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pro vyhledávání: '"Shuan-Yu Hou"'
Autor:
Shuan Yu Hou, Karl Degenhardt, Sophie Astrof, Sonam Dhiman, Ashok Mittal, Xia Wang, Dong Liang
Publikováno v:
Developmental Biology. 395:232-244
Integrin α5-null embryos die in mid-gestation from severe defects in cardiovascular morphogenesis, which stem from defective development of the neural crest, heart and vasculature. To investigate the role of integrin α5β1 in cardiovascular develop
Publikováno v:
Developmental Biology. 381(1):73-82
Fibronectin and its major receptor, integrin α5β1 are required for embryogenesis. These mutants have similar phenotypes, although, defects in integrin α5-deficient mice are milder. In this paper, we examined heart development in those mutants, in
Autor:
Shuan-Yu Hou, Richard O. Hynes, Scott A. Holley, Ashok Mittal, Dörthe Jülich, Charles A. Whittaker, Maria V. Pulina, Sophie Astrof
Publikováno v:
Developmental Biology. 354(2):208-220
Studies in Xenopus laevis suggested that cell-extracellular matrix (ECM) interactions regulate the development of the left–right axis of asymmetry; however, the identities of ECM components and their receptors important for this process have remain
Fibronectin and integrin alpha 5 play essential roles in the development of the cardiac neural crest
Publikováno v:
Mechanisms of Development. 127:472-484
Cardiac neural crest (CNC) plays a requisite role during cardiovascular development and defects in the formation of CNC-derived structures underlie several common forms of human congenital birth defects. Migration of the CNC cells to their destinatio