Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shuanfang Li"'
Autor:
Retha R. Newbold, Shuanfang Li, John A. McLachlan, Barbara J. Davis, J. Carl Barrett, Roberta Hansman
Publikováno v:
Molecular Carcinogenesis. 38:78-84
Perinatal exposure to diethylstilbestrol (DES) induces reproductive tract cancers later in life in both humans and animals. Because there is no clear evidence that perinatal DES exposure induces gene mutation, we proposed that perinatal DES exposure
Publikováno v:
Gynecologic Oncology. 90:123-130
Objective Despite the high prevalence of uterine leiomyoma in women, little is known about the pathophysiology of this tumor. This study intends to define the epigenetic modulation of this tumor. Methods Twenty-three pairs of leiomyomas and their adj
Publikováno v:
Annals of the New York Academy of Sciences. 983:161-169
DNA methylation is an epigenetic mechanism that regulates chromosomal stability and gene expression. Abnormal DNA methylation patterns have been observed in many types of human tumors, including those of the breast, prostate, colon, thyroid, stomach,
Autor:
Lilia I. Melnik, Bridgette M. Collins-Burow, Carol H. Carter-Wientjes, Thomas E. Wiese, John A. McLachlan, Bich N. Duong, Matthew E. Burow, Stephen M. Boue, Thomas E. Cleveland, Shuanfang Li
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:1750-1758
The flavonoid family of phytochemicals, particularly those derived from soy, has received attention regarding their estrogenic activity as well as their effects on human health and disease. In addition to these flavonoids other phytochemicals, includ
Autor:
Valerie P. Wilson, Gloria R. Davis, John A. McLachlan, Shuanfang Li, Rachele M. Williams, Tung-Chin Chiang
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:454-457
Wnt-7a gene not only guides the development of the anterior-posterior axis in the female reproductive tract, but also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. This gene is also responsive to
Autor:
John A. McLachlan, Masahiko Negishi, Matthew E. Burow, J. Carl Barrett, Liang Ma, Retha R. Newbold, Tung-Chin Chiang, Shuanfang Li
Publikováno v:
Molecular Carcinogenesis. 32:213-219
Mouse abdominal B–like Hoxa genes are expressed and functionally required in the developing reproductive tracts. Mice lacking either Hoxa-10 or Hoxa-11, two of the AbdB Hoxa genes, exhibit abnormal uterine development similar to that induced by in
Autor:
Shuanfang Li
Publikováno v:
Histochemistry. 102:405-413
The proliferative activities of the different cellular compartments of the developing mouse ovary, uterus, and oviduct were studied by radioautographic assessment of DNA synthesis with [3H]-thymidine labeling and by immunohistochemical staining of pr
Publikováno v:
Annals of the New York Academy of Sciences. 983
DNA methylation is an epigenetic mechanism that regulates chromosomal stability and gene expression. Abnormal DNA methylation patterns have been observed in many types of human tumors, including those of the breast, prostate, colon, thyroid, stomach,
Publikováno v:
Gynecologic oncology. 92(2)
Objectives . Cyclooxygenase-1 and 2 (COX-1 and COX-2) play important roles in normal physiology and are often dysregulated in neoplastic tissues. The present study determines whether COX-1 and COX-2 are expressed in ovarian cancers and whether the pa
Autor:
Shuanfang Li, John A. McLachlan
Publikováno v:
Annals of the New York Academy of Sciences. 948
Uterine leiomyomas or fibroids are classified as a benign uterine disease in that the polyps display no malignant growth. However, uterine leiomyomas are a leading cause of morbidity, infertility, and hysterectomy in women. Since leiomyomas are known