Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Shuan Shian Huang"'
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 9, Pp 709-729 (2021)
Abstract The TGF‐β type V receptor (TβR‐V) mediates growth inhibition by IGFBP‐3 and TGF‐β in epithelial cells and loss of TβR‐V expression in these cells leads to development of carcinoma. The mechanisms by which TβR‐V mediates grow
Externí odkaz:
https://doaj.org/article/dffa09f980ad4e17a3c2da8ed5414a8d
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 9, Pp 709-729 (2021)
FASEB BioAdvances
FASEB BioAdvances
The TGF‐β type V receptor (TβR‐V) mediates growth inhibition by IGFBP‐3 and TGF‐β in epithelial cells and loss of TβR‐V expression in these cells leads to development of carcinoma. The mechanisms by which TβR‐V mediates growth inhibi
Autor:
Frank E. Johnson, Chun-Lin Chen, Jung San Huang, Jia‐Ming Chang, I-Hua Liu, Shuan Shian Huang
Publikováno v:
Journal of Cellular Biochemistry. 118:1387-1400
For several decades, cholesterol has been thought to cause ASCVD. Limiting dietary cholesterol intake has been recommended to reduce the risk of the disease. However, several recent epidemiological studies do not support a relationship between dietar
Publikováno v:
Journal of Cellular Biochemistry. 117:1568-1579
Dimethyl sulfoxide (DMSO) is used to treat many diseases/symptoms. The molecular basis of the pharmacological actions of DMSO has been unclear. We hypothesized that DMSO exerts some of these actions by enhancing TGF-β activity. Here we show that DMS
Publikováno v:
Journal of Cellular Biochemistry. 117:860-871
Regular consumption of moderate amounts of ethanol has important health benefits on atherosclerotic cardiovascular disease (ASCVD). Overindulgence can cause many diseases, particularly alcoholic liver disease (ALD). The mechanisms by which ethanol ca
Publikováno v:
Journal of cellular physiology. 233(4)
CRSBP-1 (mammalian LYVE-1) is a membrane glycoprotein highly expressed in lymphatic endothelial cells (LECs). It has multiple ligands, including hyaluronic acid (HA) and growth factors/cytokines (e.g., PDGF-BB and VEGF-A) containing CRS motifs (clust
Autor:
Wen-Han Chen, Shuan Shian Huang, Andrew Schreiner, Chiou-Hwa Yuh, Hsiao-Rong Chen, Jen-Leih Wu, Jung San Huang, Mark M. Voigt, Gen-Hwa Lin, Wen-Fang Tseng
Publikováno v:
CellBio. :228-247
LYVE-1 (also termed CRSBP-1), a 120-kDa disulfide-linked dimeric type I membrane glycoprotein, is a specific marker for lymphatic endothelial cells (LECs) and exhibits multiple ligand (hyaluronic acid and growth factors/cytokines) binding activity in
Publikováno v:
FEBS Letters. 586:1480-1487
CRSBP-l/LYVE-1 ligands (PDGF-BB, VEGF-A165 and hyaluronic acid) have been shown to induce opening of lymphatic intercellular junctions in vitro and in vivo by stimulating contraction of lymphatic endothelial cells (LECs). The mechanism by which CRSBP
Publikováno v:
Journal of Cell Science. 122:1863-1871
Clathrin-dependent endocytosis is believed to be involved in TGFbeta-stimulated cellular responses, but the subcellular locus at which TGFbeta induces signaling remains unclear. Here, we demonstrate that inhibitors of clathrin-dependent endocytosis,
Publikováno v:
Journal of Cellular Physiology. 215:223-233
Transforming growth factor-beta (TGF-beta) responsiveness in cultured cells can be modulated by TGF-beta partitioning between lipid raft/caveolae- and clathrin-mediated endocytosis pathways. The TbetaR-II/TbetaR-I binding ratio of TGF-beta on the cel