Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Shu-qing Chen"'
Autor:
Ying Shen, Shi-jie Jin, Yi-chang Chen, Wen-hui Liu, Yi-ming Li, Wen-yi Zhao, Ying-chun Xu, Shu-qing Chen, Wen-bin Zhao
Publikováno v:
Pharmacological Research, Vol 192, Iss , Pp 106781- (2023)
Targeting single tumor antigens makes it difficult to provide sufficient tumor selectivity for T cell engagers (TCEs), leading to undesirable toxicity and even treatment failure, which is particularly serious in solid tumors. Here, we designed novel
Externí odkaz:
https://doaj.org/article/43e626db6e714bb1b35b199600e54ea0
Autor:
Kun Hu, Qian Xiang, Zhe Wang, Guang-yan Mu, Zhuo Zhang, Ling-yue Ma, Qiu-fen Xie, Shu-qing Chen, Shuang Zhou, Xiao-dan Zhang, Yi-min Cui
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Human leukocyte antigen (HLA) alleles are implicated in drug-induced hypersensitivity, including by nevirapine and abacavir. The purpose of this meta-analysis was to evaluate the relationship between HLA polymorphisms and hypersen
Externí odkaz:
https://doaj.org/article/a98618ef6b16496089f6305bd1599d6a
Autor:
Yi-Sheng Sun, Jing-Jing Zhou, Han-Ping Zhu, Fang Xu, Wen-Bin Zhao, Hang-Jing Lu, Zhen Wang, Shu-Qing Chen, Ping-Ping Yao, Jian-Min Jiang, Zhan Zhou
Publikováno v:
Viruses, Vol 13, Iss 10, p 1936 (2021)
The novel coronavirus pneumonia (COVID-19) pandemic is a great threat to human society and now is still spreading. Although several vaccines have been authorized for emergency use, only one recombinant subunit vaccine has been permitted for widesprea
Externí odkaz:
https://doaj.org/article/1d12d686d4d24136808169d495f634d4
Autor:
Wen-Bin Zhao, Ying Shen, Wen-Hui Liu, Yi-Ming Li, Shi-Jie Jin, Ying-Chun Xu, Li-Qiang Pan, Zhan Zhou, Shu-Qing Chen
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 790 (2021)
The specific recognition of T cell receptors (TCR) and peptides presented by human leukocyte antigens (pHLAs) is the core step for T cell triggering to execute anti-tumor activity. However, TCR assembly and soluble expression are challenging, which p
Externí odkaz:
https://doaj.org/article/87999bd6ea2640d1bdaf558aa388380c
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 14, Iss 5, Pp 298-313 (2016)
The interindividual genetic variations in drug metabolizing enzymes and transporters influence the efficacy and toxicity of numerous drugs. As a fundamental element in precision medicine, pharmacogenomics, the study of responses of individuals to med
Externí odkaz:
https://doaj.org/article/19fa756467a2427c9ba3208fcfa8d331
Autor:
Wei An, Hong-Wei Kuang, Yong-Qing Liu, Nan Peng, Ke-Min Xu, Huan Xu, Peng Zhang, Ke-Bai Wang, Shu-Qing Chen, Yan-Xia Zhang
Publikováno v:
Journal of Palaeogeography, Vol 5, Iss 1, Pp 72-99 (2016)
The mass burial of dinosaur bone fossils in the Late Cretaceous Wangshi Group in Zhucheng, Shandong Province has been a research focus in recent years. However, the provenance of the dinosaur bone fossils and the accurate depositional age of the bone
Externí odkaz:
https://doaj.org/article/1cbd13391dbf49a39cc96e4c12f16828
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 16, p 3912 (2019)
Wilms tumor 1 (WT1) oncoprotein is an intracellular oncogenic transcription factor which is barely expressed in normal adult tissues but over expressed in a variety of leukemias and solid cancers. WT1-derived HLA-A*02:01 T cell epitope, RMFPNAPYL (RM
Externí odkaz:
https://doaj.org/article/2dfb715e13214e1dbd56228e5487e3e0
Autor:
Shu-Qing Chen, Ze-Shi Wang, Yi-Xiao Ma, Wei Zhang, Jian-Liang Lu, Yue-Rong Liang, Xin-Qiang Zheng
Publikováno v:
Molecules, Vol 23, Iss 3, p 512 (2018)
As the population ages, neurodegenerative diseases such as Parkinson’s disease (PD) and Alzheimer’s disease (AD) impose a heavy burden on society and families. The pathogeneses of PD and AD are complex. There are no radical cures for the diseases
Externí odkaz:
https://doaj.org/article/ee573305359a4125b88579aea8787273
Autor:
Hua-Lei Lei, Jia-Dong Wu, Mao-Lin Huang, Jia-Hao Hong, Shuai Lin, Zhi-Hao Chen, Shu-Qing Chen, Yu Chen
Publikováno v:
Optik. 268:169779
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1322bdb2c81074f6952070a97684dd6
https://doi.org/10.1016/j.ijleo.2022.169779
https://doi.org/10.1016/j.ijleo.2022.169779
Publikováno v:
Materials Science Forum. 941:292-298
The present investigation was made to study the effect of Al on the microstructure and mechanical properties of hot-rolled medium-Mn TRIP steel (abbreviated as Al-TRIP). As a contrast, a Si-added medium-Mn TRIP steel (abbreviated as Si-TRIP) was also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2671f678053787a62b6b043b1430649b
https://doi.org/10.4028/www.scientific.net/msf.941.292
https://doi.org/10.4028/www.scientific.net/msf.941.292