu Lu, Qian-Qian Wang, Cheng-Biao Lu, Chao Liu, Yong-Ping Bai, Shuang-Xi Wang, Jian-Zhi Wang, Peng Li
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102540- (2022)
Background: s: Hyperhomocysteinemia (HHcy) is one of risk factors for vascular cognitive impairment (VCI). GTP cyclohydrolase 1 (GCH1) deficiency is critical to oxidative stress in vascular dysfunction. The aim of this study was designed to examine w
Externí odkaz:
https://doaj.org/article/30e2b196d70a40f6ab159520d66a9f9c
Autor:
Peng Li, Mo-Li Zhu, Guo-Pin Pan, Jun-Xiu Lu, Fan-Rong Zhao, Xu Jian, Li-Ying Liu, Guang-Rui Wan, Yuan Chen, Song Ping, Shuang-Xi Wang, Chang-Ping Hu
Publikováno v:
Clinical and Experimental Hypertension, Vol 40, Iss 2, Pp 192-201 (2018)
Background: We have previously reported that the long-term exposure of organophosphorus induces vascular dementia (VD) in rats. As a coenzyme, vitamin B6 is mainly involved in the regulation of metabolisms. Whether vitamin B6 improves VD remains unkn
Externí odkaz:
https://doaj.org/article/da8fe1e968df4f839e949746ba4acc4c
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Backgrounds. VitB6 deficiency has been associated with a number of adverse health effects. However, the effects of VitB6 in metabolic syndrome are poorly understood. Methods. VitB6 (50 mg/kg/day) was given to Apoe-/- mice with hkdigh-fat diet (HFD) f
Externí odkaz:
https://doaj.org/article/d9161db4ca104afabbe739162afccc0e
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
It has been recognized that sodium hydrogen exchanger 1 (NHE1) is involved in the development of diabetic nephropathy. The role of NHE1 in kidney dysfunction induced by advanced glycation end products (AGEs) remains unknown. Renal damage was induced
Externí odkaz:
https://doaj.org/article/8ce6671500dc42fa8a03aa49425c53e6
Autor:
Bin Li, Rui Li, Chun Zhang, Hong-jun Bian, Fu Wang, Jie Xiao, Shan-wen Liu, Wei Yi, Ming-xiang Zhang, Shuang-xi Wang, Yun Zhang, Guo-hai Su, Xiao-ping Ji
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90096 (2014)
OBJECTIVES: MicroRNA-7 (miR-7) is highly connected to cancerous cell proliferation and metastasis. It is also involved in myocardial ischemia-reperfusion (I/R) injury and is upregulated in cardiomyocyte under simulated I/R (SI/R). We aimed to investi
Externí odkaz:
https://doaj.org/article/8eb15e12114a4118abf4f103bc9814c5