Zobrazeno 1 - 10
of 10
pro vyhledávání: '"ShuaiXin He"'
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114420- (2024)
Summary: A DNA double-strand break (DSB) jeopardizes genome integrity and endangers cell viability. Actively transcribed genes are particularly detrimental if broken and need to be repressed. However, it remains elusive how fast the repression is ini
Externí odkaz:
https://doaj.org/article/b023fc2e986e45538ccde4ad4305d972
Publikováno v:
eLife, Vol 9 (2020)
RNA granules are protein/RNA condensates. How specific mRNAs are recruited to cytoplasmic RNA granules is not known. Here, we characterize the transcriptome and assembly of P granules, RNA granules in the C. elegans germ plasm. We find that P granule
Externí odkaz:
https://doaj.org/article/9e4b10e3533e4857b1b554528c08c9fe
Autor:
Taekjip Ha, Yuta Nihongaki, Shiva Razavi, Shuaixin He, Yang Liu, Roger S. Zou, Bin Wu, Xiaoguang Li
Publikováno v:
Science
Very fast CRISPR on demand Numerous efforts have been made to improve the temporal resolution of CRISPR-Cas9–mediated DNA cleavage to the hour time scale. Liu et al. developed a Cas9 system that achieved genome-editing manipulation at the second ti
Publikováno v:
Proc Natl Acad Sci U S A
Accumulating evidence suggests participation of RNA-binding proteins with intrinsically disordered domains (IDPs) in the DNA damage response (DDR). These IDPs form liquid compartments at DNA damage sites in a poly(ADP ribose) (PAR)-dependent manner.
Publikováno v:
Biophysical Journal. 122:157a
Animals with germ plasm assemble cytoplasmic RNA granules (germ granules) that segregate with the embryonic germ lineage. How germ granules assemble and recruit RNA is not well understood. Here we characterize the assembly and RNA composition of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0145df57aa24d4022cbdce2094d5bc7
Publikováno v:
Biophysical Journal. 118:29a
Autor:
Lee, Chih-Yung S., Putnam, Andrea, Tu Lu, ShuaiXin He, Ouyang, John Paul T., Seydoux, Geraldine
Publikováno v:
eLife; 2020, p1-31, 31p, 5 Graphs
Autor:
Pu Zheng, Huan Wang, Jing Liang, Shuaixin He, Zhou Yu, Xingjie Pan, Shiyu Liu, Hailing Shi, Yuhang Hou, Can Cui, Qi Ouyang, Yihao Zhang, Haoqian Zhang, Haoran Xue, Helena Viets, Shuobing Chen
Publikováno v:
ACS synthetic biology. 3(12)
Aromatic pollutants in the environments pose significant threat to human health due to their persistence and toxicity. Here, we report the design and comprehensive characterization of a set of aromatic biosensors constructed using green fluorescence