Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Shu-wen Teng"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 3, Pp 437-448 (2024)
Abstract Overall survival is vital for approving new anticancer drugs but is often impractical for early‐phase studies. The tumor growth inhibition‐overall survival (TGI‐OS) model could bridge the gap between early‐ and late‐stage developme
Externí odkaz:
https://doaj.org/article/51ddff0d21aa4af6bf831a0e6275edce
Autor:
Shu‐Wen Teng, Yu‐Cheng Su, Ravikumar Pallantla, Madhav Channavazzala, Rukmini Kumar, Yucheng Sheng, Hao Wang, Crystal Wang, Archie Tse
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 9, Pp 1347-1357 (2023)
Abstract As a result of the escalating number of new cancer treatments being developed and competition among pharmaceutical companies, decisions regarding how to proceed with phase III trials are frequently based on findings from either single‐arm
Externí odkaz:
https://doaj.org/article/eaf3290c6626496a991edaccb119063c
Autor:
Shu‐Wen Teng, Jessica N Schaffer, Kimberly C Tu, Pankaj Mehta, Wenyun Lu, N P Ong, Bonnie L Bassler, Ned S Wingreen
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-14 (2011)
Abstract Quorum sensing is a chemical signaling mechanism used by bacteria to communicate and orchestrate group behaviors. Multiple feedback loops exist in the quorum‐sensing circuit of the model bacterium Vibrio harveyi. Using fluorescence microsc
Externí odkaz:
https://doaj.org/article/5cbd1e28512543dd92ab26912999d981
Autor:
Daniel Snell, Tea Gunde, Stefan Warmuth, Peter Lichtlen, Linlin Liu, Shu-wen Teng, Lan Zhang, ChaoHsuan Pan, Peiqi Li, Julia Tietz, Matthias Brock, Alexandre Simonim, Christian Hess, Christopher Weinert, Maria Johansson, Bithi Chatterjeee, Nicole Bassler, Niels Kirk, Catia Mendes, Robin Heiz, Naomi Flueckiger, Dania Diem, Dana Mahler, Belinda Wickihalder, Simone Muntwiler, Sandro Wagen, Elmar vom Baur, Archie N. Tse, David Urech
Publikováno v:
Cancer Research. 82:2870-2870
Antagonistic molecules targeting the PD-1/PD-L1 axis have shown excellent activity in the clinic. However, the majority of patients do not respond to the therapy due to multifaceted reasons implicating a non-effective activation of the immune system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c66e2a2e3962a5347dc40d5b43afcb4
https://doi.org/10.1158/1538-7445.am2022-2870
https://doi.org/10.1158/1538-7445.am2022-2870
Autor:
Shu-Wen Teng, Michael Hafey, Jeanine Ballard, Xinjie Lin, Changhong Yun, Vijay More, Robert Houle, Ravi Katwaru, Ann Thomas, Grace Chan, Kim Michel, Yutai Li, Kara Pearson, Christopher Gibson
Publikováno v:
Computational Toxicology. 22:100224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fef461581c647e4a98daa11bb759213
https://doi.org/10.1016/j.comtox.2022.100224
https://doi.org/10.1016/j.comtox.2022.100224
Autor:
Shu-Wen Teng1, Mukherji, Shankar1, Moffitt, Jeffrey R.2, de Buyl, Sophie3, O'Shea, Erin K.1 erin_oshea@harvard.edu
Publikováno v:
Science. 5/10/2013, Vol. 340 Issue 6133, p737-740. 4p.
Autor:
Yen Sun, Hsiao-Ching Chen, Chen-Yuan Dong, Shu-Wen Teng, Tze-Yu Lin, Ching-Chuan Jiang, Hsuan-Shu Lee, Ling-Ling Chiou, Wen Lo
Publikováno v:
Tissue Engineering. 12:2835-2841
The noninvasive imaging of tissue engineering constructs is vital for understanding the physiological changes in construct formation and the design of improved products for therapeutic purposes. In this work, we use the combination of multiphoton aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8dbcbd30975eef08edb9daa4b83216
https://doi.org/10.1089/ten.2006.12.2835
https://doi.org/10.1089/ten.2006.12.2835
The remarkably stable circadian oscillations of single cyanobacteria enable a population of growing cells to maintain synchrony for weeks. The cyanobacterial pacemaker is a posttranslational regulation (PTR) circuit that generates circadian oscillati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9bfcd177011a68f5e4db393d655e7d
https://doi.org/10.1126/science.1230996
https://doi.org/10.1126/science.1230996
Autor:
Nai Phuan Ong, Shu Wen Teng, Jessica N. Schaffer, Ned S. Wingreen, Kimberly C. Tu, Pankaj Mehta, Wenyun Lu, Bonnie L. Bassler
Publikováno v:
Molecular Systems Biology
Single-cell quantification of the input–output relation of the quorum-sensing circuit reveals how Vibrio harveyi employs multiple feedback loops to simultaneously control quorum-sensing signal integration and to ensure signal transmission fidelity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb9d153ddd5c4095c37d0970db6991c
https://doi.org/10.1038/msb.2011.30
https://doi.org/10.1038/msb.2011.30
Autor:
Shu-Wen Teng, Ned S. Wingreen, Tao Long, Nai Phuan Ong, Pankaj Mehta, Kimberly C. Tu, Bonnie L. Bassler, Yufang Wang
Publikováno v:
Biophysical journal. 98(9)
Quorum sensing is the mechanism by which bacteria communicate and synchronize group behaviors. Quantitative information on parameters such as the copy number of particular quorum-sensing proteins should contribute strongly to understanding how the qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b64e0e3e872b2d8b36ab3dd4825391
https://pubmed.ncbi.nlm.nih.gov/20441767
https://pubmed.ncbi.nlm.nih.gov/20441767