Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shuaishuai Teng"'
Autor:
Shasha Li, Ming Yang, Shuaishuai Teng, Kequan Lin, Yumei Wang, Yanmei Zhang, Wei Guo, Dong Wang
Publikováno v:
Pharmacological Research, Vol 195, Iss , Pp 106896- (2023)
Tumor metastasis causes over 90% of cancer related death and no currently available therapies target it. However, there is limited understanding regarding the epigenetic regulation of genes during this complex process. Here by integrating single-cell
Externí odkaz:
https://doaj.org/article/a2b977f562284764905bbfd741e05c53
Autor:
Liuqing Yang, Kequan Lin, Lin Zhu, Huili Wang, Shuaishuai Teng, Lijun Huang, Shiyi Zhou, Guanbin Zhang, Zhi John Lu, Dong Wang
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
A loss-of-function screen reveals a role for lncRNA DARS-AS1 in promoting cancer cell proliferation and further experiments shows DARS-AS1 regulates the PACT-PKR pathway, overall suggesting it as a potential target for cancer therapy and prognosis.
Externí odkaz:
https://doaj.org/article/908ff5ed50a8437bb3e996e14345ab25
Autor:
Wei Guo, Yanmei Zhang, Ivan Garcia-Bassets, Zai Chang, Kequan Lin, Shuaishuai Teng, Pengyuan Wang, Zhi John Lu, Rui Qi, Ming Yang, Qunsheng Ji, Yiming Huang, Shasha Li, Yujing Cheng, Yang Eric Li, Dong Wang, Yang Cao, Qingyang Gu, Qianyu Wang, Shanwen Chen
Publikováno v:
Cell Res
Metastasis, the development of secondary malignant growths at a distance from a primary tumor, is the cause of death for 90% of cancer patients, but little is known about how metastatic cancer cells adapt to and colonize new tissue environments. Here
Autor:
Liuqing Yang, Kequan Lin, Lin Zhu, Huili Wang, Shuaishuai Teng, Lijun Huang, Shiyi Zhou, Guanbin Zhang, Zhi John Lu, Dong Wang
Publikováno v:
Communications biology. 5(1)
Cancer cells evolve various mechanisms to overcome cellular stresses and maintain progression. Protein kinase R (PKR) and its protein activator (PACT) are the initial responders in monitoring diverse stress signals and lead to inhibition of cell prol
Autor:
Shuaishuai Teng, Guo Yong, Suwei Zhang, Jianqing Zhao, Shasha Li, Guannan Su, Zhi John Lu, Dong Wang, Haiyan Wang, Wenyan Qin, Junquan Xu, Yu Zhang, Qianyong Zhu
Publikováno v:
Briefings in Bioinformatics. 20:1420-1433
Circular RNAs (circRNAs) are emerging as a new class of endogenous and regulatory noncoding RNAs in latest years. With the widespread application of RNA sequencing (RNA-seq) technology and bioinformatics prediction, large numbers of circRNAs have bee
Autor:
Shuaishuai Teng, Xilinqiqige Bao, Zhi John Lu, Yifei Dai, Huili Wang, Kequan Lin, Lu Li, Dong Wang
Publikováno v:
Briefings in bioinformatics. 21(6)
The methodologies for evaluating similarities between gene expression profiles of different perturbagens are the key to understanding mechanisms of actions (MoAs) of unknown compounds and finding new indications for existing drugs. L1000-based next-g
Autor:
Zhi John Lu, Yang Li, Shuaishuai Teng, Kequan Lin, Qianyu Wang, Yiming Huang, Yujing Cheng, Shasha Li, Rui Qi, Ming Yang, Dong Wang
SUMMARYTumor metastasis is the cause of death for 90% of cancer patients, and no currently-available therapies target this multi-step process in which cancer cells spread from the local tissue of a primary tumor to distant organs where they establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9293518ba871f066ac992b5932f2d027
Publikováno v:
Cancer Research. 79:4334-4334
Metastasis is the cause of death for 90% of cancer patients, but little is known about how cancer cells adapt to and colonize new tissue environments. Colorectal cancer (CRC) is the third most common cancer and the fourth most common cancer cause of