Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shuang‐Qi Gao"'
Publikováno v:
Brain and Behavior, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Introduction Repeated exposure to cocaine induces microglial activation. Cocaine exposure also induces a release of high mobility group box‐1 (HMGB1) from neurons into the extracellular space in the nucleus accumbens (NAc). HMGB1 is an imp
Externí odkaz:
https://doaj.org/article/4a29d66e5bf94adc9494029dce8da7cc
Autor:
Shuang-Qi Gao, Jun-Quan Chen, Hai-Yun Zhou, Lun Luo, Bao-Yu Zhang, Man-Ting Li, Hai-Yong He, Chuan Chen, Ying Guo
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106488- (2023)
Summary: Deficits in astrocyte function contribute to major depressive disorder (MDD) and suicide, but the therapeutic effect of directly reactivating astrocytes for depression remains unclear. Here, specific gains and losses of astrocytic cell funct
Externí odkaz:
https://doaj.org/article/d705283f2f6042c0a7713bf89a20ea0e
Autor:
Jun-Quan Chen, Shuang-Qi Gao, Lun Luo, Zong-Yuan Jiang, Chao-Feng Liang, Hai-Yong He, Ying Guo
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Traumatic brain injury (TBI) is a major global burden of health. As an accepted inflammatory mediator, high mobility group box 1 (HMGB1) is found to be effective in facilitating neurogenesis and axonal regeneration. SH3RF2 (also known as POSHER), an
Externí odkaz:
https://doaj.org/article/300b216924024969932e0a91d1e51068
Autor:
Hai-yun Zhou, Shuang-qi Gao, Yu-sheng Gong, Tong Lin, Shuai Tong, Wei Xiong, Chun-yang Shi, Wen-qing Wang, Jian-guo Fang
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 23, Iss , Pp 370-376 (2020)
Objectives: Herpes simplex virus 1 (HSV-1) is one of the most prevalent viruses in humans worldwide. Owing to limited therapeutic options mainly with acyclovir (ACV) and analogues and the emergence of ACV-resistant strains, new drugs with different m
Externí odkaz:
https://doaj.org/article/f3f7d8c9197a4ce391ba8950df684f66
Autor:
Shuang-qi Gao
Objectives The subsets of astrocytes in the brain have not been fully elucidated. Using bulk RNA sequencing, reactive astrocytes were divided into A1 versus A2. However, using single-cell RNAseq (ScRNAseq), astrocytes were divided into over two subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::793e3ee37d6d684524e89c3509df90eb
https://doi.org/10.21203/rs.3.rs-737027/v1
https://doi.org/10.21203/rs.3.rs-737027/v1
Autor:
Chunyang Shi, Wei Xiong, Wenqing Wang, Shuang-qi Gao, Hai-yun Zhou, Shuai Tong, Tong Lin, Yu-sheng Gong, Jianguo Fang
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 23, Iss, Pp 370-376 (2020)
Objectives Herpes simplex virus 1 (HSV-1) is one of the most prevalent viruses in humans worldwide. Owing to limited therapeutic options mainly with acyclovir (ACV) and analogues and the emergence of ACV-resistant strains, new drugs with different mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f588dc960c170fe1b75ab5d02142fd67
https://pubmed.ncbi.nlm.nih.gov/33161114
https://pubmed.ncbi.nlm.nih.gov/33161114
Autor:
Hui-Ling Zheng, Zhi-Fang Deng, Gang Zhao, Fang Wang, Yi Luo, Jun-Feng Xu, Ling-Qiang Zhu, Shuang-Qi Gao, Jia-Jing Lu, Yong-Hui Zhang, Hou-Hong Li, Deng-Zheng Zhang, Jian-Guo Chen
Publikováno v:
Cerebral Cortex. 29:1509-1519
β-Catenin has been implicated in major depressive disorder (MDD), which is associated with synaptic plasticity and dendritic arborization. MicroRNAs (miRNA) are small noncoding RNAs containing about 22 nucleotides and involved in a variety of physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a247ecb0f120e34b8ce2c58aa1379dc9
https://doi.org/10.1093/cercor/bhy047
https://doi.org/10.1093/cercor/bhy047
Autor:
Huan-Huan Zhao, Fang Wang, Jin-Gang He, Hai Zhang, Jun-Feng Xu, Hui-Ling Zheng, Zhuang-Li Hu, Pei-Wei Zhang, Jian-Guo Chen, Shuang-Qi Gao, Zu-Cheng Shen
Publikováno v:
Addiction Biology. 25
Cocaine is a common abused drug that can induce abnormal synaptic and immune responses in the central nervous system (CNS). High mobility group box 1 (HMGB1) is one kind of inflammatory molecules that is expressed both on neurons and immune cells. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e79084ad0727a9352b06f2930fb4311
https://doi.org/10.1111/adb.12739
https://doi.org/10.1111/adb.12739
Autor:
Fang Wang, Jun-Feng Xu, Hai-Yun Zhou, Qian-Qian Cui, Jian-Guo Chen, Peng-Fei Wu, Shi-Ge Xue, Jin-Gang He, Li-Hong Long, Bin Zhou, Shuang-Qi Gao, Zhuang-Li Hu
Publikováno v:
Biological psychiatry. 86(2)
Background The basolateral amygdala (BLA) has been widely implicated in the pathophysiology of major depressive disorder. A-kinase anchoring protein 150 (AKAP150) directs kinases and phosphatases to synaptic glutamate receptors, controlling synaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d61dea8f7be37b0e527049b8886d51
https://pubmed.ncbi.nlm.nih.gov/31076080
https://pubmed.ncbi.nlm.nih.gov/31076080
Autor:
Hui-Ling Zheng, Xia-Ping Yao, Wen-Hui Liu, Zhi-Xuan Xia, Jia-Jing Lu, Jian-Guo Chen, Li-Hong Long, Tai-Lei Nie, Peng-Fei Wu, Fang Wang, Zu-Cheng Shen, Shao-Qi Zhang, Qiao Deng, Shuang-Qi Gao, Zhuang-Li Hu
Publikováno v:
Biological psychiatry. 85(3)
Background Benzodiazepines (BZDs) have been used to treat anxiety disorders for more than five decades as the allosteric modulator of the gamma-aminobutyric acid A receptor (GABAAR). Little is known about other mechanisms of BZDs. Here, we describe h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956e8814f2ea5da4aca31b76df36fcab
https://pubmed.ncbi.nlm.nih.gov/30454851
https://pubmed.ncbi.nlm.nih.gov/30454851